ENDOTHELIN-1 RECEPTOR

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 01:56:37 GMT 2025` Edited by `admin` on `Wed Apr 02 01:56:37 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	5Q6PN7AC39
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ENDOTHELIN-1 RECEPTOR

Common Name

English

ENDOTHELIN A RECEPTOR

Preferred Name

English

ETA-R

Common Name

English

ETRA

Common Name

English

HET-AR

Common Name

English

ENDOTHELIN RECEPTOR TYPE A

Common Name

English

ET-A

Common Name

English

Code System Code Type Description

WIKIPEDIA

ENDOTHELIN

Created by admin on Wed Apr 02 01:56:37 GMT 2025 , Edited by admin on Wed Apr 02 01:56:37 GMT 2025

PRIMARY

UNIPROT

P25101

Created by admin on Wed Apr 02 01:56:37 GMT 2025 , Edited by admin on Wed Apr 02 01:56:37 GMT 2025

PRIMARY

PHAROS

P25101

Created by admin on Wed Apr 02 01:56:37 GMT 2025 , Edited by admin on Wed Apr 02 01:56:37 GMT 2025

PRIMARY

FDA UNII

5Q6PN7AC39

Created by admin on Wed Apr 02 01:56:37 GMT 2025 , Edited by admin on Wed Apr 02 01:56:37 GMT 2025

PRIMARY

From	To
1_138	1_219

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_9
N	1_42

Related Record Type Details


					HW6NV07QEC

AMBRISENTAN

INHIBITOR -> TARGET


					0066WLJ02E

HUMAN ENDOTHELIN-3

AGONIST -> TARGET

Interaction Type:

BINDING

Qualification:

IC50

Amount:


					96R6F9J2AV

Ro-46-2005

INHIBITOR -> TARGET

Comments:

human smooth muscle cells

Qualification:

IC50

Amount:


					MZI81HV01P

APROCITENTAN

INHIBITOR -> TARGET

Amount:


					9242RO5URM

SPARSENTAN

INHIBITOR -> TARGET

Amount:


					J9QH779MEM

SITAXENTAN

INHIBITOR -> TARGET

Amount:


					2K62B8Z6XF

ENDOTHELIN-1

AGONIST -> TARGET

Interaction Type:

BINDING

Qualification:

IC50

Amount:


					PB6W6L7YPN

ENDOTHELIN-1 I-125

RADIOLIGAND->TARGET

Qualification:

Kd

Amount:


					K3KZN98GF5

Patecibart

INHIBITOR -> TARGET

Amount:


					S2A8YZM151

BQ-123

INHIBITOR -> TARGET

Comments:

Porcine aortic smooth muscle membranes.

Interaction Type:

BINDING

Qualification:

IC50

Amount:


					S5016F5ZH4

EDONENTAN ANHYDROUS

INHIBITOR -> TARGET

Amount:


					64J9J55263

TEZOSENTAN

INHIBITOR -> TARGET

Amount:


					Z9K9Y9WMVL

MACITENTAN

INHIBITOR -> TARGET

Amount:


					3NZ34T0RCS

S-0139 FREE ACID

INHIBITOR -> TARGET


					GV4UZC9M2H

TAK-044 free acid

INHIBITOR -> TARGET

Amount:


					IJ670B0H4A

NEBENTAN

INHIBITOR -> TARGET

Amount:


					V6D7VK2215

ATRASENTAN

INHIBITOR -> TARGET

Amount:


					771E5ELJ7N

FANDOSENTAN

INHIBITOR -> TARGET

Amount:


					3DRR0X4728

CLAZOSENTAN

INHIBITOR -> TARGET

Amount:


					6RW6H4951Z

FELOPRENTAN

INHIBITOR -> TARGET

Amount:


					33JD57L6RW

DARUSENTAN

INHIBITOR -> TARGET

Amount:


					L94KSX715K

AVOSENTAN

INHIBITOR -> TARGET

Amount:


					8054MM4902

ZIBOTENTAN

INHIBITOR -> TARGET

Amount:


					QG16H8A6ZH

ENRASENTAN

INHIBITOR -> TARGET

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL