DRONABINOL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C21H30O2
Molecular Weight	314.4617
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of DRONABINOL

Structure Search

SMILES

[H][C@@]12CCC(C)=C[C@@]1([H])C3=C(O)C=C(CCCCC)C=C3OC2(C)C

InChI

InChIKey=CYQFCXCEBYINGO-IAGOWNOFSA-N

InChI=1S/C21H30O2/c1-5-6-7-8-15-12-18(22)20-16-11-14(2)9-10-17(16)21(3,4)23-19(20)13-15/h11-13,16-17,22H,5-10H2,1-4H3/t16-,17-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C21H30O2
Molecular Weight	314.4617
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:01:16 UTC 2023` Edited by `admin` on `Fri Dec 15 15:01:16 UTC 2023`
Record UNII	7J8897W37S
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

DRONABINOL

Official Name

English

.DELTA.1-THC

Common Name

English

MARINOL

Brand Name

English

QCD 84924

Code

English

ABBOTT 40566

Code

English

THC

Common Name

English

SP 104

Code

English

TETRAHYDROCANNABINOLS (-)-TRANS-.DELTA.9-FORM

Common Name

English

TETRAHYDROCANNABINOL

Common Name

English

(6AR,10AR)-6,6,9-TRIMETHYL-3-PENTYL-6A,7,8,10A-TETRAHYDRO-6H-DIBENZO(B,D)PYRAN-1-OL

Common Name

English

DELTA-9-TETRAHYDROCANNABINOL

Common Name

English

DELTA-9-THC

Common Name

English

(6aR,10aR)-6a,7,8,10a-Tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo[b,d]pyran-1-ol

Common Name

English

ABBOTT-40566

Code

English

DRONABINOL [ORANGE BOOK]

Common Name

English

J882F

Code

English

Dronabinol [WHO-DD]

Common Name

English

.DELTA.9-THC

Common Name

English

QCD-84924

Code

English

AD313 component dronabinol

Common Name

English

DRONABINOL [VANDF]

Common Name

English

dronabinol [INN]

Common Name

English

TETRAHYDROCANNABINOL, DELTA-9 TRANS

Common Name

English

SP-104

Code

English

.DELTA.-9-TETRAHYDROCANNABINOL

Common Name

English

6H-DIBENZO(B,D)PYRAN-1-OL, 6A,7,8,10A-TETRAHYDRO-6,6,9-TRIMETHYL-3-PENTYL-, (6AR,10AR)-

Common Name

English

SCI-110 component dronabinol

Code

English

DELTA-9-TETRAHYDROCANNABINOL (CANNABIS SATIVA EXTRACT)

Common Name

English

.DELTA.9-TETRAHYDROCANNABINOL

Common Name

English

DRONABINOL [USAN]

Common Name

English

(-)-.DELTA.1-3,4-TRANS-TETRAHYDROCANNABINOL

Common Name

English

AD-313 component dronabinol

Common Name

English

DRONABINOL [HSDB]

Common Name

English

DRONABINOL [MART.]

Common Name

English

DRONABINOL [USP MONOGRAPH]

Common Name

English

NSC-134454

Code

English

TETRAHYDROCANNABINOLS (-)-TRANS-.DELTA.9-FORM [MI]

Common Name

English

6H-DIBENZO(B,D)PYRAN-1-OL, 6A,7,8,10A-TETRAHYDRO-6,6,9-TRIMETHYL-3-PENTYL-, (6AR-TRANS)-

Common Name

English

Classification Tree Code System Code

NDF-RT

N0000008010

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

FDA ORPHAN DRUG

668918

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

DEA NO.

7369

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

NCI_THESAURUS

C267

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

LIVERTOX

NBK548830

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

WHO-ATC

A04AD10

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

FDA ORPHAN DRUG

498215

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

CFR

21 CFR 1308.35

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

FDA ORPHAN DRUG

652218

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

FDA ORPHAN DRUG

54890

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

EU-Orphan Drug

EU/3/16/1621

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

WHO-ATC

N02BG10

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

NDF-RT

N0000175782

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

FDA ORPHAN DRUG

628818

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

WHO-VATC

QA04AD10

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

FDA ORPHAN DRUG

620417

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

FDA ORPHAN DRUG

549616

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

FDA ORPHAN DRUG

734820

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

Code System Code Type Description

ChEMBL

CHEMBL465

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

PRIMARY

RXCUI

10402

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

PRIMARY

RxNorm

DRUG CENTRAL

4109

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

PRIMARY

NSC

134454

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

PRIMARY

IUPHAR

2424

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

PRIMARY

INN

5547

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

PRIMARY

EVMPD

SUB06407MIG

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

PRIMARY

DRUG BANK

DB00470

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

PRIMARY

USAN

T-59

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

PRIMARY

EPA CompTox

DTXSID6021327

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

PRIMARY

MERCK INDEX

m10624

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

PRIMARY

Merck Index

WIKIPEDIA

TETRAHYDROCANNABINOL

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

PRIMARY

CHEBI

66964

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

PRIMARY

LACTMED

Dronabinol

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

PRIMARY

FDA UNII

7J8897W37S

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

PRIMARY

DAILYMED

7J8897W37S

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

PRIMARY

MESH

D013759

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

PRIMARY

NCI_THESAURUS

C867

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

PRIMARY

PUBCHEM

16078

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

PRIMARY

CAS

1972-08-3

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

PRIMARY

SMS_ID

100000090615

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

PRIMARY

HSDB

6471

Created by admin on Fri Dec 15 15:01:16 UTC 2023 , Edited by admin on Fri Dec 15 15:01:16 UTC 2023

PRIMARY

Related Record Type Details


					3318TFY23Q

URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 1A9

METABOLIC ENZYME -> SUBSTRATE

Amount:


					8E4LAA4357

CYTOCHROME P450 2D6

METABOLIC ENZYME -> SUBSTRATE

Interaction Type:

MINOR

Amount:


					M67MK6J9X0

DRONABINOL HEMISUCCINATE

SALT/SOLVATE -> PARENT

Amount:


					NJ1Q2Q7LO5

CANNABINOID RECEPTOR 1

TARGET -> AGONIST

Comments:

Mouse AtT-20 neuroblastoma cells stably transfected with human CB1

Qualification:

EC50

Amount:


					081I12ZA58

CYTOCHROME P450 2C19

METABOLIC ENZYME -> SUBSTRATE

Interaction Type:

MINOR

Amount:


					L9DP834D1P

CYTOCHROME P450 2C9

METABOLIC ENZYME -> SUBSTRATE

Interaction Type:

MAJOR

Amount:


					VK4SQL11C0

CYTOCHROME P450 1A2

METABOLIC ENZYME -> INHIBITOR

Amount:


					0M77ZW789J

URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 2B7

METABOLIC ENZYME -> SUBSTRATE

Amount:


					FTS5RM302N

CANNABIS SATIVA SUBSP. INDICA TOP

PARENT -> ACTIVE CONSTITUENT ALWAYS PRESENT

Comments:

Delta-9-tetrahydrocannabinol class | Euphoriant | Analgesic | Anti-inflammatory | Antioxidant | Antiemetic

Amount:


					SKEU5X23RI

CANNABINOID RECEPTOR 2

TARGET -> AGONIST

Comments:

Mouse AtT-20 neuroblastoma cells stably transfected with human CB2

Qualification:

EC50

Amount:


					PUO0521HZV

CYTOCHROME P450 3A4

METABOLIC ENZYME -> SUBSTRATE

Amount:

Related Record Type Details


					2D48C7R49E

VB-311

PRODRUG -> METABOLITE ACTIVE

Amount:


					GMN7ZX2D3A

VB-309

PRODRUG -> METABOLITE ACTIVE

Amount:


					MHF3368LWJ

VB-312

PRODRUG -> METABOLITE ACTIVE

Amount:


					SH72P2DRU7

VB-310

PRODRUG -> METABOLITE ACTIVE

Amount:


					9VY04N5SLB

11-HYDROXY-.DELTA.9-TETRAHYDROCANNABINOL

METABOLITE ACTIVE -> PARENT

Comments:

Equpotent to DELTA.9-TETRAHYDROCANNABINOL on CB1 receptors

Amount:


					VFD5BFU5ZG

VB-313

PRODRUG -> METABOLITE ACTIVE

Amount:


					4TPC9E4A32

11-NOR-9-CARBOXY-.DELTA.9-TETRAHYDROCANNABINOL

METABOLITE INACTIVE -> PARENT

Qualification:

URINE

Amount:


					671A0K1FQE

8.BETA.-HYDROXY-.DELTA.9-TETRAHYDROCANNABINOL

METABOLITE -> PARENT

Comments:

IN VITRO

Amount:

Related Record Type Details


					4D04V28WF1

EXO-TETRAHYDROCANNABINOL

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					7UYP6MC9GH

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					B49D0HH807

Delta-8-Tetrahydrocannabinol

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:

Related Record Type Details


					7J8897W37S

ACTIVE MOIETY

Amount: