BENZNIDAZOLE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H12N4O3
Molecular Weight	260.2487
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of BENZNIDAZOLE

Structure Search

SMILES

[O-][N+](=O)C1=NC=CN1CC(=O)NCC2=CC=CC=C2

InChI

InChIKey=CULUWZNBISUWAS-UHFFFAOYSA-N

InChI=1S/C12H12N4O3/c17-11(14-8-10-4-2-1-3-5-10)9-15-7-6-13-12(15)16(18)19/h1-7H,8-9H2,(H,14,17)

HIDE SMILES / InChI

Molecular Formula	C12H12N4O3
Molecular Weight	260.2487
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:45:00 UTC 2023` Edited by `admin` on `Sat Dec 16 17:45:00 UTC 2023`
Record UNII	YC42NRJ1ZD
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

BENZNIDAZOLE

Official Name

English

benznidazole [INN]

Common Name

English

BENZONIDAZOL

Common Name

English

ROCHAGAN

Brand Name

English

RO-7-1051

Code

English

NSC-299972

Code

English

BENZNIDAZOLE [WHO-IP]

Common Name

English

BENZNIDAZOLE [USAN]

Common Name

English

BENZNIDAZOLE [MART.]

Common Name

English

Imidazole-1-acetamide, N-benzyl-2-nitro-

Systematic Name

English

RO 07-1051

Code

English

1H-IMIDAZOLE-1-ACETAMIDE, 2-NITRO-N-(PHENYLMETHYL)-

Systematic Name

English

BENZNIDAZOLE [ORANGE BOOK]

Common Name

English

BENZNIDAZOLUM [WHO-IP LATIN]

Common Name

English

BENZNIDAZOLE [MI]

Common Name

English

RO-07-1051

Code

English

Benznidazole [WHO-DD]

Common Name

English

N-BENZYL-2-NITROIMIDAZOLE-1-ACETAMIDE

Systematic Name

English

RADANIL

Brand Name

English

Classification Tree Code System Code

WHO-ESSENTIAL MEDICINES LIST

6.5.5.2

Created by admin on Sat Dec 16 17:45:01 UTC 2023 , Edited by admin on Sat Dec 16 17:45:01 UTC 2023

NCI_THESAURUS

C277

Created by admin on Sat Dec 16 17:45:01 UTC 2023 , Edited by admin on Sat Dec 16 17:45:01 UTC 2023

FDA ORPHAN DRUG

425214

Created by admin on Sat Dec 16 17:45:01 UTC 2023 , Edited by admin on Sat Dec 16 17:45:01 UTC 2023

FDA ORPHAN DRUG

586517

Created by admin on Sat Dec 16 17:45:01 UTC 2023 , Edited by admin on Sat Dec 16 17:45:01 UTC 2023

FDA ORPHAN DRUG

719219

Created by admin on Sat Dec 16 17:45:01 UTC 2023 , Edited by admin on Sat Dec 16 17:45:01 UTC 2023

WHO-ATC

P01CA02

Created by admin on Sat Dec 16 17:45:01 UTC 2023 , Edited by admin on Sat Dec 16 17:45:01 UTC 2023

Code System Code Type Description

DRUG BANK

DB11989

Created by admin on Sat Dec 16 17:45:01 UTC 2023 , Edited by admin on Sat Dec 16 17:45:01 UTC 2023

PRIMARY

EVMPD

SUB05753MIG

Created by admin on Sat Dec 16 17:45:01 UTC 2023 , Edited by admin on Sat Dec 16 17:45:01 UTC 2023

PRIMARY

PUBCHEM

31593

Created by admin on Sat Dec 16 17:45:01 UTC 2023 , Edited by admin on Sat Dec 16 17:45:01 UTC 2023

PRIMARY

NCI_THESAURUS

C1013

Created by admin on Sat Dec 16 17:45:01 UTC 2023 , Edited by admin on Sat Dec 16 17:45:01 UTC 2023

PRIMARY

ChEMBL

CHEMBL110

Created by admin on Sat Dec 16 17:45:01 UTC 2023 , Edited by admin on Sat Dec 16 17:45:01 UTC 2023

PRIMARY

NSC

299972

Created by admin on Sat Dec 16 17:45:01 UTC 2023 , Edited by admin on Sat Dec 16 17:45:01 UTC 2023

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WHO INTERNATIONAL PHARMACOPEIA

BENZNIDAZOLE

Created by admin on Sat Dec 16 17:45:01 UTC 2023 , Edited by admin on Sat Dec 16 17:45:01 UTC 2023

PRIMARY

Description: A yellowish powder; odourless or almost odourless. Solubility: Practically insoluble in water; sparingly soluble in acetone R; slightly soluble in methanol R; very slightly soluble in ethanol (~750 g/l) TS. Category: Antiprotozoal drug. Storage: Benznidazole should be kept in a well-closed container, protected from light. Requirement: Benznidazole contains not less than 98.5% and not more than the equivalent of 101.5% of C12H12N4O3, calculated with reference to the dried substance.

DRUG CENTRAL

322

Created by admin on Sat Dec 16 17:45:01 UTC 2023 , Edited by admin on Sat Dec 16 17:45:01 UTC 2023

PRIMARY

RXCUI

18994

Created by admin on Sat Dec 16 17:45:01 UTC 2023 , Edited by admin on Sat Dec 16 17:45:01 UTC 2023

PRIMARY

RxNorm

EPA CompTox

DTXSID9046570

Created by admin on Sat Dec 16 17:45:01 UTC 2023 , Edited by admin on Sat Dec 16 17:45:01 UTC 2023

PRIMARY

LACTMED

Benznidazole

Created by admin on Sat Dec 16 17:45:01 UTC 2023 , Edited by admin on Sat Dec 16 17:45:01 UTC 2023

PRIMARY

INN

3541

Created by admin on Sat Dec 16 17:45:01 UTC 2023 , Edited by admin on Sat Dec 16 17:45:01 UTC 2023

PRIMARY

FDA UNII

YC42NRJ1ZD

Created by admin on Sat Dec 16 17:45:01 UTC 2023 , Edited by admin on Sat Dec 16 17:45:01 UTC 2023

PRIMARY

CHEBI

133833

Created by admin on Sat Dec 16 17:45:01 UTC 2023 , Edited by admin on Sat Dec 16 17:45:01 UTC 2023

PRIMARY

WIKIPEDIA

BENZNIDAZOLE

Created by admin on Sat Dec 16 17:45:01 UTC 2023 , Edited by admin on Sat Dec 16 17:45:01 UTC 2023

PRIMARY

CAS

22994-85-0

Created by admin on Sat Dec 16 17:45:01 UTC 2023 , Edited by admin on Sat Dec 16 17:45:01 UTC 2023

PRIMARY

DAILYMED

YC42NRJ1ZD

Created by admin on Sat Dec 16 17:45:01 UTC 2023 , Edited by admin on Sat Dec 16 17:45:01 UTC 2023

PRIMARY

USAN

EF-13

Created by admin on Sat Dec 16 17:45:01 UTC 2023 , Edited by admin on Sat Dec 16 17:45:01 UTC 2023

PRIMARY

MERCK INDEX

m2356

Created by admin on Sat Dec 16 17:45:01 UTC 2023 , Edited by admin on Sat Dec 16 17:45:01 UTC 2023

PRIMARY

Merck Index

SMS_ID

100000086386

Created by admin on Sat Dec 16 17:45:01 UTC 2023 , Edited by admin on Sat Dec 16 17:45:01 UTC 2023

PRIMARY

MESH

C009999

Created by admin on Sat Dec 16 17:45:01 UTC 2023 , Edited by admin on Sat Dec 16 17:45:01 UTC 2023

PRIMARY

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BINDER->LIGAND

Interaction Type:

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Amount:


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TRYPANOSOMA CRUZI

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EXCRETED UNCHANGED


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TRANSPORTER -> SUBSTRATE

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ACTIVE MOIETY

Comments:

http://apps.who.int/phint/pdf/b/Jb.6.1.47.pdf

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
CSF/PLASMA RATIO	PHARMACOKINETIC

Tmax	PHARMACOKINETIC
Biological Half-life	PHARMACOKINETIC				ELIMINATION PHARMACOKINETIC