FAMITINIB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C23H27FN4O2
Molecular Weight	410.4845
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure of FAMITINIB

Structure Search

SMILES

CCN(CC)CCN1CCC2=C(C(C)=C(N2)\C=C3/C(=O)NC4=C3C=C(F)C=C4)C1=O

InChI

InChIKey=GKEYKDOLBLYGRB-LGMDPLHJSA-N

InChI=1S/C23H27FN4O2/c1-4-27(5-2)10-11-28-9-8-19-21(23(28)30)14(3)20(25-19)13-17-16-12-15(24)6-7-18(16)26-22(17)29/h6-7,12-13,25H,4-5,8-11H2,1-3H3,(H,26,29)/b17-13-

HIDE SMILES / InChI

Molecular Formula	C23H27FN4O2
Molecular Weight	410.4845
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 05:40:43 UTC 2023` Edited by `admin` on `Sat Dec 16 05:40:43 UTC 2023`
Record UNII	768FW21J3L
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

FAMITINIB

Official Name

English

(Z)-5-(2-(DIETHYLAMINO)ETHYL)-2-((5-FLUORO-2-OXOINDOLIN-3-YLIDENE)METHYL)-3-METHYL-6,7-DIHYDRO-1H-PYRROLO(3,2-C)PYRIDIN-4(5H)-ONE

Systematic Name

English

Famitinib [WHO-DD]

Common Name

English

4H-PYRROLO(3,2-C)PYRIDIN-4-ONE, 5-(2-(DIETHYLAMINO)ETHYL)-2-((Z)-(5-FLUORO-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)METHYL)-1,5,6,7-TETRAHYDRO-3-METHYL-

Systematic Name

English

4H-PYRROLO(3,2-C)PYRIDIN-4-ONE, 5-(2-(DIETHYLAMINO)ETHYL)-2-((5-FLUORO-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)METHYL)-1,5,6,7-TETRAHYDRO-3-METHYL-

Systematic Name

English

famitinib [INN]

Common Name

English

SHR1020

Code

English

SHR-1020

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C129825

Created by admin on Sat Dec 16 05:40:43 UTC 2023 , Edited by admin on Sat Dec 16 05:40:43 UTC 2023

NCI_THESAURUS

C1967

Created by admin on Sat Dec 16 05:40:43 UTC 2023 , Edited by admin on Sat Dec 16 05:40:43 UTC 2023

Code System Code Type Description

NCI_THESAURUS

C97512

Created by admin on Sat Dec 16 05:40:43 UTC 2023 , Edited by admin on Sat Dec 16 05:40:43 UTC 2023

PRIMARY

CAS

1044040-56-3

Created by admin on Sat Dec 16 05:40:43 UTC 2023 , Edited by admin on Sat Dec 16 05:40:43 UTC 2023

PRIMARY

SMS_ID

100000169823

Created by admin on Sat Dec 16 05:40:43 UTC 2023 , Edited by admin on Sat Dec 16 05:40:43 UTC 2023

PRIMARY

ChEMBL

CHEMBL3545026

Created by admin on Sat Dec 16 05:40:43 UTC 2023 , Edited by admin on Sat Dec 16 05:40:43 UTC 2023

PRIMARY

INN

11724

Created by admin on Sat Dec 16 05:40:43 UTC 2023 , Edited by admin on Sat Dec 16 05:40:43 UTC 2023

PRIMARY

EVMPD

SUB183614

Created by admin on Sat Dec 16 05:40:43 UTC 2023 , Edited by admin on Sat Dec 16 05:40:43 UTC 2023

PRIMARY

PUBCHEM

16662431

Created by admin on Sat Dec 16 05:40:43 UTC 2023 , Edited by admin on Sat Dec 16 05:40:43 UTC 2023

PRIMARY

CAS

945380-27-8

Created by admin on Sat Dec 16 05:40:43 UTC 2023 , Edited by admin on Sat Dec 16 05:40:43 UTC 2023

NON-SPECIFIC STEREOCHEMISTRY

FDA UNII

768FW21J3L

Created by admin on Sat Dec 16 05:40:43 UTC 2023 , Edited by admin on Sat Dec 16 05:40:43 UTC 2023

PRIMARY

DRUG BANK

DB11741

Created by admin on Sat Dec 16 05:40:43 UTC 2023 , Edited by admin on Sat Dec 16 05:40:43 UTC 2023

PRIMARY

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Interaction Type:

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SALT/SOLVATE -> PARENT


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VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2

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					768FW21J3L

FAMITINIB

ACTIVE MOIETY