MEXILETINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C11H17NO
Molecular Weight	179.2588
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of MEXILETINE

Structure Search

SMILES

CC(N)COC1=C(C)C=CC=C1C

InChI

InChIKey=VLPIATFUUWWMKC-UHFFFAOYSA-N

InChI=1S/C11H17NO/c1-8-5-4-6-9(2)11(8)13-7-10(3)12/h4-6,10H,7,12H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C11H17NO
Molecular Weight	179.2588
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:46:00 UTC 2023` Edited by `admin` on `Fri Dec 15 18:46:00 UTC 2023`
Record UNII	1U511HHV4Z
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

MEXILETINE

Official Name

English

MEXILETINE [MI]

Common Name

English

DL-MEXILETINE

Common Name

English

(RS)-MEXILETINE

Common Name

English

1-METHYL-2-(2,6-XYLYLOXY)ETHYLAMINE

Systematic Name

English

(±)-MEXILETINE

Common Name

English

(±)-2-AMINO-1-(2',6'-DIMETHYLPHENOXY)PROPANE

Common Name

English

1-(2,6-DIMETHYLPHENOXY)-2-PROPANAMINE

Systematic Name

English

MEXILETINE [VANDF]

Common Name

English

1-(2',6'-DIMETHYLPHENOXY)-2-AMINOPROPANE

Common Name

English

Mexiletine [WHO-DD]

Common Name

English

ETHYLAMINE, 1-METHYL-2-(2,6-XYLYLOXY)-

Systematic Name

English

mexiletine [INN]

Common Name

English

2-PROPANAMINE, 1-(2,6-DIMETHYLPHENOXY)-

Systematic Name

English

(2-((2,6-DIMETHYLPHENYL)OXY)-1-METHYLETHYL)AMINE

Systematic Name

English

2-AMINO-1-(2,6-DIMETHYLPHENOXY)PROPANE

Systematic Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

728219

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

WHO-ATC

C01BB02

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

NCI_THESAURUS

C93038

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

NCI_THESAURUS

C47793

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

FDA ORPHAN DRUG

314410

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

WHO-VATC

QC01BB02

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

NDF-RT

N0000175426

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

Code System Code Type Description

WIKIPEDIA

MEXILETINE

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

PRIMARY

SMS_ID

100000081179

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

PRIMARY

MESH

D008801

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

PRIMARY

PUBCHEM

4178

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

PRIMARY

FDA UNII

1U511HHV4Z

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

PRIMARY

MERCK INDEX

m7518

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

PRIMARY

Merck Index

CAS

31828-71-4

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

PRIMARY

LACTMED

Mexiletine

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

PRIMARY

DRUG BANK

DB00379

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

PRIMARY

CHEBI

6916

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

PRIMARY

CAS

61079-93-4

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

SUPERSEDED

DRUG CENTRAL

1794

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

PRIMARY

ChEMBL

CHEMBL558

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

PRIMARY

EPA CompTox

DTXSID8048446

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

PRIMARY

CAS

128942-27-8

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

SUPERSEDED

NCI_THESAURUS

C62047

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

PRIMARY

CAS

718619-78-4

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

SUPERSEDED

RXCUI

6926

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

PRIMARY

RxNorm

INN

3262

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

PRIMARY

DAILYMED

1U511HHV4Z

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

PRIMARY

IUPHAR

2629

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

PRIMARY

EVMPD

SUB08931MIG

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

PRIMARY

ECHA (EC/EINECS)

250-825-7

Created by admin on Fri Dec 15 18:46:01 UTC 2023 , Edited by admin on Fri Dec 15 18:46:01 UTC 2023

PRIMARY

Related Record Type Details


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					1U511HHV4Z

EXCRETED UNCHANGED

Qualification:

URINE

Amount:


					606D60IS38

MEXILETINE HYDROCHLORIDE

SALT/SOLVATE -> PARENT


					482M00274D

OCT-2

TRANSPORTER -> INHIBITOR

Related Record Type Details


					0G7UJL9QZJ

(2-(2-AMINOPROPOXY)-3-METHYLPHENYL)METHANOL

METABOLITE ACTIVE -> PARENT


					SA6FY9NRV3

1-(2-(HYDROXYMETHYL)-6-METHYLPHENOXY)PROPAN-2-OL

METABOLITE -> PARENT


					D9M8AQ3NDJ

4-(2-AMINOPROPOXY)-3,5-DIMETHYLPHENOL

METABOLITE ACTIVE -> PARENT

Related Record Type Details


					1U511HHV4Z

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Tmax	PHARMACOKINETIC

Biological Half-life	PHARMACOKINETIC

Volume of Distribution	PHARMACOKINETIC