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Details

Stereochemistry RACEMIC
Molecular Formula C19H20N2O3S
Molecular Weight 356.439
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PIOGLITAZONE

SMILES

CCC1=CC=C(CCOC2=CC=C(CC3SC(=O)NC3=O)C=C2)N=C1

InChI

InChIKey=HYAFETHFCAUJAY-UHFFFAOYSA-N
InChI=1S/C19H20N2O3S/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23)

HIDE SMILES / InChI
Molecular Formula C19H20N2O3S
Molecular Weight 356.439
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Sat Dec 16 16:18:57 UTC 2023
Edited
by admin
on Sat Dec 16 16:18:57 UTC 2023
Record UNII
X4OV71U42S
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PIOGLITAZONE
EMA EPAR   HSDB   INN   MI   VANDF   WHO-DD  
INN  
Official Name English
5-(4-(2-(5-ETHYLPYRIDIN-2-YL)ETHOXY)BENZYL)THIAZOLIDINE-2,4-DIONE
Systematic Name English
PIOGLITAZONE [MI]
Common Name English
pioglitazone [INN]
Common Name English
ZACTOS
Brand Name English
5-((4-(2-(5-ETHYL-2-PYRIDINYL)ETHOXY)PHENYL)METHYL)-2,4-THIAZOLIDINEDIONE
Systematic Name English
AD-4833
Code English
PIOGLITAZONE [EMA EPAR]
Common Name English
PIOGLITAZONE [VANDF]
Common Name English
(RS)-5-(4-(2-(5-ETHYLPYRIDIN-2-YL)ETHOXY)BENZYL)THIAZOLIDINE-2,4-DIONE
Systematic Name English
2,4-THIAZOLIDINEDIONE, 5-((4-(2-(5-ETHYL-2-PYRIDINYL)ETHOXY)PHENYL)METHYL)-, (±)-
Systematic Name English
PIOGLITAZONE [HSDB]
Common Name English
2,4-THIAZOLIDINEDIONE, 5-((4-(2-(5-ETHYL-2-PYRIDINYL)ETHOXY)PHENYL)METHYL)-
Systematic Name English
PIOGLITAZONE [IARC]
Common Name English
GLUSTIN
Brand Name English
Pioglitazone [WHO-DD]
Common Name English
U-72107
Code English
(±)-5-(P-(2-(5-ETHYL-2-PYRIDYL)ETHOXY)BENZYL)-2,4-THIAZOLIDINEDIONE
Common Name English
5-(4-(2-(5-ETHYL-2-PYRIDYL)ETHOXY)BENZYL)THIAZOLIDINE-2,4-DIONE
Systematic Name English
Classification Tree Code System Code
NDF-RT N0000170118
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
WHO-VATC QA10BD09
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
FDA ORPHAN DRUG 583017
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
NDF-RT N0000170119
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
LIVERTOX NBK548327
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
WHO-ATC A10BD05
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
WHO-VATC QA10BD06
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
NDF-RT N0000180186
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
EU-Orphan Drug EU/3/14/1245
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
NCI_THESAURUS C98241
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
NDF-RT N0000170118
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
NDF-RT N0000175374
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
NDF-RT N0000170119
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
WHO-ATC A10BD12
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
NDF-RT N0000011272
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
NDF-RT N0000011272
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
WHO-ATC A10BD09
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
NDF-RT N0000180190
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
WHO-ATC A10BG03
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
WHO-VATC QA10BG03
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
NDF-RT N0000011272
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
WHO-VATC QA10BD05
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
WHO-ATC A10BD06
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
WHO-VATC QA10BD12
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
NDF-RT N0000175596
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
Code System Code Type Description
DRUG CENTRAL
2179
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
PRIMARY
NCI_THESAURUS
C71633
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
PRIMARY
DAILYMED
X4OV71U42S
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
PRIMARY
MERCK INDEX
m8835
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
PRIMARY Merck Index
PUBCHEM
4829
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
PRIMARY
CAS
111025-46-8
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
PRIMARY
INN
6343
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
PRIMARY
CAS
105355-27-9
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
SUPERSEDED
SMS_ID
100000085494
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
PRIMARY
ChEMBL
CHEMBL595
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
PRIMARY
WIKIPEDIA
PIOGLITAZONE
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
PRIMARY
EPA CompTox
DTXSID3037129
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
PRIMARY
CHEBI
8228
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
PRIMARY
EVMPD
SUB09857MIG
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
PRIMARY
IUPHAR
2694
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
PRIMARY
FDA UNII
X4OV71U42S
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
PRIMARY
RXCUI
33738
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
PRIMARY RxNorm
HSDB
7322
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
PRIMARY
CAS
198077-89-3
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
SUPERSEDED
LACTMED
Pioglitazone
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
PRIMARY
DRUG BANK
DB01132
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
PRIMARY
MESH
C060836
Created by admin on Sat Dec 16 16:18:58 UTC 2023 , Edited by admin on Sat Dec 16 16:18:58 UTC 2023
PRIMARY
Related Record Type Details
Structure of PIOGLITAZONE HYDROCHLORIDE
SALT/SOLVATE -> PARENT
BSEP
TRANSPORTER -> INHIBITOR
IC50
PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA
TARGET -> AGONIST
PLASMA PROTEIN FRACTION (HUMAN)
BINDER->LIGAND
BINDING
OCT-1
TRANSPORTER -> INHIBITOR
Related Record Type Details
Structure of 3-PYRIDINECARBOXYLIC ACID, 6-(2-(4-((2,4-DIOXO-5-THIAZOLIDINYL)METHYL)PHENOXY)ETHYL)-
METABOLITE INACTIVE -> PARENT
Structure of 3-PYRIDINEACETIC ACID, 6-(2-(4-((2,4-DIOXO-5-THIAZOLIDINYL)METHYL)PHENOXY)ETHYL)-
METABOLITE INACTIVE -> PARENT
Structure of KETOPIOGLITAZONE
METABOLITE ACTIVE -> PARENT
Structure of 2-HYDROXYPIOGLITAZONE
METABOLITE ACTIVE -> PARENT
Structure of LERIGLITAZONE
METABOLITE ACTIVE -> PARENT
Structure of 5-((4-(2-HYDROXY-2-(5-(1-HYDROXYETHYL)-2-PYRIDINYL)ETHOXY)PHENYL)METHYL)-2,4-THIAZOLIDINEDIONE
METABOLITE INACTIVE -> PARENT
Structure of U-90441
METABOLITE INACTIVE -> PARENT
Related Record Type Details
Structure of PIOGLITAZONE
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Volume of Distribution PHARMACOKINETIC
Biological Half-life PHARMACOKINETIC
NIH
NCATS
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