PIRENZEPINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C19H21N5O2
Molecular Weight	351.4023
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN1CCN(CC(=O)N2C3=CC=CC=C3C(=O)NC4=C2N=CC=C4)CC1

InChI

InChIKey=RMHMFHUVIITRHF-UHFFFAOYSA-N

InChI=1S/C19H21N5O2/c1-22-9-11-23(12-10-22)13-17(25)24-16-7-3-2-5-14(16)19(26)21-15-6-4-8-20-18(15)24/h2-8H,9-13H2,1H3,(H,21,26)

HIDE SMILES / InChI

Molecular Formula	C19H21N5O2
Molecular Weight	351.4023
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:10:31 UTC 2023` Edited by `admin` on `Sat Dec 16 17:10:31 UTC 2023`
Record UNII	3G0285N20N
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PIRENZEPINE

Official Name

English

PIRENZEPINE [MI]

Common Name

English

pirenzepine [INN]

Common Name

English

6H-PYRIDO(2,3-B)(1,4)BENZODIAZEPIN-6-ONE, 5,11-DIHYDRO-11-((4-METHYL-1-PIPERAZINYL)ACETYL)-

Systematic Name

English

ACI-91

Code

English

PIRENZEPINE [VANDF]

Common Name

English

11-((4-METHYL-1-PIPERAZINYL)ACETYL)-5,11-DIHYDRO-6H-PYRIDO(2,3-B)(1,4)BENZODIAZEPIN-6-ONE

Systematic Name

English

Pirenzepine [WHO-DD]

Common Name

English

5,11-DIHYDRO-11-((4-METHYL-1-PIPERAZINYL)ACETYL)-6H-PYRIDO(2,3-B)(1,4)BENZODIAZEPIN-6-ONE

Systematic Name

English

WST-057

Code

English

Classification Tree Code System Code

WHO-ATC

A02BX03

Created by admin on Sat Dec 16 17:10:32 UTC 2023 , Edited by admin on Sat Dec 16 17:10:32 UTC 2023

NCI_THESAURUS

C29704

Created by admin on Sat Dec 16 17:10:33 UTC 2023 , Edited by admin on Sat Dec 16 17:10:33 UTC 2023

WHO-VATC

QA02BX03

Created by admin on Sat Dec 16 17:10:33 UTC 2023 , Edited by admin on Sat Dec 16 17:10:33 UTC 2023

Code System Code Type Description

MESH

D010890

Created by admin on Sat Dec 16 17:10:33 UTC 2023 , Edited by admin on Sat Dec 16 17:10:33 UTC 2023

PRIMARY

CAS

28797-61-7

Created by admin on Sat Dec 16 17:10:32 UTC 2023 , Edited by admin on Sat Dec 16 17:10:32 UTC 2023

PRIMARY

SMS_ID

100000081663

Created by admin on Sat Dec 16 17:10:33 UTC 2023 , Edited by admin on Sat Dec 16 17:10:33 UTC 2023

PRIMARY

DRUG CENTRAL

2200

Created by admin on Sat Dec 16 17:10:33 UTC 2023 , Edited by admin on Sat Dec 16 17:10:33 UTC 2023

PRIMARY

DRUG BANK

DB00670

Created by admin on Sat Dec 16 17:10:32 UTC 2023 , Edited by admin on Sat Dec 16 17:10:32 UTC 2023

PRIMARY

PUBCHEM

4848

Created by admin on Sat Dec 16 17:10:33 UTC 2023 , Edited by admin on Sat Dec 16 17:10:33 UTC 2023

PRIMARY

MERCK INDEX

m8874

Created by admin on Sat Dec 16 17:10:33 UTC 2023 , Edited by admin on Sat Dec 16 17:10:33 UTC 2023

PRIMARY

Merck Index

WIKIPEDIA

PIRENZEPINE

Created by admin on Sat Dec 16 17:10:33 UTC 2023 , Edited by admin on Sat Dec 16 17:10:33 UTC 2023

PRIMARY

EPA CompTox

DTXSID7023487

Created by admin on Sat Dec 16 17:10:33 UTC 2023 , Edited by admin on Sat Dec 16 17:10:33 UTC 2023

PRIMARY

IUPHAR

328

Created by admin on Sat Dec 16 17:10:33 UTC 2023 , Edited by admin on Sat Dec 16 17:10:33 UTC 2023

PRIMARY

FDA UNII

3G0285N20N

Created by admin on Sat Dec 16 17:10:33 UTC 2023 , Edited by admin on Sat Dec 16 17:10:33 UTC 2023

PRIMARY

ChEMBL

CHEMBL9967

Created by admin on Sat Dec 16 17:10:32 UTC 2023 , Edited by admin on Sat Dec 16 17:10:32 UTC 2023

PRIMARY

NCI_THESAURUS

C76002

Created by admin on Sat Dec 16 17:10:33 UTC 2023 , Edited by admin on Sat Dec 16 17:10:33 UTC 2023

PRIMARY

RXCUI

8352

Created by admin on Sat Dec 16 17:10:33 UTC 2023 , Edited by admin on Sat Dec 16 17:10:33 UTC 2023

PRIMARY

RxNorm

CHEBI

8247

Created by admin on Sat Dec 16 17:10:32 UTC 2023 , Edited by admin on Sat Dec 16 17:10:32 UTC 2023

PRIMARY

INN

3476

Created by admin on Sat Dec 16 17:10:33 UTC 2023 , Edited by admin on Sat Dec 16 17:10:33 UTC 2023

PRIMARY

EVMPD

SUB09904MIG

Created by admin on Sat Dec 16 17:10:32 UTC 2023 , Edited by admin on Sat Dec 16 17:10:32 UTC 2023

PRIMARY

ECHA (EC/EINECS)

249-228-4

Created by admin on Sat Dec 16 17:10:33 UTC 2023 , Edited by admin on Sat Dec 16 17:10:33 UTC 2023

PRIMARY

Related Record Type Details


					10YM403FLS

PIRENZEPINE HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Amount:


					TR66JMA2FS

PIRENZEPINE HYDROCHLORIDE MONOHYDRATE

SALT/SOLVATE -> PARENT

Amount:


					KG2XA994SN

[3H]Pirenzepine

LABELED -> NON-LABELED

Amount:


					W3JX5KZ4V2

MUSCARINIC ACETYLCHOLINE RECEPTOR M3

TARGET -> INHIBITOR

Interaction Type:

BINDING

Qualification:

IC50

Amount:


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					V23K99CV7G

MUSCARINIC ACETYLCHOLINE RECEPTOR M1

TARGET -> INHIBITOR

Comments:

Pirenzepine is a selective muscarinic M1 receptor antagonist

Amount:


					5Q0390016E

PIRENZEPINE MONOHYDRATE

SOLVATE->ANHYDROUS

Amount:


					U87RX375T5

MUSCARINIC ACETYLCHOLINE RECEPTOR M2

OFF-TARGET->INHIBITOR

Qualification:

IC50

Amount:

Related Record Type Details


					3G0285N20N

PIRENZEPINE

ACTIVE MOIETY

Amount: