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Details

Stereochemistry ACHIRAL
Molecular Formula C5H4N4O
Molecular Weight 136.1115
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ALLOPURINOL

SMILES

O=C1N=CNC2=C1C=NN2

InChI

InChIKey=OFCNXPDARWKPPY-UHFFFAOYSA-N
InChI=1S/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10)

HIDE SMILES / InChI
Molecular Formula C5H4N4O
Molecular Weight 136.1115
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Sat Dec 16 18:03:21 UTC 2023
Edited
by admin
on Sat Dec 16 18:03:21 UTC 2023
Record UNII
63CZ7GJN5I
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ALLOPURINOL
EP   HSDB   INN   MART.   MI   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD   WHO-IP  
USAN   INN  
Official Name English
ALLOPURINOL [MART.]
Common Name English
1H-PYRAZOLO(3,4-D)PYRIMIDIN-4-OL
Systematic Name English
ALLOPURINOL [EP IMPURITY]
Common Name English
ALLOPURINOL [WHO-IP]
Common Name English
ZYLOPRIM
Brand Name English
SUSPENDOL
Common Name English
ALLOPURINOL [JAN]
Common Name English
allopurinol [INN]
Common Name English
TAKANARUMIN
Common Name English
NSC-101655
Code English
Allopurinol [WHO-DD]
Common Name English
ALLOPURINOL [ORANGE BOOK]
Common Name English
1,5-Dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
Systematic Name English
BW-56-158
Code English
ALLOPURINOLUM [WHO-IP]
Common Name English
ALLOPURINOL [MI]
Common Name English
ALLOPURINOL [USP-RS]
Common Name English
4H-PYRAZOLO(3,4-D)PYRIMIDIN-4-ONE, 1,5-DIHYDRO-
Systematic Name English
ALLOPURINOL [HSDB]
Common Name English
DUZALLO COMPONENT ALLOPURINOL
Brand Name English
NSC-1390
Code English
ALLOPURINOL [USAN]
Common Name English
ALLOPURINOL [USP MONOGRAPH]
Common Name English
LOPURIN
Brand Name English
BW 56-158
Code English
ALLOPURINOL [EP MONOGRAPH]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C1637
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
WHO-VATC QM04AA51
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 8.2
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
NCI_THESAURUS C921
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
WHO-VATC QM04AA01
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
LIVERTOX NBK548098
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
WHO-ATC M04AA51
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
WHO-ATC M04AA01
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
NDF-RT N0000000206
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
NDF-RT N0000175698
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 2.3
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
Code System Code Type Description
DRUG CENTRAL
124
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
PRIMARY
CAS
184856-42-6
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
SUPERSEDED
DAILYMED
63CZ7GJN5I
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
PRIMARY
CHEBI
40279
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
PRIMARY
NSC
1390
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
PRIMARY
IUPHAR
6795
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
PRIMARY
LACTMED
Allopurinol
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
PRIMARY
NCI_THESAURUS
C224
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
PRIMARY
SMS_ID
100000091907
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
PRIMARY
PUBCHEM
135401907
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
PRIMARY
ChEMBL
CHEMBL1467
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
PRIMARY
MERCK INDEX
m1541
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
PRIMARY Merck Index
CAS
39464-14-7
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
SUPERSEDED
RXCUI
519
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
PRIMARY RxNorm
CAS
22767-92-6
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
SUPERSEDED
ECHA (EC/EINECS)
206-250-9
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
PRIMARY
NSC
101655
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
PRIMARY
WIKIPEDIA
ALLOPURINOL
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
PRIMARY
CAS
315-30-0
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
PRIMARY
HSDB
3004
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
PRIMARY
EVMPD
SUB05338MIG
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
PRIMARY
FDA UNII
63CZ7GJN5I
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
ALLOPURINOL
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
PRIMARY Description: A white or almost white, microcrystalline powder; odourless or almost odourless. Solubility: Very slightly soluble in water and in ethanol (~750 g/l) TS and ether R. Category: Xanthine oxidase inhibitor. Storage: Allopurinol should be kept in a well-closed container. Definition: Allopurinol contains not less than 98.0% and not more than 101.0% of C5H4N4O, calculated with reference to the dried substance.
RS_ITEM_NUM
1013002
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
PRIMARY
INN
1731
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
PRIMARY
MESH
D000493
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
PRIMARY
EPA CompTox
DTXSID4022573
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
PRIMARY
DRUG BANK
DB00437
Created by admin on Sat Dec 16 18:03:23 UTC 2023 , Edited by admin on Sat Dec 16 18:03:23 UTC 2023
PRIMARY
Related Record Type Details
Structure of ALLOPURINOL
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
USP
Structure of ALLOPURINOL SODIUM
SALT/SOLVATE -> PARENT
OAT-2
TRANSPORTER -> SUBSTRATE
Structure of ALLOPURINOL
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
EP
XANTHINE DEHYDROGENASE/OXIDASE
TARGET -> INHIBITOR
Related Record Type Details
Structure of OXYPURINOL
METABOLITE ACTIVE -> PARENT
MAJOR
Related Record Type Details
Structure of HYDRAZINE
IMPURITY -> PARENT
In USP/NF not more than 10 ppm of hydrazine is found
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of ETHYL 5-AMINO-1H-PYRAZOLE-4-CARBOXYLATE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 1H-PYRAZOLE-4-CARBOXAMIDE, 3-AMINO-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 5-FORMYLAMINO-1H-PYRAZOLE-4-CARBOXAMIDE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 5-(4H-1,2,4-TRIAZOL-4-YL)-1H-PYRAZOLE-4-CARBOXAMIDE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 1H-PYRAZOLE-4-CARBOXAMIDE, 3-AMINO-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
ETHYL-3-(2-CARBETHOXY-2-CYANOETHENYL)AMINO-1H-PYRAZOLE-4-CARBOXYLATE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of ETHYL 5-(FORMYLAMINO)-1H-PYRAZOLE-4-CARBOXYLATE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 5-FORMYLAMINO-1H-PYRAZOLE-4-CARBOXAMIDE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of ETHYL 5-(FORMYLAMINO)-1H-PYRAZOLE-4-CARBOXYLATE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 5-(4H-1,2,4-TRIAZOL-4-YL)-1H-PYRAZOLE-4-CARBOXAMIDE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
Structure of ALLOPURINOL
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Volume of Distribution PHARMACOKINETIC
Biological Half-life PHARMACOKINETIC
NIH
NCATS
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