COAGULATION FACTOR X HUMAN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

US Approved Rx (2013)

First approved in 2013

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 20:30:38 GMT 2025` Edited by `admin` on `Mon Mar 31 20:30:38 GMT 2025`
Protein Type	ENZYME
Protein Sub Type	BLOOD COAGULATION FACTOR; SERINE PROTEASE
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	0P94UQE6SY
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

COAGULATION FACTOR X

Preferred Name

English

COAGULATION FACTOR X HUMAN

Common Name

English

FACTOR X

Common Name

English

HUMAN FACTOR X

Common Name

English

Coagadex component Coagulation Factor X (Human)

Brand Name

English

HUMAN COAGULATION FACTOR X

Common Name

English

COAGULATION FACTOR X, HUMAN

Common Name

English

Classification Tree Code System Code

WHO-ATC

B02BD13

Created by admin on Mon Mar 31 20:30:38 GMT 2025 , Edited by admin on Mon Mar 31 20:30:38 GMT 2025

FDA ORPHAN DRUG

225806

Created by admin on Mon Mar 31 20:30:38 GMT 2025 , Edited by admin on Mon Mar 31 20:30:38 GMT 2025

FDA ORPHAN DRUG

305310

Created by admin on Mon Mar 31 20:30:38 GMT 2025 , Edited by admin on Mon Mar 31 20:30:38 GMT 2025

NCI_THESAURUS

C78311

Created by admin on Mon Mar 31 20:30:38 GMT 2025 , Edited by admin on Mon Mar 31 20:30:38 GMT 2025

LOINC

49639-8

Created by admin on Mon Mar 31 20:30:38 GMT 2025 , Edited by admin on Mon Mar 31 20:30:38 GMT 2025

NDF-RT

N0000184169

Created by admin on Mon Mar 31 20:30:38 GMT 2025 , Edited by admin on Mon Mar 31 20:30:38 GMT 2025

LOINC

3222-7

Created by admin on Mon Mar 31 20:30:38 GMT 2025 , Edited by admin on Mon Mar 31 20:30:38 GMT 2025

EU-Orphan Drug

EU/3/07/471

Created by admin on Mon Mar 31 20:30:38 GMT 2025 , Edited by admin on Mon Mar 31 20:30:38 GMT 2025

LOINC

3223-5

Created by admin on Mon Mar 31 20:30:38 GMT 2025 , Edited by admin on Mon Mar 31 20:30:38 GMT 2025

FDA ORPHAN DRUG

246907

Created by admin on Mon Mar 31 20:30:38 GMT 2025 , Edited by admin on Mon Mar 31 20:30:38 GMT 2025

Code System Code Type Description

NDF-RT

N0000007914

Created by admin on Mon Mar 31 20:30:38 GMT 2025 , Edited by admin on Mon Mar 31 20:30:38 GMT 2025

PRIMARY

Blood Coagulation Factors [Chemical/Ingredient]

RXCUI

4262

Created by admin on Mon Mar 31 20:30:38 GMT 2025 , Edited by admin on Mon Mar 31 20:30:38 GMT 2025

ALTERNATIVE

RxNorm

NCI_THESAURUS

C82272

Created by admin on Mon Mar 31 20:30:38 GMT 2025 , Edited by admin on Mon Mar 31 20:30:38 GMT 2025

PRIMARY

SMS_ID

100000130073

Created by admin on Mon Mar 31 20:30:38 GMT 2025 , Edited by admin on Mon Mar 31 20:30:38 GMT 2025

PRIMARY

NDF-RT

N0000175979

Created by admin on Mon Mar 31 20:30:38 GMT 2025 , Edited by admin on Mon Mar 31 20:30:38 GMT 2025

PRIMARY

Increased Coagulation Activity [PE]

DAILYMED

0P94UQE6SY

Created by admin on Mon Mar 31 20:30:38 GMT 2025 , Edited by admin on Mon Mar 31 20:30:38 GMT 2025

PRIMARY

EVMPD

SUB13816MIG

Created by admin on Mon Mar 31 20:30:38 GMT 2025 , Edited by admin on Mon Mar 31 20:30:38 GMT 2025

PRIMARY

FDA UNII

0P94UQE6SY

Created by admin on Mon Mar 31 20:30:38 GMT 2025 , Edited by admin on Mon Mar 31 20:30:38 GMT 2025

PRIMARY

EVMPD

SUB41252

Created by admin on Mon Mar 31 20:30:38 GMT 2025 , Edited by admin on Mon Mar 31 20:30:38 GMT 2025

PRIMARY

MESH

D005170

Created by admin on Mon Mar 31 20:30:38 GMT 2025 , Edited by admin on Mon Mar 31 20:30:38 GMT 2025

PRIMARY

DRUG BANK

DB13148

Created by admin on Mon Mar 31 20:30:38 GMT 2025 , Edited by admin on Mon Mar 31 20:30:38 GMT 2025

PRIMARY

RXCUI

1426166

Created by admin on Mon Mar 31 20:30:38 GMT 2025 , Edited by admin on Mon Mar 31 20:30:38 GMT 2025

PRIMARY

LACTMED

Coagulation Factor X

Created by admin on Mon Mar 31 20:30:38 GMT 2025 , Edited by admin on Mon Mar 31 20:30:38 GMT 2025

PRIMARY

From	To
1_59	1_64
1_79	1_95
1_160	2_132
1_208	1_222
1_233	1_261
2_17	2_22
2_50	2_61
2_55	2_70
2_72	2_81
2_89	2_100
2_96	2_109
2_111	2_124

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_39
N	1_49
O	1_17
O	1_29

Related Record Type Details


					EUV85RR8DJ

Denecimig

ACTIVATOR -> TARGET

Amount:


					9NDF7JZ4M3

INHIBITOR -> TARGET

Amount:


					74RWP7W0J9

INHIBITOR -> TARGET

Amount:


					3TTT9ZD93F

Anpocogin

BINDER->LIGAND

Amount:


					3Z9Y7UWC1J

APIXABAN

INHIBITOR -> TARGET

Qualification:

Ki

Amount:


					7NL2E3F6K3

ACTIVATOR -> TARGET

Amount:


					415ZN8YW42

TIFACOGIN

INHIBITOR -> TARGET

Related Record Type Details


					0P94UQE6SY

COAGULATION FACTOR X HUMAN

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[2_6] [2_7] [2_14] [2_16] [2_19] [2_20] [2_25] [2_26] [2_29] [2_31] [2_39] [2_40]		GLUTAMIC ACID		.GAMMA.-CARBOXYGLUTAMIC ACID	16FQV4RZKL
AMINO ACID SUBSTITUTION	[2_63]		ASPARTIC ACID		.BETA.-HYDROXY-L-ASPARTIC ACID, ERYTHRO-	GDV0MSK2SG

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL