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Details

Stereochemistry ACHIRAL
Molecular Formula C28H27N7O
Molecular Weight 477.5603
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CEP-11981

SMILES

CC(C)CN1C2=C(C=C(NC3=NC=CC=N3)C=C2)C4=C1C5=C(C6=CN(C)N=C6CC5)C7=C4CNC7=O

InChI

InChIKey=AEULIVPVIDOLIN-UHFFFAOYSA-N
InChI=1S/C28H27N7O/c1-15(2)13-35-22-8-5-16(32-28-29-9-4-10-30-28)11-18(22)24-19-12-31-27(36)25(19)23-17(26(24)35)6-7-21-20(23)14-34(3)33-21/h4-5,8-11,14-15H,6-7,12-13H2,1-3H3,(H,31,36)(H,29,30,32)

HIDE SMILES / InChI
Molecular Formula C28H27N7O
Molecular Weight 477.5603
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
123738
Substance Class Chemical
Created
by admin
on Sat Dec 16 01:57:25 UTC 2023
Edited
by admin
on Sat Dec 16 01:57:25 UTC 2023
Record UNII
J8AY0Z4CBP
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CEP-11981
Code English
BOL-303213X
Code English
CEP11981
Code English
4H-INDAZOLO(5,4-A)PYRROLO(3,4-C)CARBAZOL-4-ONE, 2,5,6,11,12,13-HEXAHYDRO-2-METHYL-11-(2-METHYLPROPYL)-8-(2-PYRIMIDINYLAMINO)-
Systematic Name English
CEP 11981 [WHO-DD]
Common Name English
Code System Code Type Description
CAS
856691-93-5
Created by admin on Sat Dec 16 01:57:25 UTC 2023 , Edited by admin on Sat Dec 16 01:57:25 UTC 2023
PRIMARY
ChEMBL
CHEMBL2010872
Created by admin on Sat Dec 16 01:57:25 UTC 2023 , Edited by admin on Sat Dec 16 01:57:25 UTC 2023
PRIMARY
FDA UNII
J8AY0Z4CBP
Created by admin on Sat Dec 16 01:57:25 UTC 2023 , Edited by admin on Sat Dec 16 01:57:25 UTC 2023
PRIMARY
PUBCHEM
11751922
Created by admin on Sat Dec 16 01:57:25 UTC 2023 , Edited by admin on Sat Dec 16 01:57:25 UTC 2023
PRIMARY
EPA CompTox
DTXSID80234942
Created by admin on Sat Dec 16 01:57:25 UTC 2023 , Edited by admin on Sat Dec 16 01:57:25 UTC 2023
PRIMARY
NCI_THESAURUS
C82379
Created by admin on Sat Dec 16 01:57:25 UTC 2023 , Edited by admin on Sat Dec 16 01:57:25 UTC 2023
PRIMARY
Related Record Type Details
ANGIOPOIETIN-1 RECEPTOR
TARGET -> INHIBITOR
IC50
VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2
TARGET -> INHIBITOR
IC50
RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3
TARGET -> INHIBITOR
IC50
TYROSINE-PROTEIN KINASE JAK2
TARGET -> INHIBITOR
IC50
ANAPLASTIC LYMPHOMA KINASE
TARGET -> INHIBITOR
IC50
PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
TARGET -> INHIBITOR
IC50
Structure of CEP-11981 TOSYLATE
SALT/SOLVATE -> PARENT
MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 12
TARGET -> INHIBITOR
IC50
Related Record Type Details
Structure of CEP-11981
ACTIVE MOIETY
NIH
NCATS
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