LOPERAMIDE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C29H33ClN2O2
Molecular Weight	477.038
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of LOPERAMIDE

Structure Search

SMILES

CN(C)C(=O)C(CCN1CCC(O)(CC1)C2=CC=C(Cl)C=C2)(C3=CC=CC=C3)C4=CC=CC=C4

InChI

InChIKey=RDOIQAHITMMDAJ-UHFFFAOYSA-N

InChI=1S/C29H33ClN2O2/c1-31(2)27(33)29(24-9-5-3-6-10-24,25-11-7-4-8-12-25)19-22-32-20-17-28(34,18-21-32)23-13-15-26(30)16-14-23/h3-16,34H,17-22H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C29H33ClN2O2
Molecular Weight	477.038
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:42:34 UTC 2023` Edited by `admin` on `Fri Dec 15 15:42:34 UTC 2023`
Record UNII	6X9OC3H4II
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

LOPERAMIDE

Official Name

English

LOPERAMIDE [VANDF]

Common Name

English

1-PIPERIDINEBUTANAMIDE, 4-(4-CHLOROPHENYL)-4-HYDROXY-N,N-DIMETHYL-.ALPHA.,.ALPHA.-DIPHENYL-

Systematic Name

English

Loperamide [WHO-DD]

Common Name

English

4-(P-CHLOROPHENYL)-4-HYDROXY-N,N-DIMETHYL-.ALPHA.,.ALPHA.-DIPHENYL-1-PIPERIDINEBUTYRAMIDE

Common Name

English

loperamide [INN]

Common Name

English

LOPERAMIDE [MI]

Common Name

English

LOPERAMIDE [JAN]

Common Name

English

LOPERAMIDE OXIDE MONOHYDRATE IMPURITY A [EP IMPURITY]

Common Name

English

Classification Tree Code System Code

WHO-VATC

QA07DA03

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

WHO-ATC

A07DA53

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

WHO-ATC

A07DA03

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

NCI_THESAURUS

C1506

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

NDF-RT

N0000175690

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

NCI_THESAURUS

C266

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

NDF-RT

N0000000174

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

LIVERTOX

NBK547935

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

WHO-VATC

QA07DA53

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

Code System Code Type Description

FDA UNII

6X9OC3H4II

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

PRIMARY

CAS

53179-11-6

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

PRIMARY

INN

3098

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

PRIMARY

EPA CompTox

DTXSID6045165

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

PRIMARY

ChEMBL

CHEMBL841

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

PRIMARY

PUBCHEM

3955

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

PRIMARY

MESH

D008139

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

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WIKIPEDIA

LOPERAMIDE

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

PRIMARY

HSDB

8344

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

PRIMARY

NCI_THESAURUS

C618

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

PRIMARY

LACTMED

Loperamide

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

PRIMARY

EVMPD

SUB08572MIG

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

PRIMARY

SMS_ID

100000082007

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

PRIMARY

IUPHAR

7215

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

PRIMARY

CHEBI

6532

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

PRIMARY

DRUG CENTRAL

1599

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

PRIMARY

DRUG BANK

DB00836

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

PRIMARY

RXCUI

6468

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

PRIMARY

RxNorm

MERCK INDEX

m6898

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

PRIMARY

Merck Index

ECHA (EC/EINECS)

258-416-5

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

PRIMARY

DAILYMED

6X9OC3H4II

Created by admin on Fri Dec 15 15:42:34 UTC 2023 , Edited by admin on Fri Dec 15 15:42:34 UTC 2023

PRIMARY

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Amount:


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Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:

Related Record Type Details


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ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC