U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C22H17ClN2
Molecular Weight 344.837
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CLOTRIMAZOLE

SMILES

ClC1=CC=CC=C1C(N2C=CN=C2)(C3=CC=CC=C3)C4=CC=CC=C4

InChI

InChIKey=VNFPBHJOKIVQEB-UHFFFAOYSA-N
InChI=1S/C22H17ClN2/c23-21-14-8-7-13-20(21)22(25-16-15-24-17-25,18-9-3-1-4-10-18)19-11-5-2-6-12-19/h1-17H

HIDE SMILES / InChI

Molecular Formula C22H17ClN2
Molecular Weight 344.837
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including http://www.accessdata.fda.gov/drugsatfda_docs/label/2010/018052Orig1s032lbl.pdf

Clotrimazole is an anti-fungal medicine indicated for the treatment of vaginal yeast infections and tinea. It can be used either in combination with other drugs (betamethasone dipropionate) or alone, in form of topical or vaginal cream. The drug exerts its action by inhibiting lanosterol demethylase thereby affecting the growth of fungi.

Originator

Curator's Comment: # Bayer

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
19.7 nM [Kd]
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
GYNE-LOTRIMIN

Approved Use

To treat vaginal yeast infections.

Launch Date

1976
Curative
LOTRISONE

Approved Use

LOTRISONE cream contains a combination of clotrimazole, an azole antifungal, and betamethasone dipropionate, a corticosteroid, and is indicated for the topical treatment of symptomatic inflammatory tinea pedis, tinea cruris, and tinea corporis due to Epidermophyton floccosum, Trichophyton mentagrophytes, and Trichophyton rubrum in patients 17 years and older.

Launch Date

1984
Curative
LOTRISONE

Approved Use

LOTRISONE cream contains a combination of clotrimazole, an azole antifungal, and betamethasone dipropionate, a corticosteroid, and is indicated for the topical treatment of symptomatic inflammatory tinea pedis, tinea cruris, and tinea corporis due to Epidermophyton floccosum, Trichophyton mentagrophytes, and Trichophyton rubrum in patients 17 years and older.

Launch Date

1984
Curative
LOTRISONE

Approved Use

LOTRISONE cream contains a combination of clotrimazole, an azole antifungal, and betamethasone dipropionate, a corticosteroid, and is indicated for the topical treatment of symptomatic inflammatory tinea pedis, tinea cruris, and tinea corporis due to Epidermophyton floccosum, Trichophyton mentagrophytes, and Trichophyton rubrum in patients 17 years and older.

Launch Date

1984
Cmax

Cmax

ValueDoseCo-administeredAnalytePopulation
2.4 μM
1 g single, oral
dose: 1 g
route of administration: Oral
experiment type: SINGLE
co-administered:
CLOTRIMAZOLE plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: FEMALE / MALE
food status: FED
4.98 ng/mL
10 mg single, buccal
dose: 10 mg
route of administration: Buccal
experiment type: SINGLE
co-administered:
CLOTRIMAZOLE serum
Homo sapiens
population: UNKNOWN
age: UNKNOWN
sex: UNKNOWN
food status: UNKNOWN
AUC

AUC

ValueDoseCo-administeredAnalytePopulation
12.59 μM × h
1 g single, oral
dose: 1 g
route of administration: Oral
experiment type: SINGLE
co-administered:
CLOTRIMAZOLE plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: FEMALE / MALE
food status: FED
T1/2

T1/2

ValueDoseCo-administeredAnalytePopulation
2.99 h
1 g single, oral
dose: 1 g
route of administration: Oral
experiment type: SINGLE
co-administered:
CLOTRIMAZOLE plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: FEMALE / MALE
food status: FED
4.25 h
500 mg single, vaginal
dose: 500 mg
route of administration: Vaginal
experiment type: SINGLE
co-administered:
CLOTRIMAZOLE plasma
Homo sapiens
population: UNKNOWN
age: UNKNOWN
sex: FEMALE
food status: UNKNOWN
Doses

Doses

DosePopulationAdverse events​
10 mg 5 times / day multiple, oral
Recommended
Dose: 10 mg, 5 times / day
Route: oral
Route: multiple
Dose: 10 mg, 5 times / day
Sources:
unhealthy, 33 years (range: 22 - 43 years)
Health Status: unhealthy
Age Group: 33 years (range: 22 - 43 years)
Sex: M+F
Sources:
Disc. AE: Nausea, Taste abnormality...
AEs leading to
discontinuation/dose reduction:
Nausea (2 patients)
Taste abnormality (2 patients)
Sources:
500 mg single, vaginal
Highest studied dose
unhealthy, adult
Disc. AE: Vulvovaginal pruritus...
AEs leading to
discontinuation/dose reduction:
Vulvovaginal pruritus (1 patient)
Sources:
500 mg single, vaginal
Highest studied dose
unhealthy, adult
Disc. AE: Vulvovaginal burning sensation...
AEs leading to
discontinuation/dose reduction:
Vulvovaginal burning sensation (1 patient)
Sources:
50 mg 1 times / day multiple, vaginal
Dose: 50 mg, 1 times / day
Route: vaginal
Route: multiple
Dose: 50 mg, 1 times / day
Sources:
unhealthy, adult
Disc. AE: Vaginal irritation, Spotting vaginal...
AEs leading to
discontinuation/dose reduction:
Vaginal irritation (1 patient)
Spotting vaginal (1 patient)
Sources:
AEs

AEs

AESignificanceDosePopulation
Nausea 2 patients
Disc. AE
10 mg 5 times / day multiple, oral
Recommended
Dose: 10 mg, 5 times / day
Route: oral
Route: multiple
Dose: 10 mg, 5 times / day
Sources:
unhealthy, 33 years (range: 22 - 43 years)
Health Status: unhealthy
Age Group: 33 years (range: 22 - 43 years)
Sex: M+F
Sources:
Taste abnormality 2 patients
Disc. AE
10 mg 5 times / day multiple, oral
Recommended
Dose: 10 mg, 5 times / day
Route: oral
Route: multiple
Dose: 10 mg, 5 times / day
Sources:
unhealthy, 33 years (range: 22 - 43 years)
Health Status: unhealthy
Age Group: 33 years (range: 22 - 43 years)
Sex: M+F
Sources:
Vulvovaginal pruritus 1 patient
Disc. AE
500 mg single, vaginal
Highest studied dose
unhealthy, adult
Vulvovaginal burning sensation 1 patient
Disc. AE
500 mg single, vaginal
Highest studied dose
unhealthy, adult
Spotting vaginal 1 patient
Disc. AE
50 mg 1 times / day multiple, vaginal
Dose: 50 mg, 1 times / day
Route: vaginal
Route: multiple
Dose: 50 mg, 1 times / day
Sources:
unhealthy, adult
Vaginal irritation 1 patient
Disc. AE
50 mg 1 times / day multiple, vaginal
Dose: 50 mg, 1 times / day
Route: vaginal
Route: multiple
Dose: 50 mg, 1 times / day
Sources:
unhealthy, adult
Overview

Overview

CYP3A4CYP2C9CYP2D6hERG

Drug as perpetrator​

Drug as perpetrator​

TargetModalityActivityMetaboliteClinical evidence
no
yes [IC50 0.00315 uM]
yes [IC50 0.00822 uM]
yes [IC50 0.1 uM]
yes [IC50 0.745 uM]
yes [IC50 2.3 uM]
yes [IC50 >10 uM]
yes [IC50 >10 uM]
yes [IC50 >10 uM]
yes [IC50 >10 uM]
yes [IC50 >10 uM]
yes [IC50 >10 uM]
yes [IC50 >10 uM]
yes
yes
yes
Tox targets

Tox targets

TargetModalityActivityMetaboliteClinical evidence
PubMed

PubMed

TitleDatePubMed
K+ currents generated by NMDA receptor activation in rat hippocampal pyramidal neurons.
2002-06
Involvement of nitric oxide and potassium channels in the bradykinin-induced vasodilatation in the rat kidney perfused ex situ.
2002-05-30
Inhibition of vascular smooth muscle cell migration by cytochrome p450 epoxygenase-derived eicosanoids.
2002-05-17
Use of intermittent bladder infusion with clotrimazole for treatment of candiduria in a dog.
2002-05-15
Regulation of a calcium-sensitive K+ channel (cIK1) by protein kinase C.
2002-05-01
Translation initiation and its deregulation during tumorigenesis.
2002-04-08
Fluconazole to prevent yeast infections in bone marrow transplantation patients: a randomized trial of high versus reduced dose, and determination of the value of maintenance therapy.
2002-04-01
Dehydration response of sickle cells to sickling-induced Ca(++) permeabilization.
2002-04-01
Clinical comparison of the efficacy and tolerability of once daily Canesten with twice daily Nizoral (clotrimazole 1% cream vs. ketoconazole 2% cream) during a 28-day topical treatment of interdigital tinea pedis.
2002-04
Do azoles and chloroquine share similar mechanisms of antimalarial action?
2002-04
Crystallization and preliminary crystallographic analysis of a novel cytochrome P450 from Mycobacterium tuberculosis.
2002-04
Cytochrome P450 3A conjugation to ubiquitin in a process distinct from classical ubiquitination pathway.
2002-04
Topical antibiotic, antifungal, and antiseptic solutions decrease ciliary activity in nasal respiratory cells.
2002-03-16
The flavonol quercetin activates basolateral K(+) channels in rat distal colon epithelium.
2002-03
Effect of antifungal azoles on the heme detoxification system of malarial parasite.
2002-03
Inhibition of cytochromes P450 by antifungal imidazole derivatives.
2002-03
Clotrimazole/betamethasone diproprionate: a review of costs and complications in the treatment of common cutaneous fungal infections.
2002-02-28
Influence of redox-active compounds and PXR-activators on human MRP1 and MRP2 gene expression.
2002-02-28
Arginine supplementation of sickle transgenic mice reduces red cell density and Gardos channel activity.
2002-02-15
Topical antifungal drug products for over-the-counter human use; amendment of final monograph. Final rule.
2002-02-08
Clotrimazole binds to heme and enhances heme-dependent hemolysis: proposed antimalarial mechanism of clotrimazole.
2002-02-08
Characterization of basolateral K+ channels underlying anion secretion in the human airway cell line Calu-3.
2002-02-01
Modulation of mouse Paneth cell alpha-defensin secretion by mIKCa1, a Ca2+-activated, intermediate conductance potassium channel.
2002-02-01
Clotrimazole-triiodide ion association as an ion exchanger for a triiodide ion-selective electrode.
2002-02
Contribution of cytochrome P450 metabolites to bradykinin-induced vasodilation in endothelial NO synthase deficient mouse hearts.
2002-02
Activation of ion secretion via proteinase-activated receptor-2 in human colon.
2002-02
Spectrofluorimetric determination of vigabatrin and gabapentin in urine and dosage forms through derivatization with fluorescamine.
2002-01-01
Differential pulse polarographic determination of clotrimazole after derivatization with Procion Red HE-3B.
2002-01-01
Comparison of two methods for antifungal susceptibility testing of Trichophyton rubrum.
2002-01
Development of a topical suspension containing three active ingredients.
2002-01
Perianal ulcerations from topical steroid use.
2002-01
A pilot study evaluating the safety and microbiologic efficacy of an economically viable antimicrobial lozenge in patients with head and neck cancer receiving radiation therapy.
2002-01
Adenovirus vector-mediated reporter system for in vivo analyses of human CYP3A4 gene activation.
2002-01
Orphan nuclear receptor binding site in the human inducible nitric oxide synthase promoter mediates responsiveness to steroid and xenobiotic ligands.
2002
Interventions for treating oral candidiasis for patients with cancer receiving treatment.
2002
Toward a novel metal-based chemotherapy against tropical diseases. 6. Synthesis and characterization of new copper(II) and gold(I) clotrimazole and ketoconazole complexes and evaluation of their activity against Trypanosoma cruzi.
2001-12-31
Tinea incognito caused by trichophyton mentagrophytes -- a case report.
2001-12
Effects of clotrimazole on transport mediated by multidrug resistance associated protein 1 (MRP1) in human erythrocytes and tumour cells.
2001-12
Regulation of K(+) current in human airway epithelial cells by exogenous and autocrine adenosine.
2001-12
Outcome of 22 cases of perforated tympanic membrane caused by otomycosis.
2001-11
Otomycosis in Nigeria: treatment with mercurochrome.
2001-11
Novel effects of minocycline on Ca(2+)-dependent Cl(-) secretion in human airway epithelial Calu-3 cells.
2001-10-15
Intracellular signalling involved in activation of the volume-sensitive K+ current in Ehrlich ascites tumour cells.
2001-10
[How I treat ... sickle cell anemia: current therapies].
2001-10
Sertaconazole: in-vitro antifungal activity against vaginal and other superficial yeast isolates.
2001-10
In vitro activity of 6 antifungal agents on candida species isolated as causative agents from vaginal and other clinical specimens.
2001-10
Angiotensin II type AT(2) receptor mRNA expression and renal vasodilatation are increased in renal failure.
2001-09
Swelling-induced K(+) fluxes in vascular smooth muscle cells are mediated by charybdotoxin-sensitive K(+) channels.
2001
[Vulvovaginal candidiasis in childhood--diagnostic and therapeutic results].
2001
Topical treatment for vaginal candidiasis (thrush) in pregnancy.
2001
Patents

Sample Use Guides

In Vivo Use Guide
Curator's Comment: http://www.accessdata.fda.gov/drugsatfda_docs/label/2010/018052Orig1s032lbl.pdf
Vaginal 1% cream: insert an applicator full of cream into the vagina at bedtime for 7 days. External 1% cream for vaginal yeast infections: apply to the skin outside the vagina 2 times daily for up to 7 days. Topical 1% cream: apply a thin layer to the affected area twice daily for 2 weeks (tinea pedis) or 1 week (tinea cruris and tinea corporis).
Route of Administration: Topical
In vitro antifungal activity indicated Clotrimazole (MIC 16 and 8 microg/ml) effective against 68 (70%) of Candida SPP.
Substance Class Chemical
Created
by admin
on Mon Mar 31 17:45:54 GMT 2025
Edited
by admin
on Mon Mar 31 17:45:54 GMT 2025
Record UNII
G07GZ97H65
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
LOTRISONE COMPONENT CLOTRIMAZOLE
Preferred Name English
CLOTRIMAZOLE
EP   GREEN BOOK   HSDB   INCI   INN   MART.   MI   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD  
INN   USAN   INCI  
Official Name English
CLOTRIMAZOLE [GREEN BOOK]
Common Name English
SVT-15652
Code English
CLOTRIMAZOLE [ORANGE BOOK]
Common Name English
GNF-PF-3499
Code English
CLOTRIMAZOLE [USP IMPURITY]
Common Name English
TRIVAGIZOLE
Brand Name English
clotrimazole [INN]
Common Name English
CLOTRIMAZOLE [MART.]
Common Name English
CLOTRIMAZOLE [JAN]
Common Name English
Clotrimazole [WHO-DD]
Common Name English
GYNIX
Brand Name English
BAY-5097
Code English
LOTRIMIN
Brand Name English
CLOTRIMAZOLE [MI]
Common Name English
GYNE-LOTRIMIN
Brand Name English
CLOTRIMAZOLE [EP IMPURITY]
Common Name English
BAY 5097
Code English
1-(2-CHLOROTRITYL)IMIDAZOLE
Systematic Name English
CLOTRIMAZOLE [USP MONOGRAPH]
Common Name English
MYCELEX
Brand Name English
CLOTRIMAZOLE [EP MONOGRAPH]
Common Name English
NSC-257473
Code English
1-(O-CHLORO-.ALPHA.,.ALPHA.-DIPHENYLBENZYL)IMIDAZOLE
Common Name English
CLOTRIMAZOLE [VANDF]
Common Name English
1-((2-CHLOROPHENYL)DIPHENYLMETHYL)-1H-IMIDAZOLE
Systematic Name English
CLOTRIMAZOLE [USAN]
Common Name English
1H-IMIDAZOLE, 1-((2-CHLOROPHENYL)DIPHENYLMETHYL)-
Systematic Name English
CLOTRIMAZOLE [USP-RS]
Common Name English
Classification Tree Code System Code
CFR 21 CFR 524.1044G
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
FDA ORPHAN DRUG 204005
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
WHO-VATC QJ02AB90
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
WHO-VATC QG01AF02
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
NDF-RT N0000008217
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
WHO-ESSENTIAL MEDICINES LIST 6.3
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
CFR 21 CFR 524.450
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
FDA ORPHAN DRUG 216705
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
WHO-VATC QA01AB18
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
FDA ORPHAN DRUG 88094
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
WHO-VATC QD01AC01
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
LIVERTOX NBK548320
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
WHO-ATC D01AC01
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
NDF-RT N0000175487
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
WHO-ATC G01AF02
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
NCI_THESAURUS C514
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
WHO-ATC A01AB18
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
CFR 21 CFR 333.210
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
CFR 21 CFR 524.1044H
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
FDA ORPHAN DRUG 520516
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
Code System Code Type Description
MESH
D003022
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
PRIMARY
IUPHAR
2330
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
PRIMARY
WIKIPEDIA
CLOTRIMAZOLE
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
PRIMARY
ECHA (EC/EINECS)
245-764-8
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
PRIMARY
INN
2912
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
PRIMARY
MERCK INDEX
m3671
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
PRIMARY Merck Index
EPA CompTox
DTXSID7029871
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
PRIMARY
EVMPD
SUB06777MIG
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
PRIMARY
DAILYMED
G07GZ97H65
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
PRIMARY
HSDB
3266
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
PRIMARY
RXCUI
2623
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
PRIMARY RxNorm
NSC
257473
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
PRIMARY
SMS_ID
100000092074
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
PRIMARY
DRUG BANK
DB00257
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
PRIMARY
CHEBI
3764
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
PRIMARY
ALANWOOD
clotrimazole
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
PRIMARY
ChEMBL
CHEMBL104
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
PRIMARY
PUBCHEM
2812
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
PRIMARY
NCI_THESAURUS
C381
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
PRIMARY
CAS
23593-75-1
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
PRIMARY
LACTMED
Clotrimazole
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
PRIMARY
RS_ITEM_NUM
1141002
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
PRIMARY
DRUG CENTRAL
719
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
PRIMARY
FDA UNII
G07GZ97H65
Created by admin on Mon Mar 31 17:45:54 GMT 2025 , Edited by admin on Mon Mar 31 17:45:54 GMT 2025
PRIMARY
Related Record Type Details
METABOLIC ENZYME -> INDUCER
TRANSPORTER -> INHIBITOR
Related Record Type Details
METABOLITE -> PARENT
MAJOR
FECAL; PLASMA; URINE
METABOLITE -> PARENT
MINOR
FECAL; PLASMA; URINE
METABOLITE -> PARENT
MAJOR
FECAL; PLASMA; URINE
Related Record Type Details
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Related Record Type Details
ACTIVE MOIETY