ASFOTASE ALFA

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 19:56:27 GMT 2025` Edited by `admin` on `Mon Mar 31 19:56:27 GMT 2025`
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	Z633861EIM
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ASFOTASE ALFA

Official Name

English

asfotase alfa [INN]

Preferred Name

English

ALXN-1215

Code

English

ASFOTASE ALFA [USAN]

Common Name

English

Asfotase alfa [WHO-DD]

Common Name

English

TISSUE-NONSPECIFIC ALKALINE PHOSPHATASE- IGG1 FUSION PROTEIN

Common Name

English

ASFOTASE ALFA [MI]

Common Name

English

PHOSPHATASE, ALKALINE (SYNTHETIC HUMAN TISSUE-NONSPECIFIC ISOENZYME ENB-0040)

Systematic Name

English

ASFOTASE ALFA [PURPLE BOOK CDER]

Common Name

English

ASFOTASE ALFA [JAN]

Common Name

English

ALXN1215

Code

English

ENB-0040

Code

English

STRENSIQ

Brand Name

English

Classification Tree Code System Code

EU-Orphan Drug

EU/3/08/594

Created by admin on Mon Mar 31 19:56:27 GMT 2025 , Edited by admin on Mon Mar 31 19:56:27 GMT 2025

NDF-RT

N0000191865

Created by admin on Mon Mar 31 19:56:27 GMT 2025 , Edited by admin on Mon Mar 31 19:56:27 GMT 2025

FDA ORPHAN DRUG

266608

Created by admin on Mon Mar 31 19:56:27 GMT 2025 , Edited by admin on Mon Mar 31 19:56:27 GMT 2025

WHO-ATC

A16AB13

Created by admin on Mon Mar 31 19:56:27 GMT 2025 , Edited by admin on Mon Mar 31 19:56:27 GMT 2025

Code System Code Type Description

EVMPD

SUB168381

Created by admin on Mon Mar 31 19:56:27 GMT 2025 , Edited by admin on Mon Mar 31 19:56:27 GMT 2025

PRIMARY

DRUG CENTRAL

5049

Created by admin on Mon Mar 31 19:56:27 GMT 2025 , Edited by admin on Mon Mar 31 19:56:27 GMT 2025

PRIMARY

FDA UNII

Z633861EIM

Created by admin on Mon Mar 31 19:56:27 GMT 2025 , Edited by admin on Mon Mar 31 19:56:27 GMT 2025

PRIMARY

DRUG BANK

DB09105

Created by admin on Mon Mar 31 19:56:27 GMT 2025 , Edited by admin on Mon Mar 31 19:56:27 GMT 2025

PRIMARY

USAN

AB-112

Created by admin on Mon Mar 31 19:56:27 GMT 2025 , Edited by admin on Mon Mar 31 19:56:27 GMT 2025

PRIMARY

ChEMBL

CHEMBL2108311

Created by admin on Mon Mar 31 19:56:27 GMT 2025 , Edited by admin on Mon Mar 31 19:56:27 GMT 2025

PRIMARY

SMS_ID

100000158330

Created by admin on Mon Mar 31 19:56:27 GMT 2025 , Edited by admin on Mon Mar 31 19:56:27 GMT 2025

PRIMARY

MERCK INDEX

m11899

Created by admin on Mon Mar 31 19:56:27 GMT 2025 , Edited by admin on Mon Mar 31 19:56:27 GMT 2025

PRIMARY

NDF-RT

N0000167654

Created by admin on Mon Mar 31 19:56:27 GMT 2025 , Edited by admin on Mon Mar 31 19:56:27 GMT 2025

PRIMARY

Alkaline Phosphatase [Chemical/Ingredient]

WIKIPEDIA

Asfotase alfa

Created by admin on Mon Mar 31 19:56:27 GMT 2025 , Edited by admin on Mon Mar 31 19:56:27 GMT 2025

PRIMARY

CAS

1174277-80-5

Created by admin on Mon Mar 31 19:56:27 GMT 2025 , Edited by admin on Mon Mar 31 19:56:27 GMT 2025

PRIMARY

INN

9269

Created by admin on Mon Mar 31 19:56:27 GMT 2025 , Edited by admin on Mon Mar 31 19:56:27 GMT 2025

PRIMARY

RXCUI

1720259

Created by admin on Mon Mar 31 19:56:27 GMT 2025 , Edited by admin on Mon Mar 31 19:56:27 GMT 2025

PRIMARY

RxNorm

NCI_THESAURUS

C169788

Created by admin on Mon Mar 31 19:56:27 GMT 2025 , Edited by admin on Mon Mar 31 19:56:27 GMT 2025

PRIMARY

DAILYMED

Z633861EIM

Created by admin on Mon Mar 31 19:56:27 GMT 2025 , Edited by admin on Mon Mar 31 19:56:27 GMT 2025

PRIMARY

From	To
1_122	1_184
1_472	1_480
1_493	2_493
1_496	2_496
1_528	1_588
1_634	1_692
2_122	2_184
2_472	2_480
2_528	2_588
2_634	2_692

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_123
N	1_213
N	1_254
N	1_286
N	1_413
N	1_564
N	2_123
N	2_213
N	2_254
N	2_286
N	2_413
N	2_564

Related Record Type Details


					G72T8FL60W

SPHINGOSINE 1-PHOSPHATE RECEPTOR 1

TARGET -> AGONIST


					N3W8UZM18I

ALKALINE PHOSPHATASE, TISSUE-NONSPECIFIC ISOZYME

TARGET->ENZYME REPLACEMENT

Amount:

Related Record Type Details


					Z633861EIM

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:ESTIMATE(SDS-PAGE)	CHEMICAL
Biological Half-life	PHARMACOKINETIC