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Details

Stereochemistry ACHIRAL
Molecular Formula C12H12N2O3
Molecular Weight 232.2353
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PHENOBARBITAL

SMILES

CCC1(C(=O)NC(=O)NC1=O)C2=CC=CC=C2

InChI

InChIKey=DDBREPKUVSBGFI-UHFFFAOYSA-N
InChI=1S/C12H12N2O3/c1-2-12(8-6-4-3-5-7-8)9(15)13-11(17)14-10(12)16/h3-7H,2H2,1H3,(H2,13,14,15,16,17)

HIDE SMILES / InChI
Molecular Formula C12H12N2O3
Molecular Weight 232.2353
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
123738
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:27:44 UTC 2023
Edited
by admin
on Fri Dec 15 16:27:44 UTC 2023
Record UNII
YQE403BP4D
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PHENOBARBITAL
EP   HSDB   INN   MART.   MI   USP   VANDF   WHO-DD   WHO-IP  
INN  
Official Name English
PHENOBARBITALUM
HPUS   WHO-IP LATIN  
Common Name English
TEDRAL SUSPENSION
Common Name English
phenobarbital [INN]
Common Name English
THEOPHED
Common Name English
GARDEPANYL
Common Name English
PHENOBARBITAL [USP MONOGRAPH]
Common Name English
PHENOBARBITAL [EP MONOGRAPH]
Common Name English
LUMINAL
Brand Name English
PHENOBARBITAL [JAN]
Common Name English
5-Ethyl-5-phenylbarbituric acid
Systematic Name English
5-ETHYL-5-PHENYLPYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE
Systematic Name English
2,4,6(1H,3H,5H)-PYRIMIDINETRIONE, 5-ETHYL-5-PHENYL-
Systematic Name English
NSC-9848
Code English
METHYLPHENOBARBITAL IMPURITY A [EP IMPURITY]
Common Name English
PHENOBARBITAL [WHO-IP]
Common Name English
PHENOBARBITAL CIV [USP-RS]
Common Name English
PRIMATENE
Common Name English
PRIMIDONE IMPURITY B [EP IMPURITY]
Common Name English
VERSOMNAL
Common Name English
Phenobarbital [WHO-DD]
Common Name English
PHENOBARBITAL [MART.]
Common Name English
GARDENAL
Brand Name English
PHENOBARBITAL CIV
USP-RS  
Common Name English
PHENOBARBITONE
Common Name English
PHENOBARBITALUM [HPUS]
Common Name English
PHENOBARBITAL [IARC]
Common Name English
PHENOBARBITAL [MI]
Common Name English
TRIPHENATOL
Common Name English
PHENOBARBITALUM [WHO-IP LATIN]
Common Name English
TEDRIGEN
Common Name English
PHENOBARBITAL [EP IMPURITY]
Common Name English
NSC-128143
Code English
SEDOPHEN
Common Name English
TEDRAL
Common Name English
PHENOBARBITAL [HSDB]
Common Name English
Classification Tree Code System Code
WHO-VATC QN03AA02
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
CFR 21 CFR 1308.22
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
NCI_THESAURUS C264
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
WHO-ATC N03AA02
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 05
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
EPA PESTICIDE CODE 600122
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
FDA ORPHAN DRUG 725519
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
FDA ORPHAN DRUG 703819
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
FDA ORPHAN DRUG 601717
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
LIVERTOX NBK548269
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
NCI_THESAURUS C67084
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
IARC Phenobarbital
DEA NO. 2285
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
CFR 21 CFR 862.3660
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
Code System Code Type Description
IUPHAR
2804
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
PRIMARY
DRUG CENTRAL
2134
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
PRIMARY
NCI_THESAURUS
C739
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
PRIMARY
WIKIPEDIA
PHENOBARBITAL
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
PRIMARY
RS_ITEM_NUM
1524001
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
PRIMARY
ECHA (EC/EINECS)
200-007-0
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
PHENOBARBITAL
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
PRIMARY Description: Colourless crystals or a white, crystalline powder; odourless. Solubility: Soluble in about 1100 parts of water, in about 10 parts of ethanol (~750 g/l) TS and in about 15 parts of ether R. Category: Hypnotic; sedative; anticonvulsant. Storage: Phenobarbital should be kept in a well-closed container. Additional information: Phenobarbital may exhibit polymorphism. Definition: Phenobarbital contains not less than 98.0% and not more than 101.0% of C12H12N2O3, calculated with reference tothe dried substance.
SMS_ID
100000090330
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
PRIMARY
CHEBI
8069
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
PRIMARY
DAILYMED
YQE403BP4D
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
PRIMARY
LACTMED
Phenobarbital
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
PRIMARY
EPA CompTox
DTXSID5021122
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
PRIMARY
MERCK INDEX
m8622
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
PRIMARY Merck Index
CHEBI
28918
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
PRIMARY
NSC
9848
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
PRIMARY
MESH
D010634
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
PRIMARY
HSDB
3157
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
PRIMARY
ChEMBL
CHEMBL40
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
PRIMARY
FDA UNII
YQE403BP4D
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
PRIMARY
DRUG BANK
DB01174
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
PRIMARY
PUBCHEM
4763
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
PRIMARY
EVMPD
SUB09770MIG
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
PRIMARY
NSC
128143
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
PRIMARY
CAS
50-06-6
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
PRIMARY
RXCUI
8134
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
PRIMARY RxNorm
INN
414
Created by admin on Fri Dec 15 16:27:44 UTC 2023 , Edited by admin on Fri Dec 15 16:27:44 UTC 2023
PRIMARY
Related Record Type Details
CYTOCHROME P450 2C9
METABOLIC ENZYME -> INDUCER
CYTOCHROME P450 3A4
METABOLIC ENZYME -> INDUCER
Structure of PHENOBARBITAL
BASIS OF STRENGTH->SUBSTANCE
ASSAY (TITRATION)
EP
URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 2B7
METABOLIC ENZYME -> INDUCER
Structure of Phenobarbital quinine
SALT/SOLVATE -> PARENT
Structure of PHENOBARBITAL SODIUM
SALT/SOLVATE -> PARENT
Structure of BARBEXACLONE
SALT/SOLVATE -> PARENT
CYTOCHROME P450 2B6
METABOLIC ENZYME -> INDUCER
Structure of PHENOBARBITAL, (ETHYL-D5)-
LABELED -> NON-LABELED
PLASMA PROTEIN FRACTION (HUMAN)
BINDER->LIGAND
CYTOCHROME P450 2C8
METABOLIC ENZYME -> INDUCER
Structure of PHENOBARBITAL
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
USP
Structure of PHENOBARBITAL CALCIUM
SALT/SOLVATE -> PARENT
Structure of MAGNESIUM PHENOBARBITAL
SALT/SOLVATE -> PARENT
Related Record Type Details
Structure of PRIMIDONE
PARENT -> METABOLITE
Metabolite to parent drug ratio in non-uraemic human plasma.
METABOLITE TO PARENT DRUG RATIO
PLASMA; URINE
Structure of MEPHOBARBITAL
PARENT -> METABOLITE
Related Record Type Details
Structure of PRIMIDONE
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of MEPHOBARBITAL
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of PHENYLMETHYLBARBITURIC ACID
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of 5-ETHYL-2,6-DIIMINO-5-PHENYLTETRAHYDROPYRIMIDIN-4(1H)-ONE, (5RS)-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 5-ETHYL-6-IMINO-5-PHENYLDIHYDROPYRIMIDINE-2,4(1H,3H)-DIONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of PRIMIDONE
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Related Record Type Details
Structure of PHENOBARBITAL
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Biological Half-life PHARMACOKINETIC
Structure of PHENOBARBITAL
Elimination
PHARMACOKINETIC
Elimination
PHARMACOKINETIC
Elimimation
PHARMACOKINETIC
Elimination
PHARMACOKINETIC
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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