TUCOTUZUMAB CELMOLEUKIN

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National Institutes of Health Divider Arrow

NCATS

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 18:31:52 GMT 2025` Edited by `admin` on `Mon Mar 31 18:31:52 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type	IGG1
Sequence Origin	fusion protein of a humanized monoclonal antibody (tucotuzumab) and an interleukin-2 (celmoleukin)
Sequence Type	COMPLETE
Record UNII	4ON7FF680U
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TUCOTUZUMAB CELMOLEUKIN

Official Name

English

EMD 273066

Preferred Name

English

tucotuzumab celmoleukin [INN]

Common Name

English

TUCOTUZUMAB CELMOLEUKIN [USAN]

Common Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN ANTIGEN 17-1A) (HUMAN-MOUSE MONOCLONAL HUKS-IL2 HEAVY CHAIN) FUSION PROTEIN WITH INTERLEUKIN 2 (HUMAN), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL HUKS-IL2 LIGHT CHAIN, DIMER

Common Name

English

KSA-INTERLEUKIN-2

Code

English

HUKS-IL2

Code

English

EMD-273066

Code

English

Tucotuzumab celmoleukin [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1512

Created by admin on Mon Mar 31 18:31:52 GMT 2025 , Edited by admin on Mon Mar 31 18:31:52 GMT 2025

Code System Code Type Description

NCI_THESAURUS

C2630

Created by admin on Mon Mar 31 18:31:52 GMT 2025 , Edited by admin on Mon Mar 31 18:31:52 GMT 2025

PRIMARY

USAN

OO-23

Created by admin on Mon Mar 31 18:31:52 GMT 2025 , Edited by admin on Mon Mar 31 18:31:52 GMT 2025

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CAS

339986-90-2

Created by admin on Mon Mar 31 18:31:52 GMT 2025 , Edited by admin on Mon Mar 31 18:31:52 GMT 2025

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WIKIPEDIA

Tucotuzumab celmoleukin

Created by admin on Mon Mar 31 18:31:52 GMT 2025 , Edited by admin on Mon Mar 31 18:31:52 GMT 2025

PRIMARY

ChEMBL

CHEMBL2108660

Created by admin on Mon Mar 31 18:31:52 GMT 2025 , Edited by admin on Mon Mar 31 18:31:52 GMT 2025

PRIMARY

SMS_ID

300000022466

Created by admin on Mon Mar 31 18:31:52 GMT 2025 , Edited by admin on Mon Mar 31 18:31:52 GMT 2025

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INN

8652

Created by admin on Mon Mar 31 18:31:52 GMT 2025 , Edited by admin on Mon Mar 31 18:31:52 GMT 2025

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DRUG BANK

DB15402

Created by admin on Mon Mar 31 18:31:52 GMT 2025 , Edited by admin on Mon Mar 31 18:31:52 GMT 2025

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FDA UNII

4ON7FF680U

Created by admin on Mon Mar 31 18:31:52 GMT 2025 , Edited by admin on Mon Mar 31 18:31:52 GMT 2025

PRIMARY

From	To
1_22	1_96
2_22	2_96
3_23	3_87
4_23	4_87
3_133	3_193
4_133	4_193
1_143	1_199
2_143	2_199
1_219	3_213
2_219	4_213
1_225	2_225
1_228	2_228
1_260	1_320
2_260	2_320
1_366	1_424
2_366	2_424
1_504	1_551
2_504	2_551

Related Record Type Details


					68321OQ1A9

EPITHELIAL CELL ADHESION MOLECULE

TARGET -> INHIBITOR

Related Record Type Details


					4ON7FF680U

TUCOTUZUMAB CELMOLEUKIN

ACTIVE MOIETY

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_1] [2_1]		GLUTAMIC ACID		PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL