UPANOVIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 12:12:23 GMT 2025` Edited by `admin` on `Wed Apr 02 12:12:23 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Type	COMPLETE
Record UNII	8E88WSA6X3
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

UPANOVIMAB

Official Name

English

SCTA-01

Preferred Name

English

SCTA01

Code

English

upanovimab [INN]

Common Name

English

IMMUNOGLOBULIN G1, ANTI-(SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 SPIKE GLYCOPROTEIN) (HUMAN-MUS MUSCULUS MONOCLONAL SCTA01 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL SCTA01 .KAPPA.-CHAIN, DIMER

Common Name

English

SCTA 01 [WHO-DD]

Common Name

English

Code System Code Type Description

FDA UNII

8E88WSA6X3

Created by admin on Wed Apr 02 12:12:23 GMT 2025 , Edited by admin on Wed Apr 02 12:12:23 GMT 2025

PRIMARY

INN

11966

Created by admin on Wed Apr 02 12:12:23 GMT 2025 , Edited by admin on Wed Apr 02 12:12:23 GMT 2025

PRIMARY

CAS

2500633-46-3

Created by admin on Wed Apr 02 12:12:23 GMT 2025 , Edited by admin on Wed Apr 02 12:12:23 GMT 2025

PRIMARY

SMS_ID

300000026071

Created by admin on Wed Apr 02 12:12:23 GMT 2025 , Edited by admin on Wed Apr 02 12:12:23 GMT 2025

PRIMARY

NCI_THESAURUS

C175228

Created by admin on Wed Apr 02 12:12:23 GMT 2025 , Edited by admin on Wed Apr 02 12:12:23 GMT 2025

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_148	2_204
2_224	4_218
2_265	2_325
1_148	1_204
2_371	2_429
3_23	3_92
3_138	3_198
4_23	4_92
4_138	4_198
1_224	3_218
1_230	2_230
1_233	2_233
1_265	1_325
1_371	1_429

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_301
N	2_301

Related Record Type Details


					B6L4N5Z4GH

SARS-COV2

TARGET ORGANISM->INHIBITOR

Interaction Type:

IN-VITRO

Amount:


					0EO1SV3LKY

SPIKE-1 PROTEIN SARS-COV-2

TARGET -> INHIBITOR

Interaction Type:

IN-VITRO

Amount:

Related Record Type Details


					8E88WSA6X3

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]			Amount:	PIDOLIC ACID	SZB83O1W42
AMINO ACID REMOVAL	[1_451] [2_451]	C-TERMINUS			LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL