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Details

Stereochemistry ACHIRAL
Molecular Formula C20H23N
Molecular Weight 277.4033
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of AMITRIPTYLINE

SMILES

CN(C)CCC=C1C2=C(CCC3=C1C=CC=C3)C=CC=C2

InChI

InChIKey=KRMDCWKBEZIMAB-UHFFFAOYSA-N
InChI=1S/C20H23N/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20/h3-6,8-12H,7,13-15H2,1-2H3

HIDE SMILES / InChI
Molecular Formula C20H23N
Molecular Weight 277.4033
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
123738
Substance Class Chemical
Created
by admin
on Sat Dec 16 18:01:32 UTC 2023
Edited
by admin
on Sat Dec 16 18:01:32 UTC 2023
Record UNII
1806D8D52K
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AMITRIPTYLINE
INN   MART.   MI   VANDF   WHO-DD  
INN  
Official Name English
1-PROPANAMINE, 3-(10,11-DIHYDRO-5H-DIBENZO(A,D)CYCLOHEPTEN-5-YLIDENE)-N,N-DIMETHYL-
Systematic Name English
LAROXYL
Brand Name English
3-(10,11-DIHYDRO-5H-DIBENZO(A,D)CYCLOHEPTEN-5-YLIDENE)-N,N-DIMETHYL-1-PROPANAMINE
Systematic Name English
AMITRIPTYLINE [USP IMPURITY]
Common Name English
AMITRIPTYLINE [MI]
Common Name English
AMITRIPTYLINE [VANDF]
Common Name English
amitriptyline [INN]
Common Name English
NORTRIPTYLINE HYDROCHLORIDE IMPURITY F [EP IMPURITY]
Common Name English
Amitriptyline [WHO-DD]
Common Name English
AMITRIPTYLINE [MART.]
Common Name English
SEROTEN
Common Name English
PROHEPTADIENE
Common Name English
TRIPTANOL
Common Name English
DAMITRIPTYLINE
Common Name English
FLAVYL
Common Name English
Classification Tree Code System Code
WHO-ATC N06CA01
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 24.2.1
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
FDA ORPHAN DRUG 288809
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
WHO-VATC QN06AA09
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
LIVERTOX NBK548410
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
NDF-RT N0000175752
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
FDA ORPHAN DRUG 739620
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 8.4
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
NCI_THESAURUS C94727
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
WHO-VATC QN06CA01
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
WHO-ATC N06AA09
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
Code System Code Type Description
MESH
D000639
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
PRIMARY
LACTMED
Amitriptyline
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
PRIMARY
SMS_ID
100000092029
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
PRIMARY
WIKIPEDIA
AMITRIPTYLINE
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
PRIMARY
HSDB
3007
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
PRIMARY
INN
976
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
PRIMARY
PUBCHEM
2160
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
PRIMARY
IUPHAR
200
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
PRIMARY
CAS
50-48-6
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
PRIMARY
EVMPD
SUB05462MIG
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
PRIMARY
CHEBI
2666
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
PRIMARY
MERCK INDEX
m1753
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
PRIMARY Merck Index
NCI_THESAURUS
C62005
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
PRIMARY
RXCUI
704
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
PRIMARY RxNorm
ChEMBL
CHEMBL629
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
PRIMARY
FDA UNII
1806D8D52K
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
PRIMARY
EPA CompTox
DTXSID7022594
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
PRIMARY
DRUG BANK
DB00321
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
PRIMARY
DRUG CENTRAL
180
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
PRIMARY
DAILYMED
1806D8D52K
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
PRIMARY
ECHA (EC/EINECS)
200-041-6
Created by admin on Sat Dec 16 18:01:35 UTC 2023 , Edited by admin on Sat Dec 16 18:01:35 UTC 2023
PRIMARY
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Related Record Type Details
Structure of AMITRIPTYLINE
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Volume of Distribution PHARMACOKINETIC
Volume of Distribution PHARMACOKINETIC
MAXIMUM TOLERATED DOSE TOXICITY DEPRESSION, INPATIENTS: 300 MG/DAY

Route of Elimination PHARMACOKINETIC
Biological Half-life PHARMACOKINETIC
NIH
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