NOREPINEPHRINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C8H11NO3
Molecular Weight	169.1778
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of NOREPINEPHRINE

Structure Search

SMILES

NC[C@H](O)C1=CC(O)=C(O)C=C1

InChI

InChIKey=SFLSHLFXELFNJZ-QMMMGPOBSA-N

InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C8H11NO3
Molecular Weight	169.1778
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:10:53 UTC 2023` Edited by `admin` on `Fri Dec 15 15:10:53 UTC 2023`
Record UNII	X4W3ENH1CV
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

NOREPINEPHRINE

Official Name

English

NORADRENALINE

Common Name

English

NORADRENALINE [MART.]

Common Name

English

NOREPINEPHRINE [USP IMPURITY]

Common Name

English

NOREPINEPHRINE [MI]

Common Name

English

(-)-NORADRENALINE

Common Name

English

ADRENALINE IMPURITY B [EP IMPURITY]

Common Name

English

NSC-757246

Code

English

LEVARTERENOL

Common Name

English

(-)-.ALPHA.-(AMINOMETHYL)-3,4-DIHYDROXYBENZYL ALCOHOL

Systematic Name

English

(1R)-2-AMINO-1-(3,4-DIHYDROXYPHENYL)ETHANOL

Systematic Name

English

Norepinephrine [WHO-DD]

Common Name

English

NORADRENALINE [JAN]

Common Name

English

norepinephrine [INN]

Common Name

English

1,2-BENZENEDIOL, 4-(2-AMINO-1-HYDROXYETHYL)-, (R)-(R-(R*,R*))-2,3-DIHYDROXYBUTANEDIOATE

Common Name

English

NOR ADRENALIN

Brand Name

English

ADRENALINE TARTRATE IMPURITY B [EP IMPURITY]

Common Name

English

NOREPINEPHRINE [HSDB]

Common Name

English

NOREPINEPHRINE [VANDF]

Common Name

English

Classification Tree Code System Code

LOINC

13782-8

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

LOINC

44837-3

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

LOINC

49552-3

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

LOINC

14852-8

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

WHO-VATC

QC01CA03

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

LOINC

2666-6

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

LOINC

27221-1

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

LOINC

16111-7

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

LOINC

44341-6

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

LOINC

24523-3

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

LOINC

13735-6

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

LOINC

32549-8

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

LOINC

2668-2

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

NDF-RT

N0000007715

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

LOINC

25963-0

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

LOINC

2667-4

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

LOINC

27977-8

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

LOINC

14854-4

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

LOINC

14853-6

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

WHO-ATC

C01CA03

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

NDF-RT

N0000175570

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

Code System Code Type Description

IUPHAR

505

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

PRIMARY

ChEMBL

CHEMBL1437

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

PRIMARY

FDA UNII

X4W3ENH1CV

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

PRIMARY

MESH

D009638

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

PRIMARY

EPA CompTox

DTXSID5023378

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

PRIMARY

DAILYMED

X4W3ENH1CV

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

PRIMARY

CHEBI

33569

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

PRIMARY

CHEBI

18357

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

PRIMARY

SMS_ID

100000083594

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

PRIMARY

EVMPD

SUB09360MIG

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

PRIMARY

HSDB

7772

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

PRIMARY

WIKIPEDIA

Norepinephrine (medication)

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

PRIMARY

NSC

757246

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

PRIMARY

INN

33

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

PRIMARY

DRUG CENTRAL

1960

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

PRIMARY

CAS

51-41-2

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

PRIMARY

ECHA (EC/EINECS)

200-096-6

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

PRIMARY

WIKIPEDIA

NOREPINEPHRINE

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

PRIMARY

DRUG BANK

DB00368

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

PRIMARY

MERCK INDEX

m8054

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

PRIMARY

Merck Index

NCI_THESAURUS

C2321

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

PRIMARY

PUBCHEM

439260

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

PRIMARY

LACTMED

Norepinephrine

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

PRIMARY

RXCUI

7512

Created by admin on Fri Dec 15 15:10:53 UTC 2023 , Edited by admin on Fri Dec 15 15:10:53 UTC 2023

PRIMARY

RxNorm

Related Record Type Details


					ZW81GF408B

NOREPINEPHRINE BITARTRATE ANHYDROUS

SALT/SOLVATE -> PARENT

Amount:


					IFY5PE3ZRW

NOREPINEPHRINE BITARTRATE

SALT/SOLVATE -> PARENT

Amount:


					3T7136LE8K

ALPHA-1A ADRENERGIC RECEPTOR

TARGET -> AGONIST

Amount:


					4A4MK4KIB5

BETA-1 ADRENERGIC RECEPTOR

TARGET -> AGONIST

Interaction Type:

SHORT-ACTING

Amount:


					P5O3A2DHB2

ALPHA-1D ADRENERGIC RECEPTOR

TARGET -> AGONIST

Amount:


					93V99BB37L

ALPHA-2B ADRENERGIC RECEPTOR

TARGET -> AGONIST

Amount:


					50U1BO5G5P

ALPHA-2A ADRENERGIC RECEPTOR

TARGET -> AGONIST

Interaction Type:

SHORT-ACTING


					VZX139UJO5

BETA-2 ADRENERGIC RECEPTOR

TARGET -> AGONIST

Interaction Type:

SHORT-ACTING

Amount:


					17G3192USP

ALPHA-2C ADRENERGIC RECEPTOR

TARGET -> AGONIST

Amount:


					Q7A4S7HOP4

ALPHA-1B ADRENERGIC RECEPTOR

TARGET -> AGONIST

Amount:


					4W6461XR05

NORADRENALINE HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Amount:


					PG244BS39U

BETA-3 ADRENERGIC RECEPTOR

TARGET -> AGONIST

Comments:

Assay in chinese hamster ovary (CHO) cells stably expressing the three β-adrenergic receptor subtypes at comparable leve50 to 80 pM 125I-CYP were used as radioligand. Experiments were done in the presence of 100 µM GTP.

Qualification:

Ki

Amount:


					285VE60914

6-APB

ACTIVATOR OF RELEASE->TARGET

Amount:

Related Record Type Details


					MFB1WL49SZ

(2R)-2-HYDROXY-2-(4-HYDROXY-3-METHOXY-PHENYL)ACETALDEHYDE

METABOLITE -> PARENT

Amount:


					T6M6SQM7LN

DOPGAL

METABOLITE -> PARENT

Amount:


					J7A92W69L7

DROXIDOPA

PRODRUG -> METABOLITE ACTIVE

Amount:


					M8Q69OD5W1

3,4-DIHYDROXYMANDELIC ACID, (R)-

METABOLITE -> PARENT

Amount:


					M19V3799SB

VANILMANDELIC ACID, (-)-

METABOLITE -> PARENT

Amount:

Related Record Type Details


					30Q7KI53AK

EPINEPHRINE BITARTRATE

PARENT -> IMPURITY

Interaction Type:

CHROMATOGRAPHIC PURITY (TLC)

Qualification:

USP

Amount:


					YKH834O4BH

PARENT -> IMPURITY

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					YKH834O4BH

PARENT -> IMPURITY

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					30Q7KI53AK

EPINEPHRINE BITARTRATE

PARENT -> IMPURITY

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:

Related Record Type Details


					X4W3ENH1CV

ACTIVE MOIETY

Amount: