TESAGLITAZAR

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C20H24O7S
Molecular Weight	408.465
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TESAGLITAZAR

Structure Search

SMILES

CCO[C@@H](CC1=CC=C(OCCC2=CC=C(OS(C)(=O)=O)C=C2)C=C1)C(O)=O

InChI

InChIKey=CXGTZJYQWSUFET-IBGZPJMESA-N

InChI=1S/C20H24O7S/c1-3-25-19(20(21)22)14-16-6-8-17(9-7-16)26-13-12-15-4-10-18(11-5-15)27-28(2,23)24/h4-11,19H,3,12-14H2,1-2H3,(H,21,22)/t19-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C20H24O7S
Molecular Weight	408.465
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:24:21 UTC 2023` Edited by `admin` on `Fri Dec 15 16:24:21 UTC 2023`
Record UNII	6734037O3L
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TESAGLITAZAR

Official Name

English

GALIDA

Brand Name

English

AR-H-039242

Code

English

TESAGLITAZAR [USAN]

Common Name

English

BENZENEPROPANOIC ACID,.ALPHA.-ETHOXY-4-(2-(4-((METHYLSULFONYL)OXY)PHENYL)ETHOXY) ,(.ALPHA.S)-

Systematic Name

English

Tesaglitazar [WHO-DD]

Common Name

English

TESAGLITAZAR [MI]

Common Name

English

TESAGLITAZAR [JAN]

Common Name

English

AZ-242

Code

English

AR-H039242XX

Code

English

(2S)-2-Ethoxy-3-[4-[2-[4-[(methylsulfonyl)oxy]phenyl]ethoxy]phenyl]propanoic acid

Systematic Name

English

tesaglitazar [INN]

Common Name

English

BR-44608

Code

English

(S)-2-ETHOXY-3-(4-(2-(4-METHYLSULFONYLOXYPHENYL)ETHOXY)PHENYL)PROPANOIC ACID

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C98233

Created by admin on Fri Dec 15 16:24:21 UTC 2023 , Edited by admin on Fri Dec 15 16:24:21 UTC 2023

Code System Code Type Description

INN

8092

Created by admin on Fri Dec 15 16:24:21 UTC 2023 , Edited by admin on Fri Dec 15 16:24:21 UTC 2023

PRIMARY

MERCK INDEX

m1262

Created by admin on Fri Dec 15 16:24:21 UTC 2023 , Edited by admin on Fri Dec 15 16:24:21 UTC 2023

PRIMARY

Merck Index

EPA CompTox

DTXSID4048773

Created by admin on Fri Dec 15 16:24:21 UTC 2023 , Edited by admin on Fri Dec 15 16:24:21 UTC 2023

PRIMARY

NCI_THESAURUS

C75985

Created by admin on Fri Dec 15 16:24:21 UTC 2023 , Edited by admin on Fri Dec 15 16:24:21 UTC 2023

PRIMARY

FDA UNII

6734037O3L

Created by admin on Fri Dec 15 16:24:21 UTC 2023 , Edited by admin on Fri Dec 15 16:24:21 UTC 2023

PRIMARY

MESH

C501413

Created by admin on Fri Dec 15 16:24:21 UTC 2023 , Edited by admin on Fri Dec 15 16:24:21 UTC 2023

PRIMARY

WIKIPEDIA

TESAGLITAZAR

Created by admin on Fri Dec 15 16:24:21 UTC 2023 , Edited by admin on Fri Dec 15 16:24:21 UTC 2023

PRIMARY

CAS

251565-85-2

Created by admin on Fri Dec 15 16:24:21 UTC 2023 , Edited by admin on Fri Dec 15 16:24:21 UTC 2023

PRIMARY

DRUG BANK

DB06536

Created by admin on Fri Dec 15 16:24:21 UTC 2023 , Edited by admin on Fri Dec 15 16:24:21 UTC 2023

PRIMARY

PUBCHEM

208901

Created by admin on Fri Dec 15 16:24:21 UTC 2023 , Edited by admin on Fri Dec 15 16:24:21 UTC 2023

PRIMARY

USAN

QQ-51

Created by admin on Fri Dec 15 16:24:21 UTC 2023 , Edited by admin on Fri Dec 15 16:24:21 UTC 2023

PRIMARY

SMS_ID

100000089231

Created by admin on Fri Dec 15 16:24:21 UTC 2023 , Edited by admin on Fri Dec 15 16:24:21 UTC 2023

PRIMARY

EVMPD

SUB25217

Created by admin on Fri Dec 15 16:24:21 UTC 2023 , Edited by admin on Fri Dec 15 16:24:21 UTC 2023

PRIMARY

ChEMBL

CHEMBL282686

Created by admin on Fri Dec 15 16:24:21 UTC 2023 , Edited by admin on Fri Dec 15 16:24:21 UTC 2023

PRIMARY

Related Record Type Details


					6734037O3L

EXCRETED UNCHANGED

Qualification:

URINE

Amount:


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					2PDN1S3FVX

PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA

TARGET -> AGONIST

Comments:

Tesaglitazar is a novel dual-acting peroxisome proliferator-activated receptor alpha and gamma agonist.


					AL17N8ZSWL

PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA

TARGET -> AGONIST

Comments:

Tesaglitazar is a novel dual-acting peroxisome proliferator-activated receptor alpha and gamma agonist.

Related Record Type Details


					9D2588L22Y

(2S,3S,4S,5R,6S)-6-((2S)-2-ETHOXY-3-(4-(2-(4-METHYLSULFONYLOXYPHENYL)ETHOXY)PHENYL)PROPANOYL)OXY-3,4,5-TRIHYDROXY-TETRAHYDROPYRAN-2-CARBOXYLIC ACID

METABOLITE -> PARENT

Related Record Type Details


					6734037O3L

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC

Volume of Distribution	PHARMACOKINETIC				INTRAVENOUS ADMINISTRATION AT STEADY-STATE

Tmax	PHARMACOKINETIC				ORAL ADMINISTRATION