EMACTUZUMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 23:43:35 GMT 2025` Edited by `admin` on `Mon Mar 31 23:43:35 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	6FY6EI1X8R
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

EMACTUZUMAB

Official Name

English

emactuzumab [INN]

Preferred Name

English

RO5509554

Code

English

IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS CSF1R (COLONY STIMULATING FACTOR 1 RECEPTOR, CSF-1R, CSF-1-R, MACROPHAGE COLONYSTIMULATING FACTOR 1 RECEPTOR, C-FMS, FMS, CD115)), HUMANIZED MONOCLONAL ANTIBODY

Common Name

English

RO5509554 (ANTI-CSF-R1)

Code

English

RO-5509554

Code

English

7I1955N5WX

Common Name

English

CXD-301

Code

English

EMACTUZUMAB [USAN]

Common Name

English

Emactuzumab [WHO-DD]

Common Name

English

RG-7155

Code

English

RG7155

Code

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN MACROPHAGE COLONY-STIMULATING FACTOR RECEPTOR) (HUMAN-MUS MUSCULUS MONOCLONAL HEAVY CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL LIGHT CHAIN, DIMER

Systematic Name

English

CXD301

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C20401

Created by admin on Mon Mar 31 23:43:35 GMT 2025 , Edited by admin on Mon Mar 31 23:43:35 GMT 2025

FDA ORPHAN DRUG

431614

Created by admin on Mon Mar 31 23:43:35 GMT 2025 , Edited by admin on Mon Mar 31 23:43:35 GMT 2025

Code System Code Type Description

CAS

1448221-67-7

Created by admin on Mon Mar 31 23:43:35 GMT 2025 , Edited by admin on Mon Mar 31 23:43:35 GMT 2025

PRIMARY

LEGACY_FDA_UNII

7I1955N5WX

Created by admin on Mon Mar 31 23:43:35 GMT 2025 , Edited by admin on Mon Mar 31 23:43:35 GMT 2025

PRIMARY

WIKIPEDIA

Emactuzumab

Created by admin on Mon Mar 31 23:43:35 GMT 2025 , Edited by admin on Mon Mar 31 23:43:35 GMT 2025

PRIMARY

ChEMBL

CHEMBL2109324

Created by admin on Mon Mar 31 23:43:35 GMT 2025 , Edited by admin on Mon Mar 31 23:43:35 GMT 2025

PRIMARY

INN

9951

Created by admin on Mon Mar 31 23:43:35 GMT 2025 , Edited by admin on Mon Mar 31 23:43:35 GMT 2025

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EVMPD

SUB177212

Created by admin on Mon Mar 31 23:43:35 GMT 2025 , Edited by admin on Mon Mar 31 23:43:35 GMT 2025

PRIMARY

USAN

CD-102

Created by admin on Mon Mar 31 23:43:35 GMT 2025 , Edited by admin on Mon Mar 31 23:43:35 GMT 2025

PRIMARY

DRUG BANK

DB14905

Created by admin on Mon Mar 31 23:43:35 GMT 2025 , Edited by admin on Mon Mar 31 23:43:35 GMT 2025

PRIMARY

FDA UNII

6FY6EI1X8R

Created by admin on Mon Mar 31 23:43:35 GMT 2025 , Edited by admin on Mon Mar 31 23:43:35 GMT 2025

PRIMARY

ChEMBL

CHEMBL3545370

Created by admin on Mon Mar 31 23:43:35 GMT 2025 , Edited by admin on Mon Mar 31 23:43:35 GMT 2025

PRIMARY

NCI_THESAURUS

C125548

Created by admin on Mon Mar 31 23:43:35 GMT 2025 , Edited by admin on Mon Mar 31 23:43:35 GMT 2025

PRIMARY

SMS_ID

100000163086

Created by admin on Mon Mar 31 23:43:35 GMT 2025 , Edited by admin on Mon Mar 31 23:43:35 GMT 2025

PRIMARY

From	To
1_22	1_95
1_143	1_199
1_260	1_320
1_366	1_424
2_22	2_95
2_143	2_199
2_260	2_320
2_366	2_424
3_23	3_88
3_133	3_193
4_23	4_88
4_133	4_193
1_219	3_213
2_219	4_213
1_225	2_225
1_228	2_228

Glycosylation Link Type	Site
N	1_296
N	2_296

Related Record Type Details


					2VXO9I489U

MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					6FY6EI1X8R

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_1] [2_1]		GLUTAMINE	Amount:	PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER AVERAGE(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL