U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Mon Mar 31 23:10:25 GMT 2025
Edited
by admin
on Mon Mar 31 23:10:25 GMT 2025
Protein Type ENZYME
Protein Sub Type SERINE/THREONINE-PROTEIN KINASE
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
S54X4ZF5K5
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BRAF
Preferred Name English
SERINE/THREONINE-PROTEIN KINASE B-RAF
Common Name English
BRAF1
Common Name English
V-RAF MURINE SARCOMA VIRAL ONCOGENE HOMOLOG B
Common Name English
P94
Common Name English
NS7 KINASE
Common Name English
PROTO-ONCOGENE B-RAF
Common Name English
Code System Code Type Description
UNIPROT
P15056
Created by admin on Mon Mar 31 23:10:25 GMT 2025 , Edited by admin on Mon Mar 31 23:10:25 GMT 2025
PRIMARY
FDA UNII
S54X4ZF5K5
Created by admin on Mon Mar 31 23:10:25 GMT 2025 , Edited by admin on Mon Mar 31 23:10:25 GMT 2025
PRIMARY
Related Record Type Details
Serine/threonine-protein kinase B-raf V600K
MUTANT->PARENT
Structure of ENCORAFENIB
INHIBITOR -> TARGET
IC50
Structure of Plixorafenib
INHIBITOR -> TARGET
Structure of SORAFENIB
INHIBITOR -> TARGET
Structure of Mosperafenib
INHIBITOR -> TARGET
Structure of RIPRETINIB
INHIBITOR -> TARGET
IN VITRO
Structure of BELVARAFENIB
INHIBITOR -> TARGET
Structure of Avutometinib
INHIBITOR -> TARGET
Structure of REGORAFENIB ANHYDROUS
INHIBITOR -> TARGET
Structure of AGERAFENIB
INHIBITOR -> TARGET
Structure of Tovorafenib
INHIBITOR -> TARGET
Structure of LY-3009120
INHIBITOR -> TARGET
IC50
Structure of Tinlorafenib
INHIBITOR -> TARGET
IN-VITRO
Structure of XP-102
INHIBITOR -> TARGET
PRECLINICAL
Structure of Naporafenib
INHIBITOR -> TARGET
IC50
Structure of LIFIRAFENIB
INHIBITOR -> TARGET
Structure of LUT-017
INHIBITOR -> TARGET
Structure of [2,4?-Bipyridine]-2?-carboxamide, 4-[5-[[[2-(1-fluoro-1-methylethyl)-4-pyridinyl]carbonyl]amino]-2-methylphenyl]-
INHIBITOR -> TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
PRIVACY NOTICE
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966