DNA TOPOISOMERASE 1

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 19:27:19 GMT 2025` Edited by `admin` on `Tue Apr 01 19:27:19 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	FUV56ZH0GB
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DNA TOPOISOMERASE 1

Common Name

English

DNA TOPOISOMERASE I

Preferred Name

English

TOP1

Common Name

English

Code System Code Type Description

UNIPROT

P11387

Created by admin on Tue Apr 01 19:27:19 GMT 2025 , Edited by admin on Tue Apr 01 19:27:19 GMT 2025

PRIMARY

FDA UNII

FUV56ZH0GB

Created by admin on Tue Apr 01 19:27:19 GMT 2025 , Edited by admin on Tue Apr 01 19:27:19 GMT 2025

PRIMARY

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Structural Modifications

Modification Type	Location Site	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_505]	DEXFOSFOSERINE	VI4F0K069V
AMINO ACID SUBSTITUTION	[1_171] [1_279]	N6-ACETYLLYSINE	470AD5VY1X
AMINO ACID SUBSTITUTION	[1_1]	N-ACETYLSERINE	W98518XGZ3
AMINO ACID SUBSTITUTION	[1_9] [1_56] [1_111]	DEXFOSFOSERINE	VI4F0K069V

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL