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Details

Stereochemistry ABSOLUTE
Molecular Formula C12H20N2O3S
Molecular Weight 272.364
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DEXSOTALOL

SMILES

CC(C)NC[C@@H](O)C1=CC=C(NS(C)(=O)=O)C=C1

InChI

InChIKey=ZBMZVLHSJCTVON-GFCCVEGCSA-N
InChI=1S/C12H20N2O3S/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17/h4-7,9,12-15H,8H2,1-3H3/t12-/m1/s1

HIDE SMILES / InChI
Molecular Formula C12H20N2O3S
Molecular Weight 272.364
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Dexsotalol is an isomer of antiarrhythmic drug d,l-sotalol, but in opposite to drug, it increases the incidence of arrhythmias

Approval Year

Unknown
149124
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Withdrawn
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
New antiarrhythmic agents for atrial fibrillation and atrial flutter: United States drug market response as an indicator of acceptance.
2003-10
Patents

Patents

US20070116729
21

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:31:35 GMT 2025
Edited
by admin
on Mon Mar 31 19:31:35 GMT 2025
Record UNII
HO7QAP3XEF
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DEXSOTALOL
INN   WHO-DD  
INN  
Official Name English
(+)-SOTALOL
Preferred Name English
SOTALOL, (S)-
Common Name English
Dexsotalol [WHO-DD]
Common Name English
METHANESULFONAMIDE, N-(4-(1-HYDROXY-2-((1-METHYLETHYL)AMINO)ETHYL)PHENYL)-, (S)-
Common Name English
dexsotalol [INN]
Common Name English
SOTALOL, D-
Common Name English
D-SOTALOL
Common Name English
N-(4-((1S)-1-HYDROXY-2-((1-METHYLETHYL)AMINO)ETHYL)PHENYL)METHANESULFONAMIDE
Systematic Name English
(S)-SOTALOL
Common Name English
METHANESULFONANILIDE, 4'-(1-HYDROXY-2-(ISOPROPYLAMINO)ETHYL)-, (+)-
Systematic Name English
L-SOTALOL
Common Name English
METHANESULFONAMIDE, N-(4-((1S)-1-HYDROXY-2-((1-METHYLETHYL)AMINO)ETHYL)PHENYL)-
Systematic Name English
Code System Code Type Description
ChEMBL
CHEMBL252312
Created by admin on Mon Mar 31 19:31:35 GMT 2025 , Edited by admin on Mon Mar 31 19:31:35 GMT 2025
PRIMARY
CAS
30236-32-9
Created by admin on Mon Mar 31 19:31:35 GMT 2025 , Edited by admin on Mon Mar 31 19:31:35 GMT 2025
PRIMARY
EVMPD
SUB07048MIG
Created by admin on Mon Mar 31 19:31:35 GMT 2025 , Edited by admin on Mon Mar 31 19:31:35 GMT 2025
PRIMARY
EPA CompTox
DTXSID2048454
Created by admin on Mon Mar 31 19:31:35 GMT 2025 , Edited by admin on Mon Mar 31 19:31:35 GMT 2025
PRIMARY
NCI_THESAURUS
C169900
Created by admin on Mon Mar 31 19:31:36 GMT 2025 , Edited by admin on Mon Mar 31 19:31:36 GMT 2025
PRIMARY
FDA UNII
HO7QAP3XEF
Created by admin on Mon Mar 31 19:31:36 GMT 2025 , Edited by admin on Mon Mar 31 19:31:36 GMT 2025
PRIMARY
INN
7455
Created by admin on Mon Mar 31 19:31:35 GMT 2025 , Edited by admin on Mon Mar 31 19:31:35 GMT 2025
PRIMARY
SMS_ID
100000083433
Created by admin on Mon Mar 31 19:31:36 GMT 2025 , Edited by admin on Mon Mar 31 19:31:36 GMT 2025
PRIMARY
PUBCHEM
119259
Created by admin on Mon Mar 31 19:31:35 GMT 2025 , Edited by admin on Mon Mar 31 19:31:35 GMT 2025
PRIMARY
Related Record Type Details
Structure of DEXSOTALOL HYDROCHLORIDE
SALT/SOLVATE -> PARENT
Structure of SOTALOL
RACEMATE -> ENANTIOMER
Related Record Type Details
Structure of DEXSOTALOL
ACTIVE MOIETY
NIH
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