ISOCITRATE DEHYDROGENASE (NADP) CYTOPLASMIC

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 18:36:30 GMT 2025` Edited by `admin` on `Tue Apr 01 18:36:30 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	0B98U0ML4X
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ISOCITRATE DEHYDROGENASE (NADP) CYTOPLASMIC

Common Name

English

CYTOSOLIC NADP-ISOCITRATE DEHYDROGENASE

Preferred Name

English

NADP(+)-SPECIFIC ICDH

Common Name

English

PICD

Common Name

English

IDH

Common Name

English

IDH1

Common Name

English

OXALOSUCCINATE DECARBOXYLASE

Common Name

English

Code System Code Type Description

UNIPROT

O75874

Created by admin on Tue Apr 01 18:36:30 GMT 2025 , Edited by admin on Tue Apr 01 18:36:30 GMT 2025

PRIMARY

FDA UNII

0B98U0ML4X

Created by admin on Tue Apr 01 18:36:30 GMT 2025 , Edited by admin on Tue Apr 01 18:36:30 GMT 2025

PRIMARY

EC (ENZYME CLASS)

EC 1.1.1.42

Created by admin on Tue Apr 01 18:36:30 GMT 2025 , Edited by admin on Tue Apr 01 18:36:30 GMT 2025

PRIMARY

SMS_ID

100000173992

Created by admin on Tue Apr 01 18:36:30 GMT 2025 , Edited by admin on Tue Apr 01 18:36:30 GMT 2025

PRIMARY

WIKIPEDIA

IDH1

Created by admin on Tue Apr 01 18:36:30 GMT 2025 , Edited by admin on Tue Apr 01 18:36:30 GMT 2025

PRIMARY

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Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REPLACEMENT	[1_388] [2_388]		SERINE		DEXFOSFOSERINE	VI4F0K069V
AMINO ACID REPLACEMENT	[1_41] [2_41]		TYROSINE		TYROSINE O-PHOSPHATE	2R86C98KDX
AMINO ACID REPLACEMENT	[1_125] [1_399] [2_125] [2_399]		LYSINE		N6-SUCCINYLLYSINE	3LH35AJA5L
AMINO ACID REPLACEMENT	[1_1] [2_1]		SERINE		N-ACETYLSERINE	W98518XGZ3
AMINO ACID REPLACEMENT	[1_80] [1_223] [1_232] [1_242] [1_320] [2_80] [2_223] [2_232] [2_242] [2_320]		LYSINE		N6-ACETYLLYSINE	470AD5VY1X

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER AVERAGE(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL