Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C19H17N5O3 |
| Molecular Weight | 363.37 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NC1=NC2=C(O1)C=CC(=C2)C3=CN4C(=CN=C4C=C3)C(=O)N5CCOCC5
InChI
InChIKey=BLGWHBSBBJNKJO-UHFFFAOYSA-N
InChI=1S/C19H17N5O3/c20-19-22-14-9-12(1-3-16(14)27-19)13-2-4-17-21-10-15(24(17)11-13)18(25)23-5-7-26-8-6-23/h1-4,9-11H,5-8H2,(H2,20,22)
| Molecular Formula | C19H17N5O3 |
| Molecular Weight | 363.37 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 05:27:12 UTC 2023
by
admin
on
Sat Dec 16 05:27:12 UTC 2023
|
| Record UNII |
43J9Q56T3W
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
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Code | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C129825
Created by
admin on Sat Dec 16 05:27:12 UTC 2023 , Edited by admin on Sat Dec 16 05:27:12 UTC 2023
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NCI_THESAURUS |
C2152
Created by
admin on Sat Dec 16 05:27:12 UTC 2023 , Edited by admin on Sat Dec 16 05:27:12 UTC 2023
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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1268454-23-4
Created by
admin on Sat Dec 16 05:27:12 UTC 2023 , Edited by admin on Sat Dec 16 05:27:12 UTC 2023
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PRIMARY | |||
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1428967-74-1
Created by
admin on Sat Dec 16 05:27:12 UTC 2023 , Edited by admin on Sat Dec 16 05:27:12 UTC 2023
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NO STRUCTURE GIVEN | |||
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C98844
Created by
admin on Sat Dec 16 05:27:12 UTC 2023 , Edited by admin on Sat Dec 16 05:27:12 UTC 2023
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PRIMARY | |||
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CHEMBL3545379
Created by
admin on Sat Dec 16 05:27:12 UTC 2023 , Edited by admin on Sat Dec 16 05:27:12 UTC 2023
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PRIMARY | |||
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70798655
Created by
admin on Sat Dec 16 05:27:12 UTC 2023 , Edited by admin on Sat Dec 16 05:27:12 UTC 2023
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PRIMARY | |||
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100000174654
Created by
admin on Sat Dec 16 05:27:12 UTC 2023 , Edited by admin on Sat Dec 16 05:27:12 UTC 2023
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PRIMARY | |||
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43J9Q56T3W
Created by
admin on Sat Dec 16 05:27:12 UTC 2023 , Edited by admin on Sat Dec 16 05:27:12 UTC 2023
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PRIMARY | |||
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DB14935
Created by
admin on Sat Dec 16 05:27:12 UTC 2023 , Edited by admin on Sat Dec 16 05:27:12 UTC 2023
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PRIMARY | |||
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CHEMBL3545055
Created by
admin on Sat Dec 16 05:27:12 UTC 2023 , Edited by admin on Sat Dec 16 05:27:12 UTC 2023
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PRIMARY | |||
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10369
Created by
admin on Sat Dec 16 05:27:12 UTC 2023 , Edited by admin on Sat Dec 16 05:27:12 UTC 2023
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PRIMARY |
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|---|---|---|---|---|
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Selective, oral bioavailable PI3Kα isoform inhibitor s more than 100-fold selective than other class I
PI3K isoforms and mTOR as well as a high degree of selectivity against a large panel of protein kinases with potential antitumor activity.
IC50
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ACTIVE MOIETY |
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