Devextinetug

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 01:27:11 GMT 2025` Edited by `admin` on `Wed Apr 02 01:27:11 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG2
Sequence Origin	MOUSE CHIMERIC
Sequence Type	COMPLETE
Record UNII	BT3RCH0595
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Devextinetug

Official Name

English

IXT-m200

Preferred Name

English

Immunoglobulin G2, anti-((+)-methamphetamine) (human-Mus musculus monoclonal IXT-m200 ?2-chain), disulfide with human-Mus musculus monoclonal IXT-m200 ?-chain, dimer

Common Name

English

IXTM-200

Code

English

DEVEXTINETUG [USAN]

Common Name

English

ch-mAb7F9

Code

English

Immunoglobulin G2-kappa, anti-[(+)-metamphetamine)], chimeric monoclonal antibody; gamma2 heavy chain chimeric (1-443) [VH (Mus musculus IGHV1S135*01 (87.6%) -(IGHD) -IGHJ2*01 (92.9%), CDR-IMGT [8.8.10] (26-33.51-58.97-106)) (1-117) -Homo sapiens IGHG2*0

Common Name

English

devextinetug [INN]

Common Name

English

IXTM200

Code

English

Code System Code Type Description

SMS_ID

300000046880

Created by admin on Wed Apr 02 01:27:11 GMT 2025 , Edited by admin on Wed Apr 02 01:27:11 GMT 2025

PRIMARY

FDA UNII

BT3RCH0595

Created by admin on Wed Apr 02 01:27:11 GMT 2025 , Edited by admin on Wed Apr 02 01:27:11 GMT 2025

PRIMARY

USAN

LM-159

Created by admin on Wed Apr 02 01:27:11 GMT 2025 , Edited by admin on Wed Apr 02 01:27:11 GMT 2025

PRIMARY

INN

12180

Created by admin on Wed Apr 02 01:27:11 GMT 2025 , Edited by admin on Wed Apr 02 01:27:11 GMT 2025

PRIMARY

CAS

2609642-90-0

Created by admin on Wed Apr 02 01:27:11 GMT 2025 , Edited by admin on Wed Apr 02 01:27:11 GMT 2025

PRIMARY

NCI_THESAURUS

C190425

Created by admin on Wed Apr 02 01:27:11 GMT 2025 , Edited by admin on Wed Apr 02 01:27:11 GMT 2025

PRIMARY

From	To
1_22	1_96
1_363	1_421
2_22	2_96
2_131	4_215
2_144	2_200
1_131	3_215
2_257	2_317
2_363	2_421
3_23	3_89
3_135	3_195
1_144	1_200
4_23	4_89
4_135	4_195
1_219	2_219
1_220	2_220
1_223	2_223
1_226	2_226
1_257	1_317

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_293
N	2_293

Related Record Type Details


					44RAL3456C

METHAMPHETAMINE

TARGET->LIGAND

Amount:

Related Record Type Details


					BT3RCH0595

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_443] [2_443]	C-TERMINUS			LYSINE	K3Z4F929H6
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]	N-TERMINUS			PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL