PROPAFENONE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C21H27NO3
Molecular Weight	341.444
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PROPAFENONE

Structure Search

SMILES

CCCNCC(O)COC1=C(C=CC=C1)C(=O)CCC2=CC=CC=C2

InChI

InChIKey=JWHAUXFOSRPERK-UHFFFAOYSA-N

InChI=1S/C21H27NO3/c1-2-14-22-15-18(23)16-25-21-11-7-6-10-19(21)20(24)13-12-17-8-4-3-5-9-17/h3-11,18,22-23H,2,12-16H2,1H3

HIDE SMILES / InChI

Molecular Formula	C21H27NO3
Molecular Weight	341.444
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:30:38 UTC 2023` Edited by `admin` on `Fri Dec 15 15:30:38 UTC 2023`
Record UNII	68IQX3T69U
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

PROPAFENONE

Official Name

English

PROPAFENONE [MI]

Common Name

English

PROPAFENON HEXAL

Brand Name

English

PROPAFENONE [INCI]

Common Name

English

PROPAFENONE [VANDF]

Common Name

English

Propafenone [WHO-DD]

Common Name

English

propafenone [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C93038

Created by admin on Fri Dec 15 15:30:38 UTC 2023 , Edited by admin on Fri Dec 15 15:30:38 UTC 2023

LIVERTOX

NBK548005

Created by admin on Fri Dec 15 15:30:38 UTC 2023 , Edited by admin on Fri Dec 15 15:30:38 UTC 2023

NDF-RT

N0000175426

Created by admin on Fri Dec 15 15:30:38 UTC 2023 , Edited by admin on Fri Dec 15 15:30:38 UTC 2023

NCI_THESAURUS

C47793

Created by admin on Fri Dec 15 15:30:38 UTC 2023 , Edited by admin on Fri Dec 15 15:30:38 UTC 2023

WHO-VATC

QC01BC03

Created by admin on Fri Dec 15 15:30:38 UTC 2023 , Edited by admin on Fri Dec 15 15:30:38 UTC 2023

WHO-ATC

C01BC03

Created by admin on Fri Dec 15 15:30:38 UTC 2023 , Edited by admin on Fri Dec 15 15:30:38 UTC 2023

Code System Code Type Description

EPA CompTox

DTXSID9045184

Created by admin on Fri Dec 15 15:30:38 UTC 2023 , Edited by admin on Fri Dec 15 15:30:38 UTC 2023

PRIMARY

DRUG BANK

DB01182

Created by admin on Fri Dec 15 15:30:38 UTC 2023 , Edited by admin on Fri Dec 15 15:30:38 UTC 2023

PRIMARY

IUPHAR

2561

Created by admin on Fri Dec 15 15:30:38 UTC 2023 , Edited by admin on Fri Dec 15 15:30:38 UTC 2023

PRIMARY

DRUG CENTRAL

2291

Created by admin on Fri Dec 15 15:30:38 UTC 2023 , Edited by admin on Fri Dec 15 15:30:38 UTC 2023

PRIMARY

ECHA (EC/EINECS)

258-955-6

Created by admin on Fri Dec 15 15:30:38 UTC 2023 , Edited by admin on Fri Dec 15 15:30:38 UTC 2023

PRIMARY

WIKIPEDIA

PROPAFENONE

Created by admin on Fri Dec 15 15:30:38 UTC 2023 , Edited by admin on Fri Dec 15 15:30:38 UTC 2023

PRIMARY

ChEMBL

CHEMBL631

Created by admin on Fri Dec 15 15:30:38 UTC 2023 , Edited by admin on Fri Dec 15 15:30:38 UTC 2023

PRIMARY

FDA UNII

68IQX3T69U

Created by admin on Fri Dec 15 15:30:38 UTC 2023 , Edited by admin on Fri Dec 15 15:30:38 UTC 2023

PRIMARY

LACTMED

Propafenone

Created by admin on Fri Dec 15 15:30:38 UTC 2023 , Edited by admin on Fri Dec 15 15:30:38 UTC 2023

PRIMARY

PUBCHEM

4932

Created by admin on Fri Dec 15 15:30:38 UTC 2023 , Edited by admin on Fri Dec 15 15:30:38 UTC 2023

PRIMARY

RXCUI

8754

Created by admin on Fri Dec 15 15:30:38 UTC 2023 , Edited by admin on Fri Dec 15 15:30:38 UTC 2023

PRIMARY

RxNorm

CAS

54063-53-5

Created by admin on Fri Dec 15 15:30:38 UTC 2023 , Edited by admin on Fri Dec 15 15:30:38 UTC 2023

PRIMARY

SMS_ID

100000081149

Created by admin on Fri Dec 15 15:30:38 UTC 2023 , Edited by admin on Fri Dec 15 15:30:38 UTC 2023

PRIMARY

CHEBI

63619

Created by admin on Fri Dec 15 15:30:38 UTC 2023 , Edited by admin on Fri Dec 15 15:30:38 UTC 2023

PRIMARY

HSDB

7929

Created by admin on Fri Dec 15 15:30:38 UTC 2023 , Edited by admin on Fri Dec 15 15:30:38 UTC 2023

PRIMARY

INN

3312

Created by admin on Fri Dec 15 15:30:38 UTC 2023 , Edited by admin on Fri Dec 15 15:30:38 UTC 2023

PRIMARY

MERCK INDEX

m9178

Created by admin on Fri Dec 15 15:30:38 UTC 2023 , Edited by admin on Fri Dec 15 15:30:38 UTC 2023

PRIMARY

Merck Index

MESH

D011405

Created by admin on Fri Dec 15 15:30:38 UTC 2023 , Edited by admin on Fri Dec 15 15:30:38 UTC 2023

PRIMARY

NCI_THESAURUS

C61909

Created by admin on Fri Dec 15 15:30:38 UTC 2023 , Edited by admin on Fri Dec 15 15:30:38 UTC 2023

PRIMARY

DAILYMED

68IQX3T69U

Created by admin on Fri Dec 15 15:30:38 UTC 2023 , Edited by admin on Fri Dec 15 15:30:38 UTC 2023

PRIMARY

EVMPD

SUB10094MIG

Created by admin on Fri Dec 15 15:30:38 UTC 2023 , Edited by admin on Fri Dec 15 15:30:38 UTC 2023

PRIMARY

Related Record Type Details


					482M00274D

OCT-2

TRANSPORTER -> INHIBITOR


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND


					LR0F81F33L

ALDEHYDE OXIDASE

METABOLIC ENZYME -> INHIBITOR

Qualification:

IC50

Amount:


					33XCH0HOCD

PROPAFENONE HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Related Record Type Details


					KN087PHW5T

N-DEPROPYLPROPAFENONE

METABOLITE ACTIVE -> PARENT


					KN087PHW5T

N-DEPROPYLPROPAFENONE

METABOLITE ACTIVE -> PARENT


					7AC8BF38NP

5-HYDROXYPROPAFENONE

METABOLITE ACTIVE -> PARENT

Related Record Type Details


					68IQX3T69U

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC				Elimination PHARMACOKINETIC Elimination PHARMACOKINETIC

Volume of Distribution	PHARMACOKINETIC				Population PHARMACOKINETIC