LML-134

Details

Stereochemistry	ACHIRAL
Molecular Formula	C19H29N5O3
Molecular Weight	375.4653
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN1N=C(C=CC1=O)N2CCC(CC2)OC(=O)N3CCN(CC3)C4CCC4

InChI

InChIKey=BVUJMFFRMZRNAT-UHFFFAOYSA-N

InChI=1S/C19H29N5O3/c1-21-18(25)6-5-17(20-21)23-9-7-16(8-10-23)27-19(26)24-13-11-22(12-14-24)15-3-2-4-15/h5-6,15-16H,2-4,7-14H2,1H3

HIDE SMILES / InChI

Molecular Formula	C19H29N5O3
Molecular Weight	375.4653
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Tue Apr 01 20:49:21 GMT 2025` Edited by `admin` on `Tue Apr 01 20:49:21 GMT 2025`
Record UNII	UM4TJY3PCY
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

LML-134

Code

English

LML134

Preferred Name

English

1-PIPERAZINECARBOXYLIC ACID, 4-CYCLOBUTYL-, 1-(1,6-DIHYDRO-1-METHYL-6-OXO-3-PYRIDAZINYL)-4-PIPERIDINYL ESTER

Systematic Name

English

Code System Code Type Description

FDA UNII

UM4TJY3PCY

Created by admin on Tue Apr 01 20:49:21 GMT 2025 , Edited by admin on Tue Apr 01 20:49:21 GMT 2025

PRIMARY

SMS_ID

300000042531

Created by admin on Tue Apr 01 20:49:21 GMT 2025 , Edited by admin on Tue Apr 01 20:49:21 GMT 2025

PRIMARY

PUBCHEM

72948400

Created by admin on Tue Apr 01 20:49:21 GMT 2025 , Edited by admin on Tue Apr 01 20:49:21 GMT 2025

PRIMARY

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HISTAMINE H3 RECEPTOR

TARGET->INVERSE AGONIST

Interaction Type:

BINDING

Qualification:

Ki

Amount:


					D9SCP0G3HF

HISTAMINE H3 RECEPTOR

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Comments:

cAMP functional assay

Qualification:

Ki

Amount:


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OFF TARGET->NON-INHIBITOR

Comments:

6% inhibition at 10 micromolar

Qualification:

IC50

Amount:

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					UM4TJY3PCY

LML-134

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
BRAIN/PLASMA RATIO	PHARMACOKINETIC				Species BIOLOGICAL