U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Mon Mar 31 22:05:10 GMT 2025
Edited
by admin
on Mon Mar 31 22:05:10 GMT 2025
Protein Type BISPECIFIC MONOCLONAL FRAGMENTS
Protein Sub Type IMMUNOGLOBULIN
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
0AHT0IC02G
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FLOTETUZUMAB
USAN   INN  
Official Name English
MGD006
Preferred Name English
RES-234
Code English
HUMANIZED, DUAL-AFFINITY RE-TARGETING, OR (DART), MOLECULE THAT RECOGNIZES BOTH CD123 AND CD3
Common Name English
S80880
Code English
FLOTETUZUMAB [USAN]
Common Name English
Flotetuzumab [WHO-DD]
Common Name English
flotetuzumab [INN]
Common Name English
S-80880
Code English
MGD-006
Code English
Classification Tree Code System Code
NCI_THESAURUS C129822
Created by admin on Mon Mar 31 22:05:10 GMT 2025 , Edited by admin on Mon Mar 31 22:05:10 GMT 2025
FDA ORPHAN DRUG 563516
Created by admin on Mon Mar 31 22:05:10 GMT 2025 , Edited by admin on Mon Mar 31 22:05:10 GMT 2025
NCI_THESAURUS C28227
Created by admin on Mon Mar 31 22:05:10 GMT 2025 , Edited by admin on Mon Mar 31 22:05:10 GMT 2025
Code System Code Type Description
USAN
DE-42
Created by admin on Mon Mar 31 22:05:10 GMT 2025 , Edited by admin on Mon Mar 31 22:05:10 GMT 2025
PRIMARY
CAS
1664355-28-5
Created by admin on Mon Mar 31 22:05:10 GMT 2025 , Edited by admin on Mon Mar 31 22:05:10 GMT 2025
PRIMARY
NCI_THESAURUS
C117238
Created by admin on Mon Mar 31 22:05:10 GMT 2025 , Edited by admin on Mon Mar 31 22:05:10 GMT 2025
PRIMARY
SMS_ID
100000181744
Created by admin on Mon Mar 31 22:05:10 GMT 2025 , Edited by admin on Mon Mar 31 22:05:10 GMT 2025
PRIMARY
FDA UNII
0AHT0IC02G
Created by admin on Mon Mar 31 22:05:10 GMT 2025 , Edited by admin on Mon Mar 31 22:05:10 GMT 2025
PRIMARY
WIKIPEDIA
Flotetuzumab
Created by admin on Mon Mar 31 22:05:10 GMT 2025 , Edited by admin on Mon Mar 31 22:05:10 GMT 2025
PRIMARY
INN
10569
Created by admin on Mon Mar 31 22:05:10 GMT 2025 , Edited by admin on Mon Mar 31 22:05:10 GMT 2025
PRIMARY
DRUG BANK
DB15223
Created by admin on Mon Mar 31 22:05:10 GMT 2025 , Edited by admin on Mon Mar 31 22:05:10 GMT 2025
PRIMARY
From To
1_241 2_249
1_22 1_90
1_140 1_214
2_23 2_94
2_143 2_219
Related Record Type Details
CD3
CD3
TARGET -> ACTIVATOR
INTERLEUKIN-3 RECEPTOR SUBUNIT ALPHA
TARGET -> INHIBITOR
Related Record Type Details
FLOTETUZUMAB
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
AMINO ACID SUBSTITUTION [1_1] Q PIDOLIC ACID SZB83O1W42
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
NCATS
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