ANBENITAMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 00:07:04 GMT 2025` Edited by `admin` on `Wed Apr 02 00:07:04 GMT 2025`
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	RHS90QRF9E
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

KN-026

Preferred Name

English

ANBENITAMAB

Official Name

English

ANTI-HER2 BSAB KN026

Common Name

English

KN 026 [WHO-DD]

Common Name

English

anbenitamab [INN]

Common Name

English

IMMUNOGLOBULIN G1 (369-SERINE,371-ALANINE,408-LYSINE,410-VALINE), ANTI-(HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR HER2 DOMAIN IV)(HUMAN-MUS MUSCULUS MONOCLONAL RHUMAB 4D5 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL RHUMAB 4D5 .KAPPA.-CHAIN

Common Name

English

KN026

Code

English

Classification Tree Code System Code

FDA ORPHAN DRUG

786920

Created by admin on Wed Apr 02 00:07:04 GMT 2025 , Edited by admin on Wed Apr 02 00:07:04 GMT 2025

Code System Code Type Description

CAS

2367012-88-0

Created by admin on Wed Apr 02 00:07:04 GMT 2025 , Edited by admin on Wed Apr 02 00:07:04 GMT 2025

PRIMARY

FDA UNII

RHS90QRF9E

Created by admin on Wed Apr 02 00:07:04 GMT 2025 , Edited by admin on Wed Apr 02 00:07:04 GMT 2025

PRIMARY

NCI_THESAURUS

C162577

Created by admin on Wed Apr 02 00:07:04 GMT 2025 , Edited by admin on Wed Apr 02 00:07:04 GMT 2025

PRIMARY

INN

11611

Created by admin on Wed Apr 02 00:07:04 GMT 2025 , Edited by admin on Wed Apr 02 00:07:04 GMT 2025

PRIMARY

INN

SMS_ID

300000032298

Created by admin on Wed Apr 02 00:07:04 GMT 2025 , Edited by admin on Wed Apr 02 00:07:04 GMT 2025

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_146	2_202
2_263	2_323
1_147	1_203
3_23	3_88
4_23	4_88
1_229	2_228
1_232	2_231
1_264	1_324
1_370	1_428
2_222	4_214
1_223	3_214
2_369	2_427
3_134	3_194
4_134	4_194

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_300
N	2_299

Related Record Type Details


					7J9Y28299R

RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2

TARGET -> INHIBITOR

Amount:


					3U4SXA9ADW

Anbenitamab Repodatecan

CONJUGATE -> PARENT

Amount:

Related Record Type Details


					RHS90QRF9E

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_450] [2_449]	C-TERMINUS			LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL