CGP-52421

Details

Stereochemistry	EPIMERIC
Molecular Formula	C35H30N4O5
Molecular Weight	586.6365
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 5
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)N3C4=C(C=CC=C4)C5=C3C6=C(C7=C(C=CC=C7)N26)C8=C5C(O)NC8=O)N(C)C(=O)C9=CC=CC=C9

InChI

InChIKey=ZZSBPGIGIUFJRA-YMZPHHGTSA-N

InChI=1S/C35H30N4O5/c1-35-31(43-3)23(37(2)34(42)18-11-5-4-6-12-18)17-24(44-35)38-21-15-9-7-13-19(21)25-27-28(33(41)36-32(27)40)26-20-14-8-10-16-22(20)39(35)30(26)29(25)38/h4-16,23-24,31,33,41H,17H2,1-3H3,(H,36,40)/t23-,24-,31-,33?,35+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C35H30N4O5
Molecular Weight	586.6365
Charge	0
Count

Stereochemistry	EPIMERIC
Additional Stereochemistry	No
Defined Stereocenters	4 / 5
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Tue Apr 01 21:04:40 GMT 2025` Edited by `admin` on `Tue Apr 01 21:04:40 GMT 2025`
Record UNII	D9B1PJ9MWX
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

7-HYDROXY-PKC412

Preferred Name

English

CGP-52421

Code

English

CGP52421

Code

English

BENZAMIDE, N-(2,3,10,11,12,13-HEXAHYDRO-3-HYDROXY-10-METHOXY-9-METHYL-1-OXO-9,13-EPOXY-1H,9H-DIINDOLO(1,2,3-GH:3',2',1'-LM)PYRROLO(3,4-J)(1,7)BENZODIAZONIN-11-YL)-N-METHYL-

Systematic Name

English

N-(2,3,10,11,12,13-HEXAHYDRO-3-HYDROXY-10-METHOXY-9-METHYL-1-OXO-9,13-EPOXY-1H,9H-DIINDOLO(1,2,3-GH:3',2',1'-LM)PYRROLO(3,4-J)(1,7)BENZODIAZONIN-11-YL)-N-METHYLBENZAMIDE

Systematic Name

English

Code System Code Type Description

CAS

179237-49-1

Created by admin on Tue Apr 01 21:04:40 GMT 2025 , Edited by admin on Tue Apr 01 21:04:40 GMT 2025

PRIMARY

FDA UNII

D9B1PJ9MWX

Created by admin on Tue Apr 01 21:04:40 GMT 2025 , Edited by admin on Tue Apr 01 21:04:40 GMT 2025

PRIMARY

PUBCHEM

137552093

Created by admin on Tue Apr 01 21:04:40 GMT 2025 , Edited by admin on Tue Apr 01 21:04:40 GMT 2025

PRIMARY

Related Record Type Details


					JS20X60RRY

TYROSINE-PROTEIN KINASE SYK

TARGET -> INHIBITOR

Interaction Type:

INHIBITOR

Qualification:

IC50

Amount:


					EXBA2DRFUB

PLATELET-DERIVED GROWTH FACTOR RECEPTOR ALPHA

TARGET -> INHIBITOR

Interaction Type:

INHIBITOR

Qualification:

IC50

Amount:


					DNV5PYD2QS

RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 D835Y

TARGET -> INHIBITOR


					2VXO9I489U

MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR

TARGET -> INHIBITOR

Interaction Type:

INHIBITOR

Qualification:

IC50

Amount:


					4796L35A70

RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3

TARGET -> INHIBITOR

Interaction Type:

INHIBITOR

Qualification:

IC50

Amount:

Related Record Type Details


					ID912S5VON

MIDOSTAURIN

PARENT -> METABOLITE LESS ACTIVE