Briquilimab

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 22:54:46 GMT 2025` Edited by `admin` on `Tue Apr 01 22:54:46 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	QWX84D0DRC
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Briquilimab

Official Name

English

AMG-191

Preferred Name

English

briquilimab [INN]

Common Name

English

JSP191

Code

English

BRIQUILIMAB [USAN]

Common Name

English

JSP-191

Code

English

IMMUNOGLOBULIN G1 (297-GLUTAMINE), ANTI-(HUMAN C-KIT RECEPTOR) (HUMAN-MUS MUSCULUS MONOCLONAL JSP191 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL JSP191 .KAPPA.-CHAIN, DIMER

Common Name

English

AMG191

Code

English

Classification Tree Code System Code

FDA ORPHAN DRUG

820121

Created by admin on Tue Apr 01 22:54:46 GMT 2025 , Edited by admin on Tue Apr 01 22:54:46 GMT 2025

Code System Code Type Description

CAS

2574591-89-0

Created by admin on Tue Apr 01 22:54:46 GMT 2025 , Edited by admin on Tue Apr 01 22:54:46 GMT 2025

PRIMARY

FDA UNII

QWX84D0DRC

Created by admin on Tue Apr 01 22:54:46 GMT 2025 , Edited by admin on Tue Apr 01 22:54:46 GMT 2025

PRIMARY

SMS_ID

300000040551

Created by admin on Tue Apr 01 22:54:46 GMT 2025 , Edited by admin on Tue Apr 01 22:54:46 GMT 2025

PRIMARY

NCI_THESAURUS

C174050

Created by admin on Tue Apr 01 22:54:46 GMT 2025 , Edited by admin on Tue Apr 01 22:54:46 GMT 2025

PRIMARY

USAN

LM-13

Created by admin on Tue Apr 01 22:54:46 GMT 2025 , Edited by admin on Tue Apr 01 22:54:46 GMT 2025

PRIMARY

INN

12124

Created by admin on Tue Apr 01 22:54:46 GMT 2025 , Edited by admin on Tue Apr 01 22:54:46 GMT 2025

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_144	2_200
2_220	4_218
2_261	2_321
1_144	1_200
2_367	2_425
3_23	3_92
3_138	3_198
4_23	4_92
4_138	4_198
1_220	3_218
1_226	2_226
1_229	2_229
1_261	1_321
1_367	1_425

Related Record Type Details


					OVI08ABI5H

MAST/STEM CELL GROWTH FACTOR RECEPTOR KIT

TARGET -> INHIBITOR

Interaction Type:

BINDING

Qualification:

Kd

Amount:

Related Record Type Details


					QWX84D0DRC

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]	N-TERMINUS			PIDOLIC ACID	SZB83O1W42
AMINO ACID REMOVAL	[1_447] [2_447]				LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL