NIVATROTAMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 06:52:37 GMT 2025` Edited by `admin` on `Wed Apr 02 06:52:37 GMT 2025`
Protein Type	FUSION PROTEINS
Protein Sub Type
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	8RV18E4A94
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

HU3F8-BSAB

Preferred Name

English

NIVATROTAMAB

Official Name

English

IMMUNOGLOBULIN, ANTI-(GANGLIOSIDE GD2) (HUMAN-MUS MUSCULUS MONOCLONAL 3F8 .KAPPA.-CHAIN) FUSION PROTEIN WITH PEPTIDE LINKER (TS(GGGGS)3) FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN CD3 ANTIGEN .EPSILON.-CHAIN) (HUMAN-MUS MUSCULUS MONOCLONAL OKT3 SINGL

Common Name

English

NIVATROTAMAB [USAN]

Common Name

English

HU3F8BSAB

Code

English

nivatrotamab [INN]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

767020

Created by admin on Wed Apr 02 06:52:37 GMT 2025 , Edited by admin on Wed Apr 02 06:52:37 GMT 2025

Code System Code Type Description

NCI_THESAURUS

C158436

Created by admin on Wed Apr 02 06:52:37 GMT 2025 , Edited by admin on Wed Apr 02 06:52:37 GMT 2025

PRIMARY

SMS_ID

300000032318

Created by admin on Wed Apr 02 06:52:37 GMT 2025 , Edited by admin on Wed Apr 02 06:52:37 GMT 2025

PRIMARY

CAS

2278244-14-5

Created by admin on Wed Apr 02 06:52:37 GMT 2025 , Edited by admin on Wed Apr 02 06:52:37 GMT 2025

PRIMARY

FDA UNII

8RV18E4A94

Created by admin on Wed Apr 02 06:52:37 GMT 2025 , Edited by admin on Wed Apr 02 06:52:37 GMT 2025

PRIMARY

INN

11591

Created by admin on Wed Apr 02 06:52:37 GMT 2025 , Edited by admin on Wed Apr 02 06:52:37 GMT 2025

PRIMARY

From	To
4_369	4_427
4_263	4_323
4_146	4_202
4_22	4_95
3_369	3_427
3_263	3_323
3_231	4_231
3_228	4_228
3_146	3_202
3_22	3_95
2_400	2_464
1_400	1_464
2_211	4_222
1_211	3_222
2_272	2_476
2_250	2_324
2_131	2_191
2_23	2_88
1_272	1_476
1_250	1_324
1_131	1_191
1_23	1_88

Related Record Type Details


					ZLW14X2D30

CD3

TARGET->LIGAND

Amount:


					FUI2V09E1C

DISIALOGANGLIOSIDE GD-2

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					8RV18E4A94

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[3_449] [4_449]	C-TERMINUS			LYSINE	K3Z4F929H6
AMINO_ACID_SUBSTITUTION	[3_1] [4_1]	N-TERMINUS			PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL

Molecular Formula	CHEMICAL