Inlecitug

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 21:00:21 GMT 2025` Edited by `admin` on `Wed Apr 02 21:00:21 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1\|KAPPA
Sequence Origin	MOUSE CHIMERIC
Sequence Type	COMPLETE
Record UNII	FA5YAU8H6R
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Inlecitug

Official Name

English

H-gamma1 heavy chain chimeric (1-447) [VH (Mus musculus IGHV14-4*02 (91.8%) -(IGHD) -IGHJ4*01 (91.7%) S123>T (112), CDR-IMGT [8.8.10] (26-33.51-58.97-106)) (1-117) -Homo sapiens IGHG1*01 (100%) G1m17,1 CH1 K120, CH3 D12, L14 (CH1 K120 (214) (118-215), hi

Preferred Name

English

immunoglobulin G1-kappa, anti-[Homo sapiens KDR (kinase insert domain receptor, vascular endothelial growth factor receptor 2, VEGFR2, VEGF-R2, FLK1, CD309)], chimeric monoclonal antibody

Common Name

English

Immunoglobulin G1, anti-(human vascular endothelial growth factor receptor 2) (human monoclonal GenSci043 ?1-chain), disulfide with human monoclonal GenSci043 ?-chain, dimer

Common Name

English

inlecitug [INN]

Common Name

English

Code System Code Type Description

CAS

2997627-68-4

Created by admin on Wed Apr 02 21:00:21 GMT 2025 , Edited by admin on Wed Apr 02 21:00:21 GMT 2025

PRIMARY

FDA UNII

FA5YAU8H6R

Created by admin on Wed Apr 02 21:00:21 GMT 2025 , Edited by admin on Wed Apr 02 21:00:21 GMT 2025

PRIMARY

INN

13399

Created by admin on Wed Apr 02 21:00:21 GMT 2025 , Edited by admin on Wed Apr 02 21:00:21 GMT 2025

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_144	2_200
2_220	4_213
2_261	2_321
1_144	1_200
2_367	2_425
3_23	3_87
3_133	3_193
4_23	4_87
4_133	4_193
1_220	3_213
1_226	2_226
1_229	2_229
1_261	1_321
1_367	1_425

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_297
N	2_297

Related Record Type Details


					798536Z7S0

VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2

TARGET->LIGAND

Amount:

Related Record Type Details


					FA5YAU8H6R

Inlecitug

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_447] [2_447]	C-TERMINUS	K		LYSINE	K3Z4F929H6
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]	N-TERMINUS	Q		PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL