SILMITASERTIB

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C19H12ClN3O2
Molecular Weight	349.77
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of SILMITASERTIB

Structure Search

SMILES

OC(=O)C1=CC2=C(C=C1)C3=C(C=CN=C3)C(NC4=CC(Cl)=CC=C4)=N2

InChI

InChIKey=MUOKSQABCJCOPU-UHFFFAOYSA-N

InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25)

HIDE SMILES / InChI

Molecular Formula	C19H12ClN3O2
Molecular Weight	349.77
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:41:59 UTC 2023` Edited by `admin` on `Fri Dec 15 18:41:59 UTC 2023`
Record UNII	C6RWP0N0L2
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

SILMITASERTIB

Official Name

English

BENZO(C)-2,6-NAPHTHYRIDINE-8-CARBOXYLIC ACID, 5-((3-CHLOROPHENYL)AMINO)-

Common Name

English

silmitasertib [INN]

Common Name

English

Silmitasertib [WHO-DD]

Common Name

English

CX4945

Code

English

CX 4945

Code

English

5-((3-CHLOROPHENYL)AMINO)BENZO(C)(2,6)NAPHTHYRIDINE-8-CARBOXYLIC ACID

Systematic Name

English

CX-4945 FREE ACID

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1404

Created by admin on Fri Dec 15 18:41:59 UTC 2023 , Edited by admin on Fri Dec 15 18:41:59 UTC 2023

FDA ORPHAN DRUG

548516

Created by admin on Fri Dec 15 18:41:59 UTC 2023 , Edited by admin on Fri Dec 15 18:41:59 UTC 2023

FDA ORPHAN DRUG

856821

Created by admin on Fri Dec 15 18:41:59 UTC 2023 , Edited by admin on Fri Dec 15 18:41:59 UTC 2023

FDA ORPHAN DRUG

851021

Created by admin on Fri Dec 15 18:41:59 UTC 2023 , Edited by admin on Fri Dec 15 18:41:59 UTC 2023

Code System Code Type Description

NCI_THESAURUS

C129825

Created by admin on Fri Dec 15 18:41:59 UTC 2023 , Edited by admin on Fri Dec 15 18:41:59 UTC 2023

CONCEPT

PUBCHEM

24748573

Created by admin on Fri Dec 15 18:41:59 UTC 2023 , Edited by admin on Fri Dec 15 18:41:59 UTC 2023

PRIMARY

WIKIPEDIA

Silmitasertib

Created by admin on Fri Dec 15 18:41:59 UTC 2023 , Edited by admin on Fri Dec 15 18:41:59 UTC 2023

PRIMARY

SMS_ID

300000021749

Created by admin on Fri Dec 15 18:41:59 UTC 2023 , Edited by admin on Fri Dec 15 18:41:59 UTC 2023

PRIMARY

CAS

1009820-21-6

Created by admin on Fri Dec 15 18:41:59 UTC 2023 , Edited by admin on Fri Dec 15 18:41:59 UTC 2023

PRIMARY

DRUG BANK

DB15408

Created by admin on Fri Dec 15 18:41:59 UTC 2023 , Edited by admin on Fri Dec 15 18:41:59 UTC 2023

PRIMARY

FDA UNII

C6RWP0N0L2

Created by admin on Fri Dec 15 18:41:59 UTC 2023 , Edited by admin on Fri Dec 15 18:41:59 UTC 2023

PRIMARY

EPA CompTox

DTXSID40143602

Created by admin on Fri Dec 15 18:41:59 UTC 2023 , Edited by admin on Fri Dec 15 18:41:59 UTC 2023

PRIMARY

ChEMBL

CHEMBL1230165

Created by admin on Fri Dec 15 18:41:59 UTC 2023 , Edited by admin on Fri Dec 15 18:41:59 UTC 2023

PRIMARY

INN

9213

Created by admin on Fri Dec 15 18:41:59 UTC 2023 , Edited by admin on Fri Dec 15 18:41:59 UTC 2023

PRIMARY

NCI_THESAURUS

C98054

Created by admin on Fri Dec 15 18:41:59 UTC 2023 , Edited by admin on Fri Dec 15 18:41:59 UTC 2023

PRIMARY

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					5NJ22TAB5Y

SERINE/THREONINE-PROTEIN KINASE PIM-1

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CASEIN KINASE II SUBUNIT ALPHA

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					1N1D7O62X2

SERINE/THREONINE-PROTEIN KINASE PIM-2

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					T39UDE9EDQ

CASEIN KINASE II

TARGET -> INHIBITOR

Qualification:

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Amount:


					N1E607PU86

SILMITASERTIB SODIUM

SALT/SOLVATE -> PARENT

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					C6RWP0N0L2

ACTIVE MOIETY