Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Tue Apr 01 18:08:46 GMT 2025
by
admin
on
Tue Apr 01 18:08:46 GMT 2025
|
| Protein Sub Type | |
| Sequence Type | COMPLETE |
| Record UNII |
D8T754TT2I
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Preferred Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
P35354
Created by
admin on Tue Apr 01 18:08:46 GMT 2025 , Edited by admin on Tue Apr 01 18:08:46 GMT 2025
|
PRIMARY | |||
|
100000177620
Created by
admin on Tue Apr 01 18:08:46 GMT 2025 , Edited by admin on Tue Apr 01 18:08:46 GMT 2025
|
PRIMARY | |||
|
D8T754TT2I
Created by
admin on Tue Apr 01 18:08:46 GMT 2025 , Edited by admin on Tue Apr 01 18:08:46 GMT 2025
|
PRIMARY |
| From | To |
|---|---|
| 1_4 | 1_15 |
| 1_5 | 1_128 |
| 1_9 | 1_25 |
| 1_27 | 1_37 |
| 1_538 | 1_544 |
| Glycosylation Type | HUMAN |
| Glycosylation Link Type | Site |
|---|---|
| N | 1_36 |
| N | 1_113 |
| N | 1_379 |
| N | 1_563 |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
INHIBITOR -> TARGET |
|
||
|
INHIBITOR -> TARGET |
|
||
|
INHIBITOR -> TARGET |
IC50
|
||
|
|
INHIBITOR -> TARGET |
Metabolite I, formed by hydroxylation of the methyl group, and its glucuronide conjugates accounted for 50 to 60 per cent of radioactivity in urine (approximately 35 per cent of dose). This metabolite possesses pharmacologic activity equal to one-fifth that of meclofenamic acid in an in vim system which measures inhibition of bovine seminal vesicle cyclo~xygenase.
|
||
|
|
INHIBITOR -> TARGET |
|
||
|
INHIBITOR -> TARGET |
|
||
|
INHIBITOR -> METABOLIC ENZYME | |||
|
INHIBITOR -> TARGET |
|
||
|
|
INHIBITOR -> TARGET |
|
||
|
|
INHIBITOR -> TARGET |
|
||
|
INHIBITOR -> TARGET |
IC50
|
||
|
|
INHIBITOR -> TARGET |
Selective used in small animals (dogs)
|
||
|
INHIBITOR -> TARGET |
|
||
|
|
INHIBITOR->OFF-TARGET |
IC50
|
||
|
INHIBITOR -> TARGET |
|
||
|
INHIBITOR OF EXPRESSION->TARGET |
|
||
|
|
RADIOLIGAND->TARGET |
|
||
|
INHIBITOR -> TARGET |
IC50
|
||
|
INHIBITOR OF EXPRESSION->TARGET |
|
||
|
INHIBITOR -> TARGET |
|
||
|
INHIBITOR -> TARGET |
|
||
|
|
INHIBITOR -> TARGET | |||
|
INHIBITOR -> TARGET |
IC50
|
||
|
INHIBITOR -> TARGET |
|
||
|
INHIBITOR -> TARGET |
|
||
|
|
INHIBITOR -> TARGET |
|
||
|
|
INHIBITOR -> TARGET | |||
|
INHIBITOR -> TARGET |
|
||
|
INHIBITOR -> TARGET |
IC50
|
||
|
INHIBITOR -> TARGET |
|
||
|
INHIBITOR -> TARGET |
|
||
|
INHIBITOR -> TARGET |
|
||
|
INHIBITOR -> TARGET |
SELECTIVE
|
||
|
INHIBITOR -> TARGET | |||
|
INHIBITOR -> TARGET |
|
||
|
|
INHIBITOR -> TARGET |
|
||
|
INHIBITOR -> TARGET |
|
||
|
INHIBITOR -> TARGET |
|
||
|
INHIBITOR -> TARGET |
|
||
|
|
INHIBITOR -> TARGET |
|
||
|
INHIBITOR -> TARGET |
IC50
|
||
|
|
INHIBITOR -> TARGET |
|
||
|
|
INHIBITOR -> TARGET |
|
||
|
|
INHIBITOR -> TARGET |
![Structure of N-[2-(Cyclohexyloxy)-4-nitrophenyl]methanesulfonamide](/img/677f3c4c-36ca-4775-b412-8479683f9935.svg "Structure of N-[2-(Cyclohexyloxy)-4-nitrophenyl]methanesulfonamide")
Structural Modifications
| Modification Type | Location Site | Location Type | Residue Modified | Extent | Fragment Name | Fragment Approval |
|---|---|---|---|---|---|---|
| AMINO ACID SUBSTITUTION | [1_509] | S-NITROSOCYSTEINE | 926P2322P4 |
| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| MOL_WEIGHT | CHEMICAL |
|
||||
| Molecular Formula | CHEMICAL |
|