PRIMIDONE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H14N2O2
Molecular Weight	218.2518
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PRIMIDONE

Structure Search

SMILES

CCC1(C(=O)NCNC1=O)C2=CC=CC=C2

InChI

InChIKey=DQMZLTXERSFNPB-UHFFFAOYSA-N

InChI=1S/C12H14N2O2/c1-2-12(9-6-4-3-5-7-9)10(15)13-8-14-11(12)16/h3-7H,2,8H2,1H3,(H,13,15)(H,14,16)

HIDE SMILES / InChI

Molecular Formula	C12H14N2O2
Molecular Weight	218.2518
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:04:39 UTC 2023` Edited by `admin` on `Fri Dec 15 15:04:39 UTC 2023`
Record UNII	13AFD7670Q
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

PRIMIDONE

Official Name

English

PRIMIDONE [VANDF]

Common Name

English

primidone [INN]

Common Name

English

4,6(1H,5H)-PYRIMIDINEDIONE, 5-ETHYLDIHYDRO-5-PHENYL-

Systematic Name

English

PRIMIDONE [IARC]

Common Name

English

Primidone [WHO-DD]

Common Name

English

PRIMACLONE

Common Name

English

PRIMIDONE [MART.]

Common Name

English

MYSOLINE

Brand Name

English

PRIMIDONE [EP MONOGRAPH]

Common Name

English

LEPIMIDIN

Common Name

English

RESIMATIL

Common Name

English

PRIMIDONE [EP IMPURITY]

Common Name

English

NSC-41701

Code

English

PRIMIDONE [HSDB]

Common Name

English

PRIMIDONE [USP-RS]

Common Name

English

PRIMIDONE [ORANGE BOOK]

Common Name

English

PRIMIDONE [USP MONOGRAPH]

Common Name

English

5-Ethyldihydro-5-phenyl-4,6(1H,5H)-pyrimidinedione

Systematic Name

English

PRIMIDONE [MI]

Common Name

English

PRIMIDONE [GREEN BOOK]

Common Name

English

PRIMIDONE [JAN]

Common Name

English

Classification Tree Code System Code

WHO-VATC

QN03AA03

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

NCI_THESAURUS

C67084

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

WHO-ATC

N03AA03

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

NDF-RT

N0000008486

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

LIVERTOX

NBK548512

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

CFR

21 CFR 862.3680

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

NDF-RT

N0000175753

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

NCI_THESAURUS

C264

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

CFR

21 CFR 520.1900

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

Code System Code Type Description

IUPHAR

5338

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

PRIMARY

EPA CompTox

DTXSID7023510

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

PRIMARY

DRUG BANK

DB00794

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

PRIMARY

MERCK INDEX

m9135

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

PRIMARY

Merck Index

NSC

41701

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

PRIMARY

PUBCHEM

4909

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

PRIMARY

CHEBI

8412

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

PRIMARY

RXCUI

8691

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

PRIMARY

RxNorm

EVMPD

SUB10045MIG

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

PRIMARY

ECHA (EC/EINECS)

204-737-0

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

PRIMARY

FDA UNII

13AFD7670Q

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

PRIMARY

LACTMED

Primidone

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

PRIMARY

ChEMBL

CHEMBL856

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

PRIMARY

SMS_ID

100000081656

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

PRIMARY

INN

248

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

PRIMARY

WIKIPEDIA

PRIMIDONE

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

PRIMARY

CAS

125-33-7

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

PRIMARY

DRUG CENTRAL

2267

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

PRIMARY

RS_ITEM_NUM

1562000

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

PRIMARY

MESH

D011324

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

PRIMARY

NCI_THESAURUS

C47686

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

PRIMARY

DAILYMED

13AFD7670Q

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

PRIMARY

HSDB

3169

Created by admin on Fri Dec 15 15:04:39 UTC 2023 , Edited by admin on Fri Dec 15 15:04:39 UTC 2023

PRIMARY

Related Record Type Details


					PUO0521HZV

CYTOCHROME P450 3A4

METABOLIC ENZYME -> INDUCER


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Amount:

Related Record Type Details


					67CFD7341W

PHENYLETHYLMALONAMIDE

METABOLITE -> PARENT

Comments:

Metabolite to parent drug ratio in non-uraemic human plasma.

Interaction Type:

METABOLITE TO PARENT DRUG RATIO

Qualification:

PLASMA; URINE

Amount:


					YQE403BP4D

METABOLITE -> PARENT

Comments:

Metabolite to parent drug ratio in non-uraemic human plasma.

Interaction Type:

METABOLITE TO PARENT DRUG RATIO

Qualification:

PLASMA; URINE

Amount:


					YQE403BP4D

METABOLITE -> PARENT

Comments:

Percent of dose excreted in urine as metabolite. Primidone is converted in man to phenobarbitone.

Interaction Type:

AMOUNT EXCRETED

Qualification:

URINE

Amount:

Related Record Type Details


					YQE403BP4D

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					AQS5J8A5GJ

PHENYLPROPYLPRIMIDONE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					E1334R6OMW

CIOBUTIDE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					S7S079H2C2

2-PHENYLBUTYRIC ACID

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					67CFD7341W

PHENYLETHYLMALONAMIDE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					J95WO7W7D4

2-PHENYLBUTYRAMIDE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:

Related Record Type Details


					13AFD7670Q

PRIMIDONE

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Volume of Distribution	PHARMACOKINETIC				Population PHARMACOKINETIC

Biological Half-life	PHARMACOKINETIC				Elimination PHARMACOKINETIC Elimination PHARMACOKINETIC