OXYMORPHONE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C17H19NO4
Molecular Weight	301.3371
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of OXYMORPHONE

Structure Search

SMILES

CN1CC[C@@]23[C@H]4OC5=C2C(C[C@@H]1[C@]3(O)CCC4=O)=CC=C5O

InChI

InChIKey=UQCNKQCJZOAFTQ-ISWURRPUSA-N

InChI=1S/C17H19NO4/c1-18-7-6-16-13-9-2-3-10(19)14(13)22-15(16)11(20)4-5-17(16,21)12(18)8-9/h2-3,12,15,19,21H,4-8H2,1H3/t12-,15+,16+,17-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C17H19NO4
Molecular Weight	301.3371
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:16:42 UTC 2023` Edited by `admin` on `Fri Dec 15 16:16:42 UTC 2023`
Record UNII	9VXA968E0C
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

OXYMORPHONE

Official Name

English

OXYMORPHONE CII [USP-RS]

Common Name

English

OXYCODONE HYDROCHLORIDE IMPURITY A [EP IMPURITY]

Common Name

English

4,5.ALPHA.-EPOXY-3,14-DIHYDROXY-17-METHYLMORPHINAN-6-ONE

Systematic Name

English

NIH 10323

Code

English

OXYMORPHONE [VANDF]

Common Name

English

OXYCODONE HYDROCHLORIDE IMPURITY, OXYMORPHONE- [USP IMPURITY]

Common Name

English

DIHYDROXYMORPHINONE

Common Name

English

IDS-NO-003

Code

English

MORPHINAN-6-ONE, 4,5-EPOXY-3,14-DIHYDROXY-17-METHYL-

Systematic Name

English

14-HYDROXYDIHYDROMORPHINONE

Common Name

English

oxymorphone [INN]

Common Name

English

OXYMORPHONE CII

Common Name

English

7,8-DIHYDRO-14-HYDROXYMORPHINONE

Common Name

English

Oxymorphone [WHO-DD]

Common Name

English

OXYMORPHONE [MI]

Common Name

English

NSC-19045

Code

English

Classification Tree Code System Code

NDF-RT

N0000175690

Created by admin on Fri Dec 15 16:16:42 UTC 2023 , Edited by admin on Fri Dec 15 16:16:42 UTC 2023

NCI_THESAURUS

C67413

Created by admin on Fri Dec 15 16:16:42 UTC 2023 , Edited by admin on Fri Dec 15 16:16:42 UTC 2023

LIVERTOX

NBK548775

Created by admin on Fri Dec 15 16:16:42 UTC 2023 , Edited by admin on Fri Dec 15 16:16:42 UTC 2023

NDF-RT

N0000175684

Created by admin on Fri Dec 15 16:16:42 UTC 2023 , Edited by admin on Fri Dec 15 16:16:42 UTC 2023

NCI_THESAURUS

C1506

Created by admin on Fri Dec 15 16:16:42 UTC 2023 , Edited by admin on Fri Dec 15 16:16:42 UTC 2023

FDA ORPHAN DRUG

6185

Created by admin on Fri Dec 15 16:16:42 UTC 2023 , Edited by admin on Fri Dec 15 16:16:42 UTC 2023

DEA NO.

9652

Created by admin on Fri Dec 15 16:16:42 UTC 2023 , Edited by admin on Fri Dec 15 16:16:42 UTC 2023

Code System Code Type Description

HSDB

8060

Created by admin on Fri Dec 15 16:16:42 UTC 2023 , Edited by admin on Fri Dec 15 16:16:42 UTC 2023

PRIMARY

RXCUI

7814

Created by admin on Fri Dec 15 16:16:42 UTC 2023 , Edited by admin on Fri Dec 15 16:16:42 UTC 2023

PRIMARY

RxNorm

NCI_THESAURUS

C29314

Created by admin on Fri Dec 15 16:16:42 UTC 2023 , Edited by admin on Fri Dec 15 16:16:42 UTC 2023

PRIMARY

PUBCHEM

5284604

Created by admin on Fri Dec 15 16:16:42 UTC 2023 , Edited by admin on Fri Dec 15 16:16:42 UTC 2023

PRIMARY

NSC

19045

Created by admin on Fri Dec 15 16:16:42 UTC 2023 , Edited by admin on Fri Dec 15 16:16:42 UTC 2023

PRIMARY

EVMPD

SUB09569MIG

Created by admin on Fri Dec 15 16:16:42 UTC 2023 , Edited by admin on Fri Dec 15 16:16:42 UTC 2023

PRIMARY

DAILYMED

9VXA968E0C

Created by admin on Fri Dec 15 16:16:42 UTC 2023 , Edited by admin on Fri Dec 15 16:16:42 UTC 2023

PRIMARY

MERCK INDEX

m8338

Created by admin on Fri Dec 15 16:16:42 UTC 2023 , Edited by admin on Fri Dec 15 16:16:42 UTC 2023

PRIMARY

Merck Index

WIKIPEDIA

OXYMORPHONE

Created by admin on Fri Dec 15 16:16:42 UTC 2023 , Edited by admin on Fri Dec 15 16:16:42 UTC 2023

PRIMARY

DRUG BANK

DB01192

Created by admin on Fri Dec 15 16:16:42 UTC 2023 , Edited by admin on Fri Dec 15 16:16:42 UTC 2023

PRIMARY

ECHA (EC/EINECS)

200-959-7

Created by admin on Fri Dec 15 16:16:42 UTC 2023 , Edited by admin on Fri Dec 15 16:16:42 UTC 2023

PRIMARY

ChEMBL

CHEMBL963

Created by admin on Fri Dec 15 16:16:42 UTC 2023 , Edited by admin on Fri Dec 15 16:16:42 UTC 2023

PRIMARY

EPA CompTox

DTXSID5023409

Created by admin on Fri Dec 15 16:16:42 UTC 2023 , Edited by admin on Fri Dec 15 16:16:42 UTC 2023

PRIMARY

FDA UNII

9VXA968E0C

Created by admin on Fri Dec 15 16:16:42 UTC 2023 , Edited by admin on Fri Dec 15 16:16:42 UTC 2023

PRIMARY

DRUG CENTRAL

2034

Created by admin on Fri Dec 15 16:16:42 UTC 2023 , Edited by admin on Fri Dec 15 16:16:42 UTC 2023

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LACTMED

Oxymorphone

Created by admin on Fri Dec 15 16:16:42 UTC 2023 , Edited by admin on Fri Dec 15 16:16:42 UTC 2023

PRIMARY

SMS_ID

100000083286

Created by admin on Fri Dec 15 16:16:42 UTC 2023 , Edited by admin on Fri Dec 15 16:16:42 UTC 2023

PRIMARY

INN

937

Created by admin on Fri Dec 15 16:16:42 UTC 2023 , Edited by admin on Fri Dec 15 16:16:42 UTC 2023

PRIMARY

MESH

D010111

Created by admin on Fri Dec 15 16:16:42 UTC 2023 , Edited by admin on Fri Dec 15 16:16:42 UTC 2023

PRIMARY

RS_ITEM_NUM

1488000

Created by admin on Fri Dec 15 16:16:42 UTC 2023 , Edited by admin on Fri Dec 15 16:16:42 UTC 2023

PRIMARY

IUPHAR

7094

Created by admin on Fri Dec 15 16:16:42 UTC 2023 , Edited by admin on Fri Dec 15 16:16:42 UTC 2023

PRIMARY

CAS

76-41-5

Created by admin on Fri Dec 15 16:16:42 UTC 2023 , Edited by admin on Fri Dec 15 16:16:42 UTC 2023

PRIMARY

Related Record Type Details


					5Y2EI94NBC

OXYMORPHONE HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Comments:

APPROXIMATE PURE ANHYDROUS DRUG CONTENT (IN PERCENT)

Amount:


					KM542GS55Z

OXYMORPHONE HYDROBROMIDE

SALT/SOLVATE -> PARENT

Amount:


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					CV52YZ5G1X

OXYMORPHONE HYDROCHLORIDE MONOHYDRATE

SALT/SOLVATE -> PARENT

Comments:

APPROXIMATE PURE ANHYDROUS DRUG CONTENT (IN PERCENT)

Amount:


					SYR9B86WW7

OXYMORPHONE HYDRIODIDE

SALT/SOLVATE -> PARENT

Amount:

Related Record Type Details


					1O00P9X5C1

METABOLITE -> PARENT

Comments:

6-OH-oxymorphone has been shown in animal studies to have analgesic bioactivity

Interaction Type:

MAJOR

Qualification:

PLASMA; URINE


					CS1J30867C

OXYMORPHONE 3-GLUCURONIDE

METABOLITE -> PARENT

Interaction Type:

MAJOR

Qualification:

PLASMA


					CD35PMG570

OXYCODONE

PARENT -> METABOLITE ACTIVE

Comments:

Highly variable 40 fold higher potency than Oxycodone

Interaction Type:

MINOR

Qualification:

PLASMA; URINE

Amount:


					67P6D5Q6YK

6.BETA.-OXYMORPHOL

METABOLITE -> PARENT

Comments:

6-OH-oxymorphone has been shown in animal studies to have analgesic bioactivity.

Interaction Type:

MAJOR

Qualification:

URINE

Related Record Type Details


					C1ENJ2TE6C

OXYCODONE HYDROCHLORIDE

PARENT -> IMPURITY

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:

Related Record Type Details


					9VXA968E0C

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC				Elimination PHARMACOKINETIC Elimination PHARMACOKINETIC

Volume of Distribution	PHARMACOKINETIC