U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Wed Apr 02 08:54:32 GMT 2025
Edited
by admin
on Wed Apr 02 08:54:32 GMT 2025
Protein Type BISPECIFIC ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
8PMF8YQX2T
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DULIGOTUZUMAB
INN   USAN  
INN   USAN  
Official Name English
DULIGOTUMAB
WHO-DD  
Preferred Name English
RG7597
Code English
DULIGOTUZUMAB [USAN]
Common Name English
duligotuzumab [INN]
Common Name English
IMMUNOGLOBULIN G1, ANTI-(HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR/EPIDERMAL GROWTH FACTOR RECEPTOR 3) (HUMAN MONOCLONAL MEHD7945A HEAVY CHAIN), DISULFIDE WITH HUMAN MONOCLONAL MEHD7945A LIGHT CHAIN, DIMER
Common Name English
BISPECIFIC HUMANIZED IGG1 MONOCLONAL ANTIBODY TO EPIDERMAL GROWTH FACTOR RECEPTOR AND HER3
Common Name English
MEHD7945A
Code English
Duligotuzumab [WHO-DD]
Common Name English
MEHD-7945A
Code English
RG-7597
Code English
Classification Tree Code System Code
NCI_THESAURUS C20401
Created by admin on Wed Apr 02 08:54:32 GMT 2025 , Edited by admin on Wed Apr 02 08:54:32 GMT 2025
Code System Code Type Description
FDA UNII
8PMF8YQX2T
Created by admin on Wed Apr 02 08:54:32 GMT 2025 , Edited by admin on Wed Apr 02 08:54:32 GMT 2025
PRIMARY
ChEMBL
CHEMBL2109405
Created by admin on Wed Apr 02 08:54:32 GMT 2025 , Edited by admin on Wed Apr 02 08:54:32 GMT 2025
PRIMARY
INN
9646
Created by admin on Wed Apr 02 08:54:32 GMT 2025 , Edited by admin on Wed Apr 02 08:54:32 GMT 2025
PRIMARY
WIKIPEDIA
Duligotuzumab
Created by admin on Wed Apr 02 08:54:32 GMT 2025 , Edited by admin on Wed Apr 02 08:54:32 GMT 2025
PRIMARY
SMS_ID
100000175729
Created by admin on Wed Apr 02 08:54:32 GMT 2025 , Edited by admin on Wed Apr 02 08:54:32 GMT 2025
PRIMARY
ChEMBL
CHEMBL3137345
Created by admin on Wed Apr 02 08:54:32 GMT 2025 , Edited by admin on Wed Apr 02 08:54:32 GMT 2025
PRIMARY
ChEMBL
CHEMBL2109403
Created by admin on Wed Apr 02 08:54:32 GMT 2025 , Edited by admin on Wed Apr 02 08:54:32 GMT 2025
PRIMARY
CAS
1361184-57-7
Created by admin on Wed Apr 02 08:54:32 GMT 2025 , Edited by admin on Wed Apr 02 08:54:32 GMT 2025
NO STRUCTURE GIVEN
DRUG BANK
DB12142
Created by admin on Wed Apr 02 08:54:32 GMT 2025 , Edited by admin on Wed Apr 02 08:54:32 GMT 2025
PRIMARY
USAN
ZZ-138
Created by admin on Wed Apr 02 08:54:32 GMT 2025 , Edited by admin on Wed Apr 02 08:54:32 GMT 2025
PRIMARY
CAS
1314238-96-4
Created by admin on Wed Apr 02 08:54:32 GMT 2025 , Edited by admin on Wed Apr 02 08:54:32 GMT 2025
PRIMARY
NCI_THESAURUS
C116628
Created by admin on Wed Apr 02 08:54:32 GMT 2025 , Edited by admin on Wed Apr 02 08:54:32 GMT 2025
PRIMARY
From To
1_22 1_96
1_148 1_204
1_265 1_325
1_371 1_429
2_22 2_96
2_148 2_204
2_265 2_325
2_371 2_429
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
1_224 3_214
2_224 4_214
1_230 2_230
1_233 2_233
Glycosylation Link Type Site
N 1_301
N 2_301
Related Record Type Details
EPIDERMAL GROWTH FACTOR RECEPTOR
TARGET -> INHIBITOR
RECEPTOR TYROSINE-PROTEIN KINASE ERBB-3
TARGET -> INHIBITOR
Related Record Type Details
DULIGOTUZUMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
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