Ruzaltatug

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 18:07:00 GMT 2025` Edited by `admin` on `Wed Apr 02 18:07:00 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1\|KAPPA
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	GS38RAB375
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Ruzaltatug

Official Name

English

H-gamma1 heavy chain Homo sapiens (1-447) [VH (Homo sapiens IGHV3-9*01 (97.0%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.10] (26-33.51-58.97-106)) (1-117) -Homo sapiens IGHG1*01 (100%) G1m17,1 CH1 K120, CH3 D12, L14 (CH1 K120 (214) (118-215), hinge 1-15 (

Preferred Name

English

Immunoglobulin G1, anti-(human epidermal growth factor receptor HER3) (human monoclonal SHR-2008 ?1-chain), disulfide with human monoclonal SHR-2008 ?-chain, dimer

Common Name

English

ruzaltatug [INN]

Common Name

English

immunoglobulin G1-kappa, anti-[Homo sapiens ERBB3 (receptor tyrosine-protein kinase erbB-3, HER3)], Homo sapiens monoclonal antibody (ruzaltatug)

Common Name

English

Code System Code Type Description

FDA UNII

GS38RAB375

Created by admin on Wed Apr 02 18:07:00 GMT 2025 , Edited by admin on Wed Apr 02 18:07:00 GMT 2025

PRIMARY

CAS

2981438-63-3

Created by admin on Wed Apr 02 18:07:00 GMT 2025 , Edited by admin on Wed Apr 02 18:07:00 GMT 2025

PRIMARY

INN

13336

Created by admin on Wed Apr 02 18:07:00 GMT 2025 , Edited by admin on Wed Apr 02 18:07:00 GMT 2025

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_144	2_200
2_220	4_215
2_261	2_321
1_144	1_200
2_367	2_425
3_23	3_88
3_135	3_195
4_23	4_88
4_135	4_195
1_220	3_215
1_226	2_226
1_229	2_229
1_261	1_321
1_367	1_425