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Details

Stereochemistry ABSOLUTE
Molecular Formula C16H16ClNO2S
Molecular Weight 321.822
Optical Activity ( + )
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CLOPIDOGREL

SMILES

COC(=O)[C@@H](N1CCC2=C(C1)C=CS2)C3=CC=CC=C3Cl

InChI

InChIKey=GKTWGGQPFAXNFI-HNNXBMFYSA-N
InChI=1S/C16H16ClNO2S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14/h2-5,7,9,15H,6,8,10H2,1H3/t15-/m0/s1

HIDE SMILES / InChI
Molecular Formula C16H16ClNO2S
Molecular Weight 321.822
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Sat Dec 16 17:42:51 UTC 2023
Edited
by admin
on Sat Dec 16 17:42:51 UTC 2023
Record UNII
A74586SNO7
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CLOPIDOGREL
EMA EPAR   HSDB   INN   MI   VANDF   WHO-DD  
INN  
Official Name English
clopidogrel [INN]
Common Name English
(S)-METHYL .ALPHA.-(4,5,6,7-TETRAHYDROTHIENO(3,2-C)PYRIDIN-5-YL)-.ALPHA.-(O-CHLOROPHENYL)ACETATE
Common Name English
SR-25990
Code English
CLOPIDOGREL [HSDB]
Common Name English
NSC-758613
Code English
THROMBO
Common Name English
(+)-(S)-CLOPIDOGREL
Common Name English
SR 25990
Code English
CLOPIDOGREL [VANDF]
Common Name English
R 130964
Code English
METHYL 2-(2-CHLOROPHENYL)-2-(4,5,6,7-TETRAHYDROTHIENO(3,2-C)PYRIDIN-5-YL)ACETATE
Systematic Name English
ZYLLT
Common Name English
CLOPIDOGREL [EMA EPAR]
Common Name English
CLOPIDOGREL [MI]
Common Name English
R-130964
Code English
Clopidogrel [WHO-DD]
Common Name English
Classification Tree Code System Code
NDF-RT N0000008832
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
WHO-VATC QB01AC04
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
WHO-ATC B01AC04
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
NCI_THESAURUS C80483
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
EMA ASSESSMENT REPORTS CLOPIDOGREL ACINO (AUTHORIZED:ACUTE CORONARY SYNDROME)
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
NDF-RT N0000008832
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
NDF-RT N0000182142
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
NDF-RT N0000175578
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
LIVERTOX NBK547946
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
EMA ASSESSMENT REPORTS CLOPIDOGREL ACINO (AUTHORIZED: MYOCARDIAL INFARCTION)
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
Code System Code Type Description
ChEMBL
CHEMBL1771
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
PRIMARY
MESH
C055162
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
PRIMARY
DRUG BANK
DB00758
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
PRIMARY
SMS_ID
100000091166
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
PRIMARY
HSDB
7430
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
PRIMARY
MERCK INDEX
m3655
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
PRIMARY Merck Index
CAS
113665-84-2
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
PRIMARY
WIKIPEDIA
CLOPIDOGREL
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
PRIMARY
INN
5908
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
PRIMARY
NSC
758613
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
PRIMARY
NDF-RT
N0000182143
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
PRIMARY P2Y12 Receptor Antagonists [MoA]
IUPHAR
7150
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
PRIMARY
EVMPD
SUB13395MIG
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
PRIMARY
EPA CompTox
DTXSID6022848
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
PRIMARY
DRUG CENTRAL
708
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
PRIMARY
LACTMED
Clopidogrel
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
PRIMARY
CHEBI
37941
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
PRIMARY
DAILYMED
A74586SNO7
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
PRIMARY
FDA UNII
A74586SNO7
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
PRIMARY
RXCUI
32968
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
PRIMARY RxNorm
NCI_THESAURUS
C61686
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
PRIMARY
PUBCHEM
60606
Created by admin on Sat Dec 16 17:42:55 UTC 2023 , Edited by admin on Sat Dec 16 17:42:55 UTC 2023
PRIMARY
Related Record Type Details
URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 2B17
METABOLIC ENZYME -> SUBSTRATE
UGT2B17 has a major role in the intestinal metabolism of clopidogrel.
Structure of CLOPIDOGREL BISULFATE
SALT/SOLVATE -> PARENT
Structure of CLOPIDOGREL 5-SULFOSALICYLATE
SALT/SOLVATE -> PARENT
Structure of CLOPIDOGREL HYDROBROMIDE
SALT/SOLVATE -> PARENT
Structure of Clopidogrel napadisilate monohydrate
SALT/SOLVATE -> PARENT
P2Y PURINOCEPTOR 12
TARGET -> INHIBITOR
Structure of CLOPIDOGREL HYDROBROMIDE MONOHYDRATE
SALT/SOLVATE -> PARENT
LIVER CARBOXYLESTERASE 1
METABOLIC ENZYME -> SUBSTRATE
Structure of CLOPIDOGREL CAMSYLATE
SALT/SOLVATE -> PARENT
Structure of CLOPIDOGREL BESYLATE
SALT/SOLVATE -> PARENT
Structure of CLOPIDOGREL HYDROCHLORIDE
SALT/SOLVATE -> PARENT
URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 2B7
METABOLIC ENZYME -> SUBSTRATE
UGT2B7 is the main enzyme involved in clopidogrel carboxylic acid glucuronidation in the liver
Structure of CLOPIDOGREL NAPADISILATE
SALT/SOLVATE -> PARENT
CYTOCHROME P450 3A4
METABOLIC ENZYME -> SUBSTRATE
Related Record Type Details
Structure of CLOPIDOGREL ACYL-.BETA.-D-GLUCURONIDE
METABOLITE -> PARENT
Structure of 3-(CARBOXYMETHYLENE)-.ALPHA.-(2-CHLOROPHENYL)-4-MERCAPTO-1-PIPERIDINEACETIC ACID 1-METHYL ESTER, (.ALPHA.S,3Z,4S)-
METABOLITE INACTIVE -> PARENT
IN-VITRO
Scientific Literature
Structure of 3-(CARBOXYMETHYLENE)-.ALPHA.-(2-CHLOROPHENYL)-4-MERCAPTO-1-PIPERIDINEACETIC ACID 1-METHYL ESTER, (.ALPHA.S,3E,4R)-
METABOLITE ACTIVE -> PARENT
Structure of 3-(CARBOXYMETHYLENE)-.ALPHA.-(2-CHLOROPHENYL)-4-MERCAPTO-1-PIPERIDINEACETIC ACID 1-METHYL ESTER, (.ALPHA.S,3E,4S)-
METABOLITE INACTIVE -> PARENT
Structure of 3-(CARBOXYMETHYLENE)-.ALPHA.-(2-CHLOROPHENYL)-4-MERCAPTO-1-PIPERIDINEACETIC ACID .ALPHA.-METHYL ESTER, (.ALPHA.S,3Z,4R)-
METABOLITE ACTIVE -> PRODRUG
IN-VIVO
PLASMA
Name Property Type Amount Referenced Substance Defining Parameters References
ORAL BIOAVAILABILITY PHARMACOKINETIC
Tmax PHARMACOKINETIC
Biological Half-life PHARMACOKINETIC THIOL DERIVATIVE
PHARMACOKINETIC
NIH
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