Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C14H12ClN3O4S2 |
| Molecular Weight | 385.846 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NS(=O)(=O)C1=CC=C(C=C1)S(=O)(=O)NC2=C3NC=C(Cl)C3=CC=C2
InChI
InChIKey=SETFNECMODOHTO-UHFFFAOYSA-N
InChI=1S/C14H12ClN3O4S2/c15-12-8-17-14-11(12)2-1-3-13(14)18-24(21,22)10-6-4-9(5-7-10)23(16,19)20/h1-8,17-18H,(H2,16,19,20)
| Molecular Formula | C14H12ClN3O4S2 |
| Molecular Weight | 385.846 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:40:43 UTC 2023
by
admin
on
Fri Dec 15 15:40:43 UTC 2023
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| Record UNII |
WJ98J3NM90
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| Record Status |
Validated (UNII)
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| Record Version |
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-
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| Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C29577
Created by
admin on Fri Dec 15 15:40:43 UTC 2023 , Edited by admin on Fri Dec 15 15:40:43 UTC 2023
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NCI_THESAURUS |
C2185
Created by
admin on Fri Dec 15 15:40:43 UTC 2023 , Edited by admin on Fri Dec 15 15:40:43 UTC 2023
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| Code System | Code | Type | Description | ||
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C25797
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145431
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SUB121367
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WJ98J3NM90
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100000144620
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CHEMBL77517
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E7070
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8199
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216468
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m6256
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admin on Fri Dec 15 15:40:43 UTC 2023 , Edited by admin on Fri Dec 15 15:40:43 UTC 2023
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PRIMARY | Merck Index | ||
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165668-41-7
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DB06370
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RR-50
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DTXSID50168008
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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TARGET->DEGRADER |
Indisulam induces a ternary protein complex between RNA Binding Motif 39 (RBM39) and the E3 ubiquitin ligase receptor DDB1 and CUL4 associated factor 15 (DCAF15) resulting in rapid proteasomal degradation of RBM39, aberrant RNA splicing and cell death.
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TARGET->DEGRADER |
Indisulam induces a ternary protein complex between RNA Binding Motif 39 (RBM39) and the E3 ubiquitin ligase receptor DDB1 and CUL4 associated factor 15 (DCAF15) resulting in rapid proteasomal degradation of RBM39, aberrant RNA splicing and cell death.
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TARGET -> INHIBITOR |
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
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