EMILIMOGENE SIGULACTIBAC

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Wed Apr 02 11:06:51 GMT 2025` Edited by `admin` on `Wed Apr 02 11:06:51 GMT 2025`
Source Materials Class	ORGANISM
Source Materials Type	BACTERIUM
Source Materials State	LIVE GENETICALLY MODIFIED
Organism Family	Lactobacillaceae
Organism Genus	Lactobacillus
Organism Species	reuteri
Infraspecific Type	STRAIN
Infraspecific Name	R2LC
Part	whole
Record UNII	FBZ2DKU32N
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

EMILIMOGENE SIGULACTIBAC

Official Name

English

ILP-100

Preferred Name

English

emilimogene sigulactibac [INN]

Common Name

English

IPL100

Common Name

English

RECOMBINANT LIVE LIMOSILACTOBACILLUS REUTERI BACTERIA (PREVIOUSLY KNOWN AS LACTOBACILLUS REUTERI), STRAIN R2LC, TRANSFORMED WITH A PLASMID EXPRESSING A CODON-OPTIMISED HUMAN C-X-C MOTIF CHEMOKINE LIGAND 12 ISOFORM ALPHA (CXCL12-1.ALPHA.; ALSO KNOWN AS ST

Common Name

English

Code System Code Type Description

FDA UNII

FBZ2DKU32N

Created by admin on Wed Apr 02 11:06:51 GMT 2025 , Edited by admin on Wed Apr 02 11:06:51 GMT 2025

PRIMARY

INN

12097

Created by admin on Wed Apr 02 11:06:51 GMT 2025 , Edited by admin on Wed Apr 02 11:06:51 GMT 2025

PRIMARY

NCI_THESAURUS

C188572

Created by admin on Wed Apr 02 11:06:51 GMT 2025 , Edited by admin on Wed Apr 02 11:06:51 GMT 2025

PRIMARY

SMS_ID

300000042042

Created by admin on Wed Apr 02 11:06:51 GMT 2025 , Edited by admin on Wed Apr 02 11:06:51 GMT 2025

PRIMARY

Related Record Type Details


					7AD3GF5H3H

STROMAL CELL-DERIVED FACTOR 1

EXPRESSED PROTEIN->VECTOR

Amount:


					B5GGG91KI4

C-X-C CHEMOKINE RECEPTOR TYPE 4

TARGET -> AGONIST

Comments:

Dimeric form acts as a partial agonist of CXCR4.

Amount:


					PTH9WCP7HT

LIMOSILACTOBACILLUS REUTERI STRAIN R2LC

PARENT -> DERIVATIVE

Amount:


					9913I24QEE

Limosilactobacillus reuteri

PARENT ORGANISM -> INFRASPECIFIC

Amount:

Related Record Type Details


					FBZ2DKU32N

EMILIMOGENE SIGULACTIBAC

ACTIVE MOIETY

Comments:

immunomodulator

Amount:

Structural Modifications

Modification Type	Fragment Name	Fragment Approval
VECTOR EXPRESSED PROTEIN	EMILIMOGENE SIGULACTIBAC EXPRESSED STROMAL CELL-DERIVED FACTOR 1 ALPHA PREPROTEIN	JVL4Q62KAV
INSERTED GENE EXPRESSION VECTOR	EMILIMOGENE SIGULACTIBAC TRANSGENE PLASMID	BJH8KD4UJX
VECTOR EXPRESSED PROTEIN	STROMAL CELL-DERIVED FACTOR 1-ALPHA	CPN2JYW64D