TEMOZOLOMIDE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H6N6O2
Molecular Weight	194.1508
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TEMOZOLOMIDE

Structure Search

SMILES

CN1N=NC2=C(N=CN2C1=O)C(N)=O

InChI

InChIKey=BPEGJWRSRHCHSN-UHFFFAOYSA-N

InChI=1S/C6H6N6O2/c1-11-6(14)12-2-8-3(4(7)13)5(12)9-10-11/h2H,1H3,(H2,7,13)

HIDE SMILES / InChI

Molecular Formula	C6H6N6O2
Molecular Weight	194.1508
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:40:26 UTC 2023` Edited by `admin` on `Fri Dec 15 15:40:26 UTC 2023`
Record UNII	YF1K15M17Y
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TEMOZOLOMIDE

Official Name

English

temozolomide [INN]

Common Name

English

MK-7365

Common Name

English

NSC-362856

Code

English

TEMOZOLOMIDE [EMA EPAR]

Common Name

English

CCRG-81045

Code

English

M&B-39831

Code

English

M-39831

Code

English

TEMOZOLOMIDE [EP MONOGRAPH]

Common Name

English

METHAZOLASTONE

Common Name

English

SCH 52365

Code

English

TEMOZOLOMIDE [JAN]

Common Name

English

TEMOZOLOMIDE [USAN]

Common Name

English

TEMOZOLOMIDE [ORANGE BOOK]

Common Name

English

SCH-52365

Code

English

3,4-Dihydro-3-methyl-4-oxoimidazo[5,1-d]-as-tetrazine-8-carboxamide

Common Name

English

TEMOZOLOMIDE [USP MONOGRAPH]

Common Name

English

IMIDAZO(5,1-D)-1,2,3,5-TETRAZINE-8-CARBOXAMIDE, 3,4-DIHYDRO-3-METHYL-4-OXO-

Systematic Name

English

TEMOZOLOMIDE [USP-RS]

Common Name

English

TEMOZOLOMIDE [MART.]

Common Name

English

TEMODAL

Brand Name

English

TEMOZOLOMIDE [MI]

Common Name

English

Temozolomide [WHO-DD]

Common Name

English

M&B 39831

Code

English

TEMODAR

Brand Name

English

TEMOZOLOMIDE [VANDF]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C902

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

NDF-RT

N0000175558

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

WHO-ATC

L01AX03

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

NDF-RT

N0000000236

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

FDA ORPHAN DRUG

116798

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

EMA ASSESSMENT REPORTS

TEMOZOLOMIDE SUN (AUTHORIZED: GLIOMA, GLIOBLASTOMA)

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

FDA ORPHAN DRUG

895222

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

EMA ASSESSMENT REPORTS

TEMOZOLOMIDE TEVA (AUTHORIZED: GLIOMA, GLIOBLASTOMA)

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

EMA ASSESSMENT REPORTS

TEMOZOLOMIDE SANDOZ (AUTHORIZED: GLIOMA, GLIOBLASTOMA)

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

EMA ASSESSMENT REPORTS

TEMOZOLOMIDE HEXAL (AUTHORIZED: GLIOMA, GLIOBLASTOMA)

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

FDA ORPHAN DRUG

193904

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

WHO-VATC

QL01AX03

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

EMA ASSESSMENT REPORTS

TEMOMEDAC (AUTHORIZED: GLIOMA, GLIOBLASTOMA)

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

FDA ORPHAN DRUG

453314

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

EU-Orphan Drug

EU/3/16/1733

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

FDA ORPHAN DRUG

497215

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

EMA ASSESSMENT REPORTS

TEMODAL (AUTHORIZED: GLIOMA, GLIOBLASTOMA)

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

FDA ORPHAN DRUG

698519

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

LIVERTOX

NBK548816

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

EMA ASSESSMENT REPORTS

TEMOZOLOMIDE ACCORD (AUTHORIZED: GLIOMA, GLIOBLASTOMA

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

FDA ORPHAN DRUG

117198

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

Code System Code Type Description

EPA CompTox

DTXSID5043714

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

PRIMARY

MESH

C047246

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

PRIMARY

RXCUI

37776

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

PRIMARY

RxNorm

CAS

85622-93-1

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

PRIMARY

USAN

LL-53

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

PRIMARY

RS_ITEM_NUM

1643543

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

PRIMARY

EVMPD

SUB10889MIG

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

PRIMARY

ChEMBL

CHEMBL810

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

PRIMARY

DRUG CENTRAL

2589

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

PRIMARY

LACTMED

Temozolamide

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

PRIMARY

FDA UNII

YF1K15M17Y

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

PRIMARY

INN

6027

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

PRIMARY

CHEBI

72564

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

PRIMARY

MERCK INDEX

m10552

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

PRIMARY

Merck Index

WIKIPEDIA

TEMOZOLOMIDE

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

PRIMARY

PUBCHEM

5394

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

PRIMARY

DRUG BANK

DB00853

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

PRIMARY

SMS_ID

100000089638

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

PRIMARY

DAILYMED

YF1K15M17Y

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

PRIMARY

NSC

362856

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

PRIMARY

IUPHAR

7301

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

PRIMARY

NCI_THESAURUS

C1244

Created by admin on Fri Dec 15 15:40:26 UTC 2023 , Edited by admin on Fri Dec 15 15:40:26 UTC 2023

PRIMARY

Related Record Type Details


					YF1K15M17Y

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (HPLC)

Qualification:

USP

Amount:

Related Record Type Details


					UWA30B5Z1J

METHYLHYDRAZINE

PRODRUG -> METABOLITE ACTIVE


					PYY6H17XIV

MTIC

METABOLITE -> PARENT

Qualification:

URINE

Amount:


					3V0Y2PDE6K

4-AMINO-5-IMIDAZOLE CARBOXAMIDE

METABOLITE -> PARENT

Related Record Type Details


					7H0G4H1HOV

3-METHYL-4-OXO-3,4-DIHYDROIMIDAZO(5,1-D)(1,2,3,5)TETRAZINE-8-CARBONITRILE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					TGZ8A8PWEX

2-AZAHYPOXANTHINE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					M35A7FW55W

TEMOZOLOMIDE ACID

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					M35A7FW55W

TEMOZOLOMIDE ACID

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					3V0Y2PDE6K

4-AMINO-5-IMIDAZOLE CARBOXAMIDE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					7H0G4H1HOV

3-METHYL-4-OXO-3,4-DIHYDROIMIDAZO(5,1-D)(1,2,3,5)TETRAZINE-8-CARBONITRILE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					3V0Y2PDE6K

4-AMINO-5-IMIDAZOLE CARBOXAMIDE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					XLJ646260P

5-DIAZOIMIDAZOLE-4-CARBOXAMIDE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					XLJ646260P

5-DIAZOIMIDAZOLE-4-CARBOXAMIDE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					TGZ8A8PWEX

2-AZAHYPOXANTHINE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:

Related Record Type Details


					YF1K15M17Y

ACTIVE MOIETY