DOPAMINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H11NO2
Molecular Weight	153.1784
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of DOPAMINE

Structure Search

SMILES

NCCC1=CC(O)=C(O)C=C1

InChI

InChIKey=VYFYYTLLBUKUHU-UHFFFAOYSA-N

InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2

HIDE SMILES / InChI

Molecular Formula	C8H11NO2
Molecular Weight	153.1784
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:09:29 UTC 2023` Edited by `admin` on `Fri Dec 15 15:09:29 UTC 2023`
Record UNII	VTD58H1Z2X
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

DOPAMINE

Official Name

English

MEDOPA

Brand Name

English

4-(2-AMINOETHYL)PYROCATECHOL

Systematic Name

English

NORADRENALINE TARTRATE IMPURITY C [EP IMPURITY]

Common Name

English

DOBUTAMINE A

Common Name

English

DOBUTAMINE HYDROCHLORIDESPECIFIED IMPURITY A [EP IMPURITY]

Common Name

English

dopamine [INN]

Common Name

English

A-DOPAMINE

Common Name

English

DOPAMINE [VANDF]

Common Name

English

HYDROXYTYRAMINE

Systematic Name

English

OXYTYRAMINE

Common Name

English

DOPAMINE [MI]

Common Name

English

Dopamine [WHO-DD]

Common Name

English

1,2-BENZENEDIOL, 4-(2-AMINOETHYL)-

Systematic Name

English

DOBUTAMINE HYDROCHLORIDE IMPURITY A [EP IMPURITY]

Common Name

English

NSC-173182

Code

English

DOPAMINE [HSDB]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C88516

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

LOINC

13733-1

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

DSLD

4132 (Number of products:1)

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

NDF-RT

N0000007715

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

LOINC

14703-3

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

LOINC

15058-1

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

LOINC

25906-9

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

WHO-ESSENTIAL MEDICINES LIST

12.4

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

LOINC

2217-8

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

LOINC

24524-1

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

LOINC

2218-6

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

LOINC

2216-0

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

LOINC

44316-8

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

LOINC

15059-9

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

WHO-ATC

C01CA04

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

LOINC

33873-1

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

LOINC

74904-4

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

NDF-RT

N0000175570

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

LOINC

27212-0

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

WHO-VATC

QC01CA04

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

LOINC

44918-1

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

Code System Code Type Description

MESH

D004298

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

PRIMARY

EPA CompTox

DTXSID6022420

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

PRIMARY

DAILYMED

VTD58H1Z2X

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

PRIMARY

WIKIPEDIA

Dopamine (medication)

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

PRIMARY

ECHA (EC/EINECS)

200-110-0

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

PRIMARY

WIKIPEDIA

DOPAMINE

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

PRIMARY

NCI_THESAURUS

C62025

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

PRIMARY

SMS_ID

100000080782

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

PRIMARY

PUBCHEM

681

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

PRIMARY

HSDB

3068

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

PRIMARY

ChEMBL

CHEMBL59

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

PRIMARY

FDA UNII

VTD58H1Z2X

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

PRIMARY

RXCUI

3628

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

PRIMARY

RxNorm

MERCK INDEX

m4740

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

PRIMARY

Merck Index

CHEBI

59905

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

PRIMARY

IUPHAR

940

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

PRIMARY

NSC

173182

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

PRIMARY

LACTMED

Dopamine

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

PRIMARY

INN

2417

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

PRIMARY

DRUG BANK

DB00988

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

PRIMARY

CAS

51-61-6

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

PRIMARY

DRUG CENTRAL

947

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

PRIMARY

EVMPD

SUB06365MIG

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

PRIMARY

CHEBI

18243

Created by admin on Fri Dec 15 15:09:29 UTC 2023 , Edited by admin on Fri Dec 15 15:09:29 UTC 2023

PRIMARY

Related Record Type Details


					F202H3PMO2

SODIUM-DEPENDENT DOPAMINE TRANSPORTER

TRANSPORTER -> SUBSTRATE

Interaction Type:

BINDING

Qualification:

IC50

Amount:


					19GBD6T9L7

D(2) DOPAMINE RECEPTOR

TARGET -> AGONIST

Comments:

D2R concentration levels were significantly lower in AD patients than in healthy controls (SMD = −1.13, 95%CI: −1.52 to −0.74), with low heterogeneity (I2 = 7.80%), when USA studies were considered.

Amount:


					XZC6H8R666

CYTISUS SCOPARIUS FLOWERING TOP

CONSTITUENT ALWAYS PRESENT -> PARENT

Amount:


					9RPS2XD496

DOPAMINE BETA-HYDROXYLASE, SOLUBLE

METABOLIC ENZYME -> SUBSTRATE

Amount:


					ONY583280Z

OCT-1

TRANSPORTER -> SUBSTRATE

Amount:


					B5QXZ49C7Y

AMINE OXIDASE (FLAVIN-CONTAINING) A

METABOLIC ENZYME -> SUBSTRATE

Amount:


					285VE60914

6-APB

ACTIVATOR OF RELEASE->TARGET

Amount:


					22Q832K2UN

CATECHOL O-METHYLTRANSFERASE

METABOLIC ENZYME -> SUBSTRATE

Amount:


					7L3E358N9L

DOPAMINE HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Amount:

Related Record Type Details


					7WX5W6GM6F

3-METHOXYPHENYLETHYLAMINE

METABOLITE -> PARENT

Amount:


					RPQ57D8S72

PRODRUG -> METABOLITE ACTIVE

Qualification:

PLASMA; URINE

Amount:


					46627O600J

LEVODOPA

PRODRUG -> METABOLITE ACTIVE

Interaction Type:

MAJOR

Amount:


					JCH2767EDP

3-O-METHYLDOPAMINE

METABOLITE INACTIVE -> PARENT

Amount:


					8HW4YBZ748

METABOLITE TOXIC -> PARENT

Amount:


					46627O600J

LEVODOPA

PRODRUG -> METABOLITE ACTIVE

Amount:


					X8ZC7V0OX3

TYRAMINE

PARENT -> METABOLITE ACTIVE

Interaction Type:

MINOR

Amount:


					F2E9Q24TSL

Dopal

METABOLITE TOXIC -> PARENT

Amount:


					37NQZ0J76I

PRODRUG -> METABOLITE ACTIVE

Amount:


					Z3OC8499KG

DIHYDROXYINDOLE

METABOLITE -> PARENT

Amount:

Related Record Type Details


					0WR771DJXV

DOBUTAMINE HYDROCHLORIDE

PARENT -> IMPURITY

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					IFY5PE3ZRW

NOREPINEPHRINE BITARTRATE

PARENT -> IMPURITY

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:

Related Record Type Details


					VTD58H1Z2X

DOPAMINE

ACTIVE MOIETY

Amount: