TRANDOLAPRIL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C24H34N2O5
Molecular Weight	430.5372
Optical Activity	UNSPECIFIED
Defined Stereocenters	5 / 5
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TRANDOLAPRIL

Structure Search

SMILES

[H][C@@]12C[C@H](N(C(=O)[C@H](C)N[C@@H](CCC3=CC=CC=C3)C(=O)OCC)[C@@]1([H])CCCC2)C(O)=O

InChI

InChIKey=VXFJYXUZANRPDJ-WTNASJBWSA-N

InChI=1S/C24H34N2O5/c1-3-31-24(30)19(14-13-17-9-5-4-6-10-17)25-16(2)22(27)26-20-12-8-7-11-18(20)15-21(26)23(28)29/h4-6,9-10,16,18-21,25H,3,7-8,11-15H2,1-2H3,(H,28,29)/t16-,18+,19-,20-,21-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C24H34N2O5
Molecular Weight	430.5372
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	5 / 5
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:43:47 UTC 2023` Edited by `admin` on `Fri Dec 15 15:43:47 UTC 2023`
Record UNII	1T0N3G9CRC
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TRANDOLAPRIL

Official Name

English

TRANDOLAPRIL [USP-RS]

Common Name

English

TRANDOLAPRIL [VANDF]

Common Name

English

TRANDOLAPRIL [JAN]

Common Name

English

1H-INDOLE-2-CARBOXYLIC ACID, OCTAHYDRO N-((2S)-1-ETHOXY-1-OXO-4-PHENYLBUTAN-2-YL)-1-ALANYL (2S,3AR,7AS)

Common Name

English

TRANDOLAPRIL [EP MONOGRAPH]

Common Name

English

TRANDOLAPRIL [USP MONOGRAPH]

Common Name

English

TRANDOLAPRIL [MI]

Common Name

English

(2S,3aR,7aS)-1-[(S)-N-[(S)-1-Carboxy-3-phenylpropyl]alanyl]hexahydro-2-indolinecarboxylic acid, 1-ethyl ester

Common Name

English

NSC-758939

Code

English

TRANDOLAPRIL [ORANGE BOOK]

Common Name

English

TARKA COMPONENT TRANDOLAPRIL

Common Name

English

TRANDOLAPRIL COMPONENT OF TARKA

Common Name

English

TRANDOLAPRIL [MART.]

Common Name

English

RU 44570

Code

English

MAVIK

Brand Name

English

Trandolapril [WHO-DD]

Common Name

English

trandolapril [INN]

Common Name

English

RU-44570

Code

English

Classification Tree Code System Code

WHO-VATC

QC09AA10

Created by admin on Fri Dec 15 15:43:47 UTC 2023 , Edited by admin on Fri Dec 15 15:43:47 UTC 2023

WHO-ATC

C09AA10

Created by admin on Fri Dec 15 15:43:47 UTC 2023 , Edited by admin on Fri Dec 15 15:43:47 UTC 2023

LIVERTOX

NBK548682

Created by admin on Fri Dec 15 15:43:47 UTC 2023 , Edited by admin on Fri Dec 15 15:43:47 UTC 2023

NCI_THESAURUS

C247

Created by admin on Fri Dec 15 15:43:47 UTC 2023 , Edited by admin on Fri Dec 15 15:43:47 UTC 2023

WHO-VATC

QC09BB10

Created by admin on Fri Dec 15 15:43:47 UTC 2023 , Edited by admin on Fri Dec 15 15:43:47 UTC 2023

NDF-RT

N0000175562

Created by admin on Fri Dec 15 15:43:47 UTC 2023 , Edited by admin on Fri Dec 15 15:43:47 UTC 2023

WHO-ATC

C09BB10

Created by admin on Fri Dec 15 15:43:47 UTC 2023 , Edited by admin on Fri Dec 15 15:43:47 UTC 2023

NDF-RT

N0000000181

Created by admin on Fri Dec 15 15:43:47 UTC 2023 , Edited by admin on Fri Dec 15 15:43:47 UTC 2023

Code System Code Type Description

NCI_THESAURUS

C61978

Created by admin on Fri Dec 15 15:43:47 UTC 2023 , Edited by admin on Fri Dec 15 15:43:47 UTC 2023

PRIMARY

CHEBI

9649

Created by admin on Fri Dec 15 15:43:47 UTC 2023 , Edited by admin on Fri Dec 15 15:43:47 UTC 2023

PRIMARY

RS_ITEM_NUM

1672687

Created by admin on Fri Dec 15 15:43:47 UTC 2023 , Edited by admin on Fri Dec 15 15:43:47 UTC 2023

PRIMARY

ChEMBL

CHEMBL1519

Created by admin on Fri Dec 15 15:43:47 UTC 2023 , Edited by admin on Fri Dec 15 15:43:47 UTC 2023

PRIMARY

NSC

758939

Created by admin on Fri Dec 15 15:43:47 UTC 2023 , Edited by admin on Fri Dec 15 15:43:47 UTC 2023

PRIMARY

DAILYMED

1T0N3G9CRC

Created by admin on Fri Dec 15 15:43:47 UTC 2023 , Edited by admin on Fri Dec 15 15:43:47 UTC 2023

PRIMARY

DRUG BANK

DB00519

Created by admin on Fri Dec 15 15:43:47 UTC 2023 , Edited by admin on Fri Dec 15 15:43:47 UTC 2023

PRIMARY

INN

5746

Created by admin on Fri Dec 15 15:43:47 UTC 2023 , Edited by admin on Fri Dec 15 15:43:47 UTC 2023

PRIMARY

PUBCHEM

5484727

Created by admin on Fri Dec 15 15:43:47 UTC 2023 , Edited by admin on Fri Dec 15 15:43:47 UTC 2023

PRIMARY

DRUG CENTRAL

2712

Created by admin on Fri Dec 15 15:43:47 UTC 2023 , Edited by admin on Fri Dec 15 15:43:47 UTC 2023

PRIMARY

CAS

87679-37-6

Created by admin on Fri Dec 15 15:43:47 UTC 2023 , Edited by admin on Fri Dec 15 15:43:47 UTC 2023

PRIMARY

SMS_ID

100000092313

Created by admin on Fri Dec 15 15:43:47 UTC 2023 , Edited by admin on Fri Dec 15 15:43:47 UTC 2023

PRIMARY

EPA CompTox

DTXSID2023692

Created by admin on Fri Dec 15 15:43:47 UTC 2023 , Edited by admin on Fri Dec 15 15:43:47 UTC 2023

PRIMARY

RXCUI

38454

Created by admin on Fri Dec 15 15:43:47 UTC 2023 , Edited by admin on Fri Dec 15 15:43:47 UTC 2023

PRIMARY

RxNorm

MESH

C052035

Created by admin on Fri Dec 15 15:43:47 UTC 2023 , Edited by admin on Fri Dec 15 15:43:47 UTC 2023

PRIMARY

WIKIPEDIA

TRANDOLAPRIL

Created by admin on Fri Dec 15 15:43:47 UTC 2023 , Edited by admin on Fri Dec 15 15:43:47 UTC 2023

PRIMARY

LACTMED

Trandolapril

Created by admin on Fri Dec 15 15:43:47 UTC 2023 , Edited by admin on Fri Dec 15 15:43:47 UTC 2023

PRIMARY

FDA UNII

1T0N3G9CRC

Created by admin on Fri Dec 15 15:43:47 UTC 2023 , Edited by admin on Fri Dec 15 15:43:47 UTC 2023

PRIMARY

IUPHAR

6453

Created by admin on Fri Dec 15 15:43:47 UTC 2023 , Edited by admin on Fri Dec 15 15:43:47 UTC 2023

PRIMARY

EVMPD

SUB11212MIG

Created by admin on Fri Dec 15 15:43:47 UTC 2023 , Edited by admin on Fri Dec 15 15:43:47 UTC 2023

PRIMARY

MERCK INDEX

m10999

Created by admin on Fri Dec 15 15:43:47 UTC 2023 , Edited by admin on Fri Dec 15 15:43:47 UTC 2023

PRIMARY

Merck Index

Related Record Type Details


					1T0N3G9CRC

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (HPLC)

Qualification:

EP

Amount:


					3EY8XK2J4T

TRANDOLAPRIL HYDROCHLORIDE

SALT/SOLVATE -> PARENT


					1T0N3G9CRC

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (HPLC)

Qualification:

USP

Amount:


					HPN66MJEK8

LIVER CARBOXYLESTERASE 1

METABOLIC ENZYME -> SUBSTRATE

Amount:

Related Record Type Details


					RR6866VL0O

METABOLITE ACTIVE -> PRODRUG

Related Record Type Details


					4768A319U6

RU-46178

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					7U47129S2I

TRANDOLAPRIL EPIMER, (2R-CARBOXYLIC ACID)-

IMPURITY -> PARENT

Comments:

UNSPECIFIED

Qualification:

EP


					RR6866VL0O

IMPURITY -> PARENT

Comments:

UNSPECIFIED

Qualification:

EP


					F4APT9Y29T

HEXAHYDROTRANDOLAPRIL

IMPURITY -> PARENT

Comments:

For the calculation of contents, multiply the peak areas by 2.2

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					F4APT9Y29T

HEXAHYDROTRANDOLAPRIL

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					AB6C8K02JG

TRANDOLAPRILAT ISOPROPYL ESTER

IMPURITY -> PARENT

Comments:

UNSPECIFIED

Qualification:

EP


					0OVI46O201

TRANDOLAPRILAT METHYL ESTER

IMPURITY -> PARENT

Comments:

UNSPECIFIED

Qualification:

EP


					4768A319U6

RU-46178

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount: