LERIGLITAZONE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C19H20N2O4S
Molecular Weight	372.438
Optical Activity	( + / - )
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of LERIGLITAZONE

Structure Search

SMILES

CC(O)C1=CC=C(CCOC2=CC=C(CC3SC(=O)NC3=O)C=C2)N=C1

InChI

InChIKey=OXVFDZYQLGRLCD-UHFFFAOYSA-N

InChI=1S/C19H20N2O4S/c1-12(22)14-4-5-15(20-11-14)8-9-25-16-6-2-13(3-7-16)10-17-18(23)21-19(24)26-17/h2-7,11-12,17,22H,8-10H2,1H3,(H,21,23,24)

HIDE SMILES / InChI

Molecular Formula	C19H20N2O4S
Molecular Weight	372.438
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:38:10 UTC 2023` Edited by `admin` on `Fri Dec 15 16:38:10 UTC 2023`
Record UNII	K824X25AYA
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

LERIGLITAZONE

Official Name

English

leriglitazone [INN]

Common Name

English

LERIGLITAZONE [USAN]

Common Name

English

HYDROXYPIOGLITAZONE

Common Name

English

2,4-THIAZOLIDINEDIONE, 5-((4-(2-(5-(1-HYDROXYETHYL)-2-PYRIDINYL)ETHOXY)PHENYL)METHYL)-

Systematic Name

English

MIN-102

Code

English

ALL-AMBO-5-((4-(2-(5-(1-HYDROXYETHYL)PYRIDIN-2-YL)ETHOXY)PHENYL)METHYL)-1,3-THIAZOLE-2,4(3H,5H)-DIONE

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

552716

Created by admin on Fri Dec 15 16:38:10 UTC 2023 , Edited by admin on Fri Dec 15 16:38:10 UTC 2023

FDA ORPHAN DRUG

700919

Created by admin on Fri Dec 15 16:38:10 UTC 2023 , Edited by admin on Fri Dec 15 16:38:10 UTC 2023

Code System Code Type Description

EU-Orphan Drug

EU/3/16/1770(POSITIVE)

Created by admin on Fri Dec 15 16:38:10 UTC 2023 , Edited by admin on Fri Dec 15 16:38:10 UTC 2023

PRIMARY

Treatment of adrenoleukodystrophy 18/11/2016 Positive

CAS

146062-44-4

Created by admin on Fri Dec 15 16:38:10 UTC 2023 , Edited by admin on Fri Dec 15 16:38:10 UTC 2023

PRIMARY

EVMPD

SUB196367

Created by admin on Fri Dec 15 16:38:10 UTC 2023 , Edited by admin on Fri Dec 15 16:38:10 UTC 2023

PRIMARY

PUBCHEM

4147757

Created by admin on Fri Dec 15 16:38:10 UTC 2023 , Edited by admin on Fri Dec 15 16:38:10 UTC 2023

PRIMARY

INN

10868

Created by admin on Fri Dec 15 16:38:10 UTC 2023 , Edited by admin on Fri Dec 15 16:38:10 UTC 2023

PRIMARY

NCI_THESAURUS

C170108

Created by admin on Fri Dec 15 16:38:10 UTC 2023 , Edited by admin on Fri Dec 15 16:38:10 UTC 2023

PRIMARY

EPA CompTox

DTXSID30399914

Created by admin on Fri Dec 15 16:38:10 UTC 2023 , Edited by admin on Fri Dec 15 16:38:10 UTC 2023

PRIMARY

USAN

GH-65

Created by admin on Fri Dec 15 16:38:10 UTC 2023 , Edited by admin on Fri Dec 15 16:38:10 UTC 2023

PRIMARY

SMS_ID

100000182339

Created by admin on Fri Dec 15 16:38:10 UTC 2023 , Edited by admin on Fri Dec 15 16:38:10 UTC 2023

PRIMARY

DRUG BANK

DB15021

Created by admin on Fri Dec 15 16:38:10 UTC 2023 , Edited by admin on Fri Dec 15 16:38:10 UTC 2023

PRIMARY

FDA UNII

K824X25AYA

Created by admin on Fri Dec 15 16:38:10 UTC 2023 , Edited by admin on Fri Dec 15 16:38:10 UTC 2023

PRIMARY

Related Record Type Details


					AL17N8ZSWL

PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA

TARGET -> AGONIST


					WN9K42SAM6

LERIGLITAZONE HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Related Record Type Details


					X4OV71U42S

PARENT -> METABOLITE ACTIVE

Related Record Type Details


					K824X25AYA

ACTIVE MOIETY