URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 2B7

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 23:26:22 GMT 2025` Edited by `admin` on `Mon Mar 31 23:26:22 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	0M77ZW789J
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 2B7

Common Name

English

3,4-CATECHOL ESTROGEN-SPECIFIC UDPGT

Preferred Name

English

UGT2B7

Common Name

English

UDP-GLUCURONOSYLTRANSFERASE-2B7

Common Name

English

UGT2B9

Common Name

English

UDPGT-2B7

Common Name

English

UDP-GLUCURONOSYLTRANSFERASE-2B9

Common Name

English

Code System Code Type Description

FDA UNII

0M77ZW789J

Created by admin on Mon Mar 31 23:26:22 GMT 2025 , Edited by admin on Mon Mar 31 23:26:22 GMT 2025

PRIMARY

EC (ENZYME CLASS)

EC 2.4.1.17

Created by admin on Mon Mar 31 23:26:22 GMT 2025 , Edited by admin on Mon Mar 31 23:26:22 GMT 2025

PRIMARY

WIKIPEDIA

UGT2B7

Created by admin on Mon Mar 31 23:26:22 GMT 2025 , Edited by admin on Mon Mar 31 23:26:22 GMT 2025

PRIMARY

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_44
N	1_45
N	1_292

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LICOFELONE

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Bempedoic acid

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Empagliflozin

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ROFECOXIB

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					6783M2LV5X

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IC50

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VORINOSTAT

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					36B82AMQ7N

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RIVOCERANIB

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CHLORAMPHENICOL

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					8FG9H9D31J

TAFAMIDIS

SUBSTRATE -> METABOLIC ENZYME

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					12WJ62D047

VERINURAD

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RIVOGLITAZONE

SUBSTRATE -> METABOLIC ENZYME


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DICLOFENAC

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SUBSTRATE -> METABOLIC ENZYME


					S7946O4P76

SESAMIN

SUBSTRATE -> METABOLIC ENZYME

Interaction Type:

MAJOR


					9RL37ZZ665

ORANTINIB

SUBSTRATE -> METABOLIC ENZYME


					4B9XT59T7S

ZIDOVUDINE

SUBSTRATE -> METABOLIC ENZYME


					62XCK0G93T

ORNIDAZOLE

SUBSTRATE -> METABOLIC ENZYME

Interaction Type:

MAJOR


					101V0R1N2E

Febuxostat

SUBSTRATE -> METABOLIC ENZYME


					2U23G6VNUZ

PRADIGASTAT

SUBSTRATE -> METABOLIC ENZYME


					Z5MR2Y1IJJ

ENAVOGLIFLOZIN

SUBSTRATE -> METABOLIC ENZYME

Amount:


					W6HS99O8ZO

VARENICLINE

SUBSTRATE -> METABOLIC ENZYME

Amount:


					7S5I7G3JQL

DEXAMETHASONE

INDUCER -> METABOLIC ENZYME


					5G7AKV2MKP

PONESIMOD

SUBSTRATE -> METABOLIC ENZYME

Amount:


					48I5LU4ZWD

MECLOFENAMIC ACID

INHIBITOR -> METABOLIC ENZYME

Interaction Type:

POTENT


					8VZV102JFY

FLUCONAZOLE

METABOLIC ENZYME -> INHIBITOR

Interaction Type:

POTENT


					R3ZGC15A9A

LERSIVIRINE

SUBSTRATE -> METABOLIC ENZYME

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					637E494O0Z

LORCASERIN

SUBSTRATE -> METABOLIC ENZYME

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NEBICAPONE

SUBSTRATE -> METABOLIC ENZYME

Interaction Type:

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CLOFIBRIC ACID

SUBSTRATE -> METABOLIC ENZYME


					VD2YSN1AFD

OLODATEROL

SUBSTRATE -> METABOLIC ENZYME


					614OI1Z5WI

VALPROIC ACID

SUBSTRATE -> METABOLIC ENZYME


					ER29L26N1X

COBIMETINIB

SUBSTRATE -> METABOLIC ENZYME


					144O8QL0L1

DICLOFENAC

SUBSTRATE -> METABOLIC ENZYME

Interaction Type:

POTENT


					2PEX5N7DQ4

FEVIPIPRANT

SUBSTRATE -> METABOLIC ENZYME

Amount:


					YQE403BP4D

PHENOBARBITAL

INDUCER -> METABOLIC ENZYME


					7J8897W37S

DRONABINOL

SUBSTRATE -> METABOLIC ENZYME

Amount:


					7LKK855W8I

Letrozole

SUBSTRATE -> METABOLIC ENZYME

Amount:


					A74586SNO7

CLOPIDOGREL

SUBSTRATE -> METABOLIC ENZYME

Comments:

UGT2B7 is the main enzyme involved in clopidogrel carboxylic acid glucuronidation in the liver

Amount:


					367589PJ2C

MEFENAMIC ACID

INHIBITOR -> METABOLIC ENZYME


					KG60484QX9

OMEPRAZOLE

INDUCER -> METABOLIC ENZYME


					P85X70RZWS

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SUBSTRATE -> METABOLIC ENZYME

Interaction Type:

MAJOR

Amount:


					S39XZ5QV8Y

BREXANOLONE

SUBSTRATE -> METABOLIC ENZYME


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SUBSTRATE -> METABOLIC ENZYME


					G70A8514T8

FALECALCITRIOL

SUBSTRATE -> METABOLIC ENZYME

Interaction Type:

MINOR

Amount:


					S798V6YJRP

EDARAVONE

SUBSTRATE -> METABOLIC ENZYME


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SUBSTRATE -> METABOLIC ENZYME

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER AVERAGE(CALCULATED)	CHEMICAL