P2Y PURINOCEPTOR 12

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 18:32:35 GMT 2025` Edited by `admin` on `Tue Apr 01 18:32:35 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	O0QUP6NQ1H
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

P2Y PURINOCEPTOR 12

Common Name

English

ADP-GLUCOSE RECEPTOR

Preferred Name

English

P2Y12

Common Name

English

SP1999

Common Name

English

ADPG-R

Common Name

English

P2Y(CYC)

Common Name

English

HORK3

Common Name

English

P2Y(AC)

Common Name

English

P2Y12 PLATELET ADP RECEPTOR

Common Name

English

Code System Code Type Description

UNIPROT

Q9H244

Created by admin on Tue Apr 01 18:32:35 GMT 2025 , Edited by admin on Tue Apr 01 18:32:35 GMT 2025

PRIMARY

FDA UNII

O0QUP6NQ1H

Created by admin on Tue Apr 01 18:32:35 GMT 2025 , Edited by admin on Tue Apr 01 18:32:35 GMT 2025

PRIMARY

PHAROS

Q9H244

Created by admin on Tue Apr 01 18:32:35 GMT 2025 , Edited by admin on Tue Apr 01 18:32:35 GMT 2025

PRIMARY

From	To
1_17	1_270
1_97	1_175

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_6
N	1_13

Related Record Type Details


					RUM6K67ESG

Treprostinil

AGONIST -> TARGET

Amount:


					915Y8E749J

ELINOGREL

INHIBITOR -> TARGET

Amount:


					GLH0314RVC

TICAGRELOR

INHIBITOR -> TARGET

Amount:


					KDT372MQ8M

AZD-1283

INHIBITOR -> TARGET

Amount:


					6AQ1Y404U7

CANGRELOR

INHIBITOR -> TARGET

Amount:


					4T2K9E4TEH

3-(CARBOXYMETHYLENE)-.ALPHA.-(2-CHLOROPHENYL)-4-MERCAPTO-1-PIPERIDINEACETIC ACID .ALPHA.-METHYL ESTER, (.ALPHA.S,3Z,4R)-

INHIBITOR -> TARGET

Interaction Type:

IN-VITRO

Qualification:

IC50


					34K66TBT99

PRASUGREL

INHIBITOR -> TARGET

Amount:


					Q6C8TY6SW1

REGRELOR

INHIBITOR -> TARGET

Amount:


					61D2G4IYVH

ADENOSINE DIPHOSPHATE

AGONIST -> TARGET

Comments:

Leads to platelet activation

Amount:


					A74586SNO7

CLOPIDOGREL

INHIBITOR -> TARGET

Amount:


					6DPK7O4PR7

SELATOGREL

INHIBITOR -> TARGET

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_55] [1_57]				DEXFOSFOSERINE	VI4F0K069V

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT	CHEMICAL